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Synonyms
glutaminase, l-glutaminase, phosphate-activated glutaminase, mitochondrial glutaminase, glutaminase 1, kidney-type glutaminase, phosphate activated glutaminase, glutaminase a, glnase, glutaminase c,
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glutamine aminohydrolase
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glutamine deamidating enzyme
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kidney-type-glutaminase
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L-glutamine amidohydrolase
liver-type glitaminase
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Micrococcus glutaminase Mglu
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Micrococcus luteus K-3-type glutaminase
mitochondrial glutaminase
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neuroblastoma glutaminase
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phosphate activated glutaminase
phosphate-activated glutaminase
phosphate-activated L-glutamine amidohydrolase
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salt-tolerant glutaminase
AnsB
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AoGls
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GA
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GAC
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GAC
splice variant of GLS1
GLS
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GLS1
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GlsA
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glutaminase
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glutaminase
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two isoforms: GAC, KGA
glutaminase A
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glutaminase C
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glutaminase C
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a splicing variant of the kidney-type glutaminase and has the enzyme activity of the phosphate-activated glutaminase
glutaminase K
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glutaminase L
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glutamine amidohydrolase
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glutamine amidohydrolase
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K-glutaminase
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KAG
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KGA
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KGA
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kidney-type glutaminase
kidney-type glutaminase
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kidney-type glutaminase
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kidney-type glutaminase
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kidney-type glutaminase
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L-glutaminase
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L-glutamine amidohydrolase
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L-glutamine amidohydrolase
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L-glutamine amidohydrolase
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L-glutamine amidohydrolase
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L-glutamine amidohydrolase
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L-glutamine amidohydrolase
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L-glutamine amidohydrolase
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L-glutamine amidohydrolase
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LAG
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LGA
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liver-type glutaminase
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liver-type glutaminase
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Micrococcus luteus K-3-type glutaminase
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only from strain RIB40, not from strain MA-27-IM
Micrococcus luteus K-3-type glutaminase
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Micrococcus luteus K-3-type glutaminase
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PAG
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phosphate activated glutaminase
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phosphate activated glutaminase
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phosphate-activated glutaminase
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phosphate-activated glutaminase
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phosphate-activated glutaminase
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phosphate-activated glutaminase
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salt-tolerant glutaminase
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salt-tolerant glutaminase
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salt-tolerant glutaminase
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salt-tolerant glutaminase
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salt-tolerant glutaminase
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2-oxo-glutaramate + H2O
?
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?
2-oxo-succinamate + H2O
?
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?
5-methoxy-2,5-dioxopentanoic acid + H2O
methanol + 2-oxoglutaric acid
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?
6-diazo-5-oxo-L-norleucine + H2O
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the nucleophilic attack of Ser286 sidechain on 6-diazo-5-oxo-L-norleucine releases the diazo group (N2) from the inhibitor and results in the formation of an enzyme-inhibitor complex
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?
alpha-methyl-DL-Gln + H2O
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?
beta-cyanoalanine + H2O
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0.2% of the activity with L-Gln
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?
Cbz-Gln-Gly + H2O
Cbz-Glu-Gly + NH3
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?
Cbz-L-Gln + H2O
Cbz-L-Glu + NH3
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?
D-Asn + H2O
D-aspartate + NH3
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less 0.1% of the activity with L-glutamine and H2O as co-substrate
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?
D-Asn + hydroxylamine
D-2-amino-4-(hydroxylamino)-4-oxobutanoic acid + NH3
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?
D-asparagine + H2O
D-aspartate + NH3
D-gamma-glutamyl-ethylester + H2O
D-Glu + ethanol
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?
D-gamma-glutamyl-ethylester + hydroxylamine
D-gamma-glutamyl hydroxamate + ethanol
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?
D-gamma-glutamyl-hydrazide + H2O
D-Glu + hydroxyhydrazine
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?
D-gamma-glutamyl-hydrazide + hydroxylamine
D-gamma-glutamyl hydroxamate + hydroxyhydrazine
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?
D-gamma-glutamyl-methylester + H2O
D-Glu + methanol
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?
D-gamma-glutamyl-methylester + hydroxylamine
L-gamma-glutamyl hydroxamate + methanol
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?
D-Gln + hydroxylamine
D-gamma-glutamyl hydroxamate + NH3
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glutaminase A and B
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?
D-glutamine + H2O
D-glutamate + NH3
D-theanine + H2O
D-glutamate + ethylamine
gamma-ethyl glutamate + H2O
Glu + ethanol
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?
gamma-ethyl glutamate + hydroxylamine
gamma-glutamyl hydroxamate + ethanol
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?
gamma-glutamyl hydroxamate + NH2OH
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36.3% of the activity with L-glutamine and H2O as co-substrate
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?
gamma-glutamyl-hydrazide + H2O
Glu + hydroxyhydrazine
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?
gamma-glutamyl-hydrazide + hydroxylamine
Glu + hydroxyhydrazine
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?
gamma-glutamyl-hydroxamate + H2O
Glu + hydroxylamine
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?
gamma-glutamyl-hydroxamate + hydroxylamine
gamma-glutamyl hydroxamate + hydroxylamine
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?
gamma-glutamyl-methoxyamide + H2O
Glu + N-hydroxy-O-methylhydroxylamine
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?
gamma-glutamyl-methoxyamide + hydroxylamine
gamma-glutamyl hydroxamate + N-hydroxy-O-methylhydroxylamine
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?
gamma-glutamyl-methylamide + H2O
Glu + N-methylhydroxylamine
gamma-glutamyl-methylamide + hydroxylamine
gamma-glutamyl hydroxamate + N-methylhydroxylamine
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?
gamma-L-glutamyl-4-nitroanilide + H2O
L-glutamate 4-nitroanilide + NH3
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102% activity compared to L-glutamine
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?
gamma-methyl glutamate + H2O
Glu + methanol
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r
gamma-methyl glutamate + hydroxylamine
gamma-glutamyl hydroxamate + methanol
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?
gamma-thioethyl glutamate + H2O
Glu + thioethanol
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?
gamma-thioethyl glutamate + hydroxylamine
gamma-glutamyl hydroxamate + ?
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?
gamma-thiomethyl glutamate + H2O
Glu + thiomethanol
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?
gamma-thiomethyl glutamate + hydroxylamine
gamma-glutamyl hydroxamate + ?
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?
Glu + hydroxylamine
gamma-glutamyl hydroxamate + H2O
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?
glutaramate + H2O
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?
Gly-Asn + H2O
Gly-Asp + NH3
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?
Gly-Gln + H2O
Gly-Glu + NH3
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?
L-Ala-Gln + H2O
L-Ala-L-Glu + NH3
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?
L-albizziin + H2O
? + NH3
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?
L-Asn + H2O
L-aspartate + NH3
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20.6% of the activity with L-glutamine and H2O as co-substrate
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?
L-Asn + hydroxylamine
L-2-amino-4-(hydroxylamino)-4-oxobutanoic acid + NH3
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?
L-asparagine + H2O
L-aspartate + NH3
L-gamma-Gln-methyl ester + H2O
L-Gln + methanol
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?
L-gamma-glutamyl-4-nitroanilide + H2O
L-glutamate 4-nitroanilide + NH3
L-gamma-glutamyl-anilide + H2O
L-Glu + aniline
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?
L-gamma-glutamyl-anilide + hydroxylamine
L-gamma-glutamyl hydroxamate + aniline
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?
L-gamma-glutamyl-ethylester + H2O
L-Glu + ethanol
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?
L-gamma-glutamyl-hydrazide + H2O
L-Glu + hydroxyhydrazine
L-gamma-glutamyl-hydrazide + hydroxylamine
L-gamma-glutamyl hydroxamate + hydroxyhydrazine
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?
L-gamma-glutamyl-L-Ala + H2O
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?
L-gamma-glutamyl-L-Ala + hydroxylamine
gamma-glutamyl hydroxamate + Ala
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?
L-gamma-glutamyl-L-epsilon-Lys + H2O
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L-gamma-glutamyl-L-epsilon-Lys + hydroxylamine
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?
L-gamma-glutamyl-L-Glu + H2O
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?
L-gamma-glutamyl-L-Glu + hydroxylamine
?
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?
L-gamma-glutamyl-methylester + H2O
L-Glu + methanol
L-gamma-glutamyl-methylester + hydroxylamine
L-gamma-glutamyl hydroxamate + methanol
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?
L-gamma-glutamyl-p-nitroanilide + H2O
?
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?
L-gamma-glutamylhydrazine + H2O
?
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?
L-Gln + hydroxylamine
L-gamma-glutamyl hydroxamate + NH3
L-glutamate-p-nitroanilide + H2O
L-glutamate + 4-nitroaniline
L-glutamic acid + NH2OH
gamma-glutamyl hydroxamate
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0.9% of the activity with L-glutamine and H2O as co-substrate
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?
L-glutamine + ethylamine
theanine + NH3
L-glutamine + H2O
L-glutamate + NH3
L-glutamine + H2O
L-glutamic acid + NH3
L-glutamine + NH2OH
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10.3% of the activity with L-glutamine and H2O as co-substrate
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?
L-glutaminyl-L-asparagine + H2O
?
L-isoglutamine + H2O
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?
L-Leu-Ala-Asn + H2O
L-Leu-Ala-Asp + NH3
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?
L-Leu-Gln-Gly + H2O
L-Leu-Glu-Gly + NH3
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?
L-Leu-Gly-Asn + H2O
L-Leu-Gly-Asp + NH3
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?
L-Pro-Leu-Gly-Asn + H2O
L-Pro-Leu-Gly-Asp + NH3
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?
L-Pro-Leu-Gly-Gln + H2O
L-Pro-Leu-Gly-Glu + NH3
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?
L-theanine + H2O
L-glutamate + ethylamine
nitrocefin + H2O
(2R)-2-{(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl}-5-[(E)-2-(2,4-dinitrophenyl)ethenyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
succinamate + H2O
?
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additional information
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D-Asn + H2O
D-Asp + NH3
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26% of the activity with L-Gln
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?
D-Asn + H2O
D-Asp + NH3
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glutaminase A
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?
D-asparagine + H2O
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11% activity compared to L-glutamine
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?
D-asparagine + H2O
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11% activity compared to L-glutamine
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?
D-asparagine + H2O
D-aspartate + NH3
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?
D-asparagine + H2O
D-aspartate + NH3
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?
D-asparagine + H2O
D-aspartate + NH3
44% activity
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?
D-asparagine + H2O
D-aspartate + NH3
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67% of the activity with L-glutamine
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?
D-asparagine + H2O
D-aspartate + NH3
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67% of the activity with L-glutamine
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?
D-Gln + H2O
D-Glu + NH3
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35% of the activity with L-Gln
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?
D-Gln + H2O
D-Glu + NH3
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glutaminase A
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?
D-glutamine + H2O
D-glutamate + NH3
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?
D-glutamine + H2O
D-glutamate + NH3
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?
D-glutamine + H2O
D-glutamate + NH3
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24% activity compared to L-glutamine
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?
D-glutamine + H2O
D-glutamate + NH3
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24% activity compared to L-glutamine
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?
D-glutamine + H2O
D-glutamate + NH3
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48.5% activity compared to L-glutamine
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?
D-glutamine + H2O
D-glutamate + NH3
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48.5% activity compared to L-glutamine
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?
D-glutamine + H2O
D-glutamate + NH3
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low activity
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?
D-glutamine + H2O
D-glutamate + NH3
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low activity
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?
D-glutamine + H2O
D-glutamate + NH3
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?
D-glutamine + H2O
D-glutamate + NH3
65% activity
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?
D-glutamine + H2O
D-glutamate + NH3
92% activity
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?
D-glutamine + H2O
D-glutamate + NH3
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8.1% of the activity with L-glutamine and H2O as co-substrate
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?
D-glutamine + H2O
D-glutamate + NH3
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75% of the activity with L-glutamine
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?
D-glutamine + H2O
D-glutamate + NH3
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75% of the activity with L-glutamine
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?
D-theanine + H2O
D-glutamate + ethylamine
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?
D-theanine + H2O
D-glutamate + ethylamine
57% activity
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?
gamma-glutamyl-methylamide + H2O
Glu + N-methylhydroxylamine
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no activity
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?
gamma-glutamyl-methylamide + H2O
Glu + N-methylhydroxylamine
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?
Gln + H2O
Glu + NH3
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?
Gln + H2O
Glu + NH3
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?
Gln + H2O
Glu + NH3
Clostridium welchii
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r
Gln + H2O
Glu + NH3
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?
Gln + H2O
Glu + NH3
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?
Gln + H2O
Glu + NH3
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?
Gln + H2O
Glu + NH3
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?
Gln + H2O
Glu + NH3
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?
Gln + H2O
Glu + NH3
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?
Gln + H2O
Glu + NH3
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?
Gln + H2O
Glu + NH3
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-
209009, 209010, 209012, 209013, 209015, 209016, 209017, 209018, 209019, 209028, 209029, 209030, 209031, 209033, 209034 -
3.5.1.2 glutaminase
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