Activating Compound | Comment | Organism | Structure |
---|---|---|---|
hepsin | hepsin activates prostasin by cleaving in the amino-terminal pro-peptide region of prostasin at Arg44 | Homo sapiens | |
matriptase | matriptase activates prostasin by cleaving in the amino-terminal pro-peptide region of prostasin at Arg44 | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expressed in FT-293 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
R44A | the mutant cannot be activated by cleavage through hepsin or matriptase | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | active prostasin does not cleave the epidermal growth factor receptor extracellular domain directly, purified active prostasin also does not cleave purified epidermal growth factor receptor | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PRSS8 | - |
Homo sapiens |