Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | phosphate-activated isozyme | Homo sapiens | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
phosphate | phosphate-activated glutaminase isozyme | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamine + H2O | Homo sapiens | intestinal glutaminase activity is increased in liver cirrhosis and correlates with minimal hepatic encephalopathy, relationship between enzyme activity, liver function, and porto-systemic shunts, overview | L-glutamate + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
duodenum | phosphate-activated isozyme, mucosa | Homo sapiens | - |
enterocyte | phosphate-activated isozyme | Homo sapiens | - |
liver | phosphate-activated isozyme, isozyme L-PAG | Homo sapiens | - |
small intestine | phosphate-activated isozyme | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.68 | - |
PAG, healthy liver tissue | Homo sapiens |
2.4 | - |
PAG, cirrhotic disease patient liver tissue | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamine + H2O | - |
Homo sapiens | L-glutamate + NH3 | - |
? | |
L-glutamine + H2O | intestinal glutaminase activity is increased in liver cirrhosis and correlates with minimal hepatic encephalopathy, relationship between enzyme activity, liver function, and porto-systemic shunts, overview | Homo sapiens | L-glutamate + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAG | - |
Homo sapiens |
phosphate-activated glutaminase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Homo sapiens |