Reference on EC 3.4.11.2 - membrane alanyl aminopeptidase and Organism(s) Homo sapiens and UniProt Accession P15144
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Luciani, N.; Marie-Claire, C.; Ruffet, E.; Beaumont, A.; Roques, B.P.; Fournie-Zaluski, M.C.
Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action
Biochemistry
37
686-692
1998
Homo sapiens, Sus scrofa
Menrad, A.; Speicher, D.; Wacker, J.; Herlyn, M.
Biochemical and functional characterization of aminopeptidase N expressed by human melanoma cells
Cancer Res.
53
1450-1455
1993
Homo sapiens
Lalu, K.; Lampelo, S.; Vanha-Perttula, T.
Characterization of three aminopeptidases purified from maternal serum
Biochim. Biophys. Acta
873
190-197
1986
Homo sapiens
Huang, K.; Takahara, S.; Kinouchi, T.; Takeyama, M.; Ishida, T.; Ueyama, H.; Nishi, K.; Ohkubo, I.
Alanyl aminopeptidase from human seminal plasma: purification, characterization, and immunohistochemical localization in the male genital tract
J. Biochem.
122
779-787
1997
Homo sapiens
McClellan, J.B.; Garner, C.W.
Purification and properties of human intestine alanine aminopeptidase
Biochim. Biophys. Acta
613
160-167
1980
Homo sapiens
Olsen, J.; Cowell, G.M.; Konigshofer, E.; Danielsen, E.M.; Moller, J.; Laustsen, L.; Hansen, O.C.; Welinder, K.G.; Engberg, J.; Hunziker, W.; Spiess, M.; Sjstrm, H.; Noren, O.
Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA
FEBS Lett.
238
307-314
1988
Homo sapiens
Tokioka-Terao, M.; Hiwada, K.; Kokubu, T.
Purification and characterization of aminopeptidase N from human plasma
Enzyme
32
65-75
1984
Homo sapiens
Bauvois, B.; Puiffe, M.L.; Bongui, J.B.; Paillat, S.; Monneret, C.; Dauzonne, D.
Synthesis and biological evaluation of novel flavone-8-acetic acid derivatives as reversible inhibitors of aminopeptidase N/CD13
J. Med. Chem.
46
3900-3913
2003
Homo sapiens
Acartuerk, F.; Parlatan, Z.I.; Saracoglu, O.F.
Comparison of vaginal aminopeptidase enzymatic activities in various animals and in humans
J. Pharm. Pharmacol.
53
1499-1504
2001
Cavia porcellus, Oryctolagus cuniculus, Ovis aries, Homo sapiens, Rattus norvegicus
Taracha, E.; Habrat, B.; Lehner, M.; Wislowska, A.; Woronowicz, B.T.; Bogulas, M.; Charewicz, J.; Markuszewski, C.; Plaznik, A.
Alanine aminopeptidase activity in urine: a new marker of chronic alcohol abuse?
Alcohol. Clin. Exp. Res.
28
729-735
2004
Homo sapiens
Lendeckel, U.; Bukowska, A.; Laettig, J.H.; Brandt, W.
Alanyl-aminopeptidases in human T cells. Structures and functions
Aminopeptidases in Biology and Disease (Hooper, N. M. ; Lendechel, U. , eds. )
2
201-227
2004
Homo sapiens
-
Iturrioz, X.; Reaux-Le Goazigo, A.; Llorens-Cortes, C.
Aminopeptidase inhibitors as anti-hypertensive drugs
Aminopeptidases in Biology and Disease (Hooper, N. M. ; Lendechel, U. , eds. )
2
229-250
2004
Homo sapiens
-
Thielitz, A.; Bukowska, A.; Wolke, C.; Vetter, R.; Lendeckel, U.; Wrenger, S.; Hashimoto, Y.; Ansorge, S.; Gollnick, H.; Reinhold, D.
Identification of extra- and intracellular alanyl aminopeptidases as new targets to modulate keratinocyte growth and differentiation
Biochem. Biophys. Res. Commun.
321
795-801
2004
Homo sapiens
Riemann, D.; Tcherkes, A.; Hansen, G.H.; Wulfaenger, J.; Blosz, T.; Danielsen, E.M.
Functional co-localization of monocytic aminopeptidase N/CD13 with the Fc gamma receptors CD32 and CD64
Biochem. Biophys. Res. Commun.
331
1408-1412
2005
Homo sapiens
Saitoh, Y.; Koizumi, K.; Minami, T.; Sekine, K.; Sakurai, H.; Saiki, I.
A derivative of aminopeptidase inhibitor (BE15) has a dual inhibitory effect of invasion and motility on tumor and endothelial cells
Biol. Pharm. Bull.
29
709-712
2006
Homo sapiens
Fontijn, D.; Duyndam, M.C.; van Berkel, M.P.; Yuana, Y.; Shapiro, L.H.; Pinedo, H.M.; Broxterman, H.J.; Boven, E.
CD13/Aminopeptidase N overexpression by basic fibroblast growth factor mediates enhanced invasiveness of 1F6 human melanoma cells
Br. J. Cancer
94
1627-1636
2006
Homo sapiens
Fukasawa, K.; Fujii, H.; Saitoh, Y.; Koizumi, K.; Aozuka, Y.; Sekine, K.; Yamada, M.; Saiki, I.; Nishikawa, K.
Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis
Cancer Lett.
243
135-143
2006
Homo sapiens (P15144), Homo sapiens
Xu, W.; Li, Q.
Progress in the development of aminopeptidase N (APN/CD13) inhibitors
Curr. Med. Chem.
5
281-301
2005
Homo sapiens
Turner, A.J.
Membrane alanyl aminopeptidase
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds. )
1
289-294
2004
Oryctolagus cuniculus, Homo sapiens, Lactococcus lactis, Lymantria dispar, Rattus norvegicus, Sus scrofa
-
Gabrilovac, J.; Cupic, B.; Breljak, D.; Zekusic, M.; Boranic, M.
Expression of CD13/aminopeptidase N and CD10/neutral endopeptidase on cultured human keratinocytes
Immunol. Lett.
91
39-47
2004
Homo sapiens
Chang, Y.W.; Chen, S.C.; Cheng, E.C.; Ko, Y.P.; Lin, Y.C.; Kao, Y.R.; Tsay, Y.G.; Yang, P.C.; Wu, C.W.; Roffler, S.R.
CD13 (aminopeptidase N) can associate with tumor-associated antigen L6 and enhance the motility of human lung cancer cells
Int. J. Cancer
116
243-252
2005
Homo sapiens
Vijgen, L.; Keyaerts, E.; Zlateva, K.; Van Ranst, M.
Identification of six new polymorphisms in the human coronavirus 229E receptor gene (aminopeptidase N/CD13)
Int. J. Infect. Dis.
8
217-222
2004
Homo sapiens (P15144), Homo sapiens
Kehlen, A.; Geisler, M.; Olsen, J.; Sablotzki, A.; Langner, J.; Riemann, D.
IL-10 and TGF-beta differ in their regulation of aminopeptidase N/CD13 expression in monocytes
Int. J. Mol. Med.
13
877-882
2004
Homo sapiens
Alfalah, M.; Krahn, M.P.; Wetzel, G.; von Horsten, S.; Wolke, C.; Hooper, N.; Kalinski, T.; Krueger, S.; Naim, H.Y.; Lendeckel, U.
A mutation in aminopeptidase N (CD13) isolated from a patient suffering from leukemia leads to an arrest in the endoplasmic reticulum
J. Biol. Chem.
281
11894-11900
2006
Homo sapiens
Cowburn, A.S.; Sobolewski, A.; Reed, B.J.; Deighton, J.; Murray, J.; Cadwallader, K.A.; Bradley, J.R.; Chilvers, E.R.
Aminopeptidase N (CD13) regulates tumor necrosis factor-alpha-induced apoptosis in human neutrophils
J. Biol. Chem.
281
12458-12467
2006
Homo sapiens
Roecken, C.; Licht, J.; Roessner, A.; Carl-McGrath, S.
Canalicular immunostaining of aminopeptidase N (CD13) as a diagnostic marker for hepatocellular carcinoma
J. Clin. Pathol.
58
1069-1075
2005
Homo sapiens
Mina-Osorio, P.; Ortega, E.
Aminopeptidase N (CD13) functionally interacts with FcgammaRs in human monocytes
J. Leukocyte Biol.
77
1008-1017
2005
Homo sapiens
Mina-Osorio, P.; Shapiro, L.H.; Ortega, E.
CD13 in cell adhesion: aminopeptidase N (CD13) mediates homotypic aggregation of monocytic cells
J. Leukocyte Biol.
79
719-730
2006
Homo sapiens
Kunii, R.; Nemoto, E.; Kanaya, S.; Tsubahara, T.; Shimauchi, H.
Expression of CD13/aminopeptidase N on human gingival fibroblasts and up-regulation upon stimulation with interleukin-4 and interleukin-13
J. Periodontal Res.
40
138-146
2005
Homo sapiens
Bauvois, B.; Dauzonne, D.
Aminopeptidase-N/CD13 (EC 3.4.11.2) inhibitors: chemistry, biological evaluations, and therapeutic prospects
Med. Res. Rev.
26
88-130
2006
Homo sapiens
Ichimura, E.; Yamada, M.; Nishikawa, K.; Abe, F.; Nakajima, T.
Immunohistochemical expression of aminopeptidase N (CD13) in human lung squamous cell carcinomas, with special reference to bestatin adjuvant therapy
Pathol. Int.
56
296-300
2006
Homo sapiens
Kasman, L.M.
CD13/aminopeptidase N and murine cytomegalovirus infection
Virology
334
1-9
2005
Homo sapiens, Mus musculus
Wentworth, D.E.; Tresnan, D.B.; Turner, B.C.; Lerman, I.R.; Bullis, B.; Hemmila, E.M.; Levis, R.; Shapiro, L.H.; Holmes, K.V.
Cells of human aminopeptidase N (CD13) transgenic mice are infected by human coronavirus-229E in vitro, but not in vivo
Virology
335
185-197
2005
Homo sapiens (P15144), Homo sapiens
Reinhold, D.; Biton, A.; Goihl, A.; Pieper, S.; Lendeckel, U.; Faust, J.; Neubert, K.; Bank, U.; Taeger, M.; Ansorge, S.; Brocke, S.
Dual inhibition of dipeptidyl peptidase IV and aminopeptidase N suppresses inflammatory immune responses
Ann. N. Y. Acad. Sci.
1110
402-409
2007
Homo sapiens, Mus musculus
Thielitz, A.; Reinhold, D.; Vetter, R.; Bank, U.; Helmuth, M.; Hartig, R.; Wrenger, S.; Wiswedel, I.; Lendeckel, U.; Kaehne, T.; Neubert, K.; Faust, J.; Zouboulis, C.C.; Ansorge, S.; Gollnick, H.
Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation
J. Invest. Dermatol.
127
1042-1051
2007
Homo sapiens
Kotlo, K.; Shukla, S.; Tawar, U.; Skidgel, R.A.; Danziger, R.S.
Aminopeptidase N reduces basolateral Na+ -K+ -ATPase in proximal tubule cells
Am. J. Physiol. Renal Physiol.
293
F1047-F1053
2007
Homo sapiens (P15144)
Garde, S.V.; Forte, A.J.; Ge, M.; Lepekhin, E.A.; Panchal, C.J.; Rabbani, S.A.; Wu, J.J.
Binding and internalization of NGR-peptide-targeted liposomal doxorubicin (TVT-DOX) in CD13-expressing cells and its antitumor effects
Anticancer Drugs
18
1189-1200
2007
Homo sapiens
Mina-Osorio, P.; Soto-Cruz, I.; Ortega, E.
A role for galectin-3 in CD13-mediated homotypic aggregation of monocytes
Biochem. Biophys. Res. Commun.
353
605-610
2007
Homo sapiens
Yang, E.; Shim, J.S.; Woo, H.J.; Kim, K.W.; Kwon, H.J.
Aminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3
Biochem. Biophys. Res. Commun.
363
336-341
2007
Homo sapiens, Mus musculus
Petrovic, N.; Schacke, W.; Gahagan, J.R.; OConor, C.A.; Winnicka, B.; Conway, R.E.; Mina-Osorio, P.; Shapiro, L.H.
CD13/APN regulates endothelial invasion and filopodia formation
Blood
110
142-150
2007
Homo sapiens
Terauchi, M.; Kajiyama, H.; Shibata, K.; Ino, K.; Nawa, A.; Mizutani, S.; Kikkawa, F.
Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells
BMC Cancer
7
140
2007
Homo sapiens, Mus musculus
Tsukamoto, H.; Shibata, K.; Kajiyama, H.; Terauchi, M.; Nawa, A.; Kikkawa, F.
Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer
BMC Cancer
8
74
2008
Homo sapiens, Mus musculus
Tokuhara, T.; Hattori, N.; Ishida, H.; Hirai, T.; Higashiyama, M.; Kodama, K.; Miyake, M.
Clinical significance of aminopeptidase N in non-small cell lung cancer
Clin. Cancer Res.
12
3971-3978
2006
Homo sapiens
Demaegdt, H.; Lenaerts, P.J.; Swales, J.; De Backer, J.P.; Laeremans, H.; Le, M.T.; Kersemans, K.; Vogel, L.K.; Michotte, Y.; Vanderheyden, P.; Vauquelin, G.
Angiotensin AT4 receptor ligand interaction with cystinyl aminopeptidase and aminopeptidase N: [125I]angiotensin IV only binds to the cystinyl aminopeptidase apo-enzyme
Eur. J. Pharmacol.
546
19-27
2006
Homo sapiens
Vanderheyden, P.M.; Demaegdt, H.; Swales, J.; Lenaerts, P.J.; De Backer, J.P.; Vogel, L.K.; Vauquelin, G.
Synergistic inhibition of the enzymatic activity of aminopeptidase N by divalent metal ion chelators
Fundam. Clin. Pharmacol.
20
613-619
2006
Homo sapiens, Sus scrofa
Kawamura, J.; Shimada, Y.; Kitaichi, H.; Komoto, I.; Hashimoto, Y.; Kaganoi, J.; Miyake, M.; Yamasaki, S.; Kondo, K.; Imamura, M.
Clinicopathological significance of aminopeptidase N/CD13 expression in human gastric carcinoma
Hepatogastroenterology
54
36-40
2007
Homo sapiens
Yamashita, M.; Kajiyama, H.; Terauchi, M.; Shibata, K.; Ino, K.; Nawa, A.; Mizutani, S.; Kikkawa, F.
Involvement of aminopeptidase N in enhanced chemosensitivity to paclitaxel in ovarian carcinoma in vitro and in vivo
Int. J. Cancer
120
2243-2250
2007
Homo sapiens, Mus musculus
Surowiak, P.; Drag, M.; Materna, V.; Suchocki, S.; Grzywa, R.; Spaczy?ski, M.; Dietel, M.; Oleksyszyn, J.; Zabel, M.; Lage, H.
Expression of aminopeptidase N/CD13 in human ovarian cancers
Int. J. Gynecol. Cancer
16
1783-1788
2006
Homo sapiens
Sonneck, K.; Baumgartner, C.; Rebuzzi, L.; Marth, K.; Chen, K.W.; Hauswirth, A.W.; Florian, S.; Vrtala, S.; Buehring, H.J.; Valenta, R.; Valent, P.
Recombinant allergens promote expression of aminopeptidase-N (CD13) on basophils in allergic patients
Int. J. Immunopathol. Pharmacol.
21
11-21
2008
Homo sapiens
Miki, T.; Takegami, Y.; Okawa, K.; Muraguchi, T.; Noda, M.; Takahashi, C.
The reversion-inducing cysteine-rich protein with Kazal motifs (RECK) interacts with membrane type 1 matrix metalloproteinase and CD13/aminopeptidase N and modulates their endocytic pathways
J. Biol. Chem.
282
12341-12352
2007
Homo sapiens
von Wallbrunn, A.; Waldeck, J.; Hoeltke, C.; Zuehlsdorf, M.; Mesters, R.; Heindel, W.; Schaefers, M.; Bremer, C.
In vivo optical imaging of CD13/APN-expression in tumor xenografts
J. Biomed. Opt.
13
011007
2008
Homo sapiens
Mina-Osorio, P.; Shapiro, L.H.; Ortega, E.
CD13 in cell adhesion: aminopeptidase N (CD13) mediates homotypic aggregation of monocytic cells
J. Leukoc. Biol.
79
719-730
2006
Homo sapiens
Axen, A.; Andersson, H.; Lindeberg, G.; Roennholm, H.; Kortesmaa, J.; Demaegdt, H.; Vauquelin, G.; Karlen, A.; Hallberg, M.
Small potent ligands to the insulin-regulated aminopeptidase (IRAP)/AT(4) receptor
J. Pept. Sci.
13
434-444
2007
Homo sapiens
Gera, L.; Fortin, J.; Adam, A.; Stewart, J.M.; Marceau, F.
Discovery of a dual-function peptide that combines aminopeptidase N inhibition and kinin B1 receptor antagonism
J. Pharmacol. Exp. Ther.
317
300-308
2006
Oryctolagus cuniculus, Homo sapiens
Wulfaenger, J.; Niedling, S.; Riemann, D.; Seliger, B.
Aminopeptidase N (APN)/CD13-dependent CXCR4 downregulation is associated with diminished cell migration, proliferation and invasion
Mol. Membr. Biol.
25
72-82
2008
Homo sapiens
Uehara, N.; Fujita, M.; Shimizu, T.
Colorimetric assay of aminopeptidase N activity based on inhibition of the disassembly of gold nano-composites conjugated with a thermo-responsive copolymer
Anal. Sci.
25
267-273
2009
Homo sapiens
Shim, J.S.; Park, H.M.; Lee, J.; Kwon, H.J.
Global and focused transcriptional profiling of small molecule aminopeptidase N inhibitor reveals its mechanism of angiogenesis inhibition
Biochem. Biophys. Res. Commun.
371
99-103
2008
Homo sapiens
Shang, L.; Fang, H.; Zhu, H.; Wang, X.; Wang, Q.; Mu, J.; Wang, B.; Kishioka, S.; Xu, W.
Design, synthesis and SAR studies of tripeptide analogs with the scaffold 3-phenylpropane-1,2-diamine as aminopeptidase N/CD13 inhibitors
Bioorg. Med. Chem.
17
2775-2784
2009
Homo sapiens
Mawrin, C.; Wolke, C.; Haase, D.; Krueger, S.; Firsching, R.; Keilhoff, G.; Paulus, W.; Gutmann, D.H.; Lal, A.; Lendeckel, U.
Reduced activity of CD13/aminopeptidase N (APN) in aggressive meningiomas is associated with increased levels of SPARC
Brain Pathol.
20
200-210
2009
Homo sapiens
Morikawa, T.; Xie, H.; Wang, T.; Matsuda, H.; Yoshikawa, M.
Acylated flavonol bisdesmosides, sinocrassosides A3-A7 and B3, with aminopeptidase N inhibitory activity from Sinocrassula indica
Chem. Biodivers.
6
411-420
2009
Homo sapiens
Morikawa, T.; Xie, H.; Wang, T.; Matsuda, H.; Yoshikawa, M.
Bioactive constituents from Chinese natural medicines. XXXII. aminopeptidase N and aldose reductase inhibitors from Sinocrassula indica: structures of sinocrassosides B4, B5, C1, and D1-D3
Chem. Pharm. Bull.
56
1438-1444
2008
Homo sapiens
Morikawa, T.; Funakoshi, K.; Ninomiya, K.; Yasuda, D.; Miyagawa, K.; Matsuda, H.; Yoshikawa, M.
Medicinal foodstuffs. XXXIV. Structures of new prenylchalcones and prenylflavanones with TNF-alpha and aminopeptidase N inhibitory activities from Boesenbergia rotunda
Chem. Pharm. Bull.
56
956-962
2008
Homo sapiens
Holdt, B.; Peters, E.; Nagel, H.R.; Steiner, M.
An automated assay of urinary alanine aminopeptidase activity
Clin. Chem. Lab. Med.
46
537-540
2008
Homo sapiens
Ansorge, S.; Bank, U.; Heimburg, A.; Helmuth, M.; Koch, G.; Tadje, J.; Lendeckel, U.; Wolke, C.; Neubert, K.; Faust, J.; Fuchs, P.; Reinhold, D.; Thielitz, A.; Taeger, M.
Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions
Clin. Chem. Lab. Med.
47
253-261
2009
Homo sapiens
Kawai, M.; Araragi, K.; Shimizu, Y.; Hara, Y.
Identification of placental leucine aminopeptidase and triton-slowed aminopeptidase N in serum of pregnant women
Clin. Chim. Acta
400
37-41
2009
Homo sapiens
Stankovic, M.; Vlahovic, P.; Avramovic, V.; Todorovic, M.
Distribution of dipeptidyl peptidase IV in patients with chronic tonsillitis
Clin. Vaccine Immunol.
15
794-798
2008
Homo sapiens
Zhang, X.; Xu, W.
Aminopeptidase N (APN/CD13) as a target for anti-cancer agent design
Curr. Med. Chem.
15
2850-2865
2008
Homo sapiens
Gabrilovac, J.; Breljak, D.; Cupic, B.
Regulation of aminopeptidase N (EC 3.4.11.2; APN; CD13) on the HL-60 cell line by TGF-beta1
Int. Immunopharmacol.
8
613-623
2008
Homo sapiens
Cai, J.; Kehoe, O.; Smith, G.M.; Hykin, P.; Boulton, M.E.
The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.
49
2163-2171
2008
Homo sapiens
Lukaszuk, A.; Demaegdt, H.; Szemenyei, E.; Toth, G.; Tymecka, D.; Misicka, A.; Karoyan, P.; Vanderheyden, P.; Vauquelin, G.; Tourwe, D.
Beta-homo-amino acid scan of angiotensin IV
J. Med. Chem.
51
2291-2296
2008
Homo sapiens
Kuehlmann, U.C.; Chwieralski, C.E.; van den Brule, S.; Roecken, C.; Reinhold, D.; Welte, T.; Buehling, F.
Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases
Life Sci.
84
1-11
2009
Homo sapiens
Li, S.H.; Li, G.; Huang, H.M.; Xiong, F.; Mai, X.; Kuang, B.H.; Liu, C.M.; Tu, G.G.
Synthesis of 1,3,4-thiadiazole derivatives as aminopeptidase N inhibitors
Pharmazie
64
67-70
2009
Homo sapiens
Teranishi, J.; Ishiguro, H.; Hoshino, K.; Noguchi, K.; Kubota, Y.; Uemura, H.
Evaluation of role of angiotensin III and aminopeptidases in prostate cancer cells
Prostate
68
1666-1673
2008
Homo sapiens
Mina-Osorio, P.
The moonlighting enzyme CD13: old and new functions to target
Trends Mol. Med.
14
361-371
2008
Homo sapiens
Grzywa, R.; Oleksyszyn, J.; Salvesen, G.S.; Drag, M.
Identification of very potent inhibitor of human aminopeptidase N (CD13)
Bioorg. Med. Chem. Lett.
20
2497-2499
2010
Homo sapiens, Rattus norvegicus, Sus scrofa
Inagaki, Y.; Tang, W.; Zhang, L.; Du, G.; Xu, W.; Kokudo, N.
Novel aminopeptidase N (APN/CD13) inhibitor 24F can suppress invasion of hepatocellular carcinoma cells as well as angiogenesis
Biosci. Trends
4
56-60
2010
Homo sapiens
Hausheer, F.H.; Parker, A.R.; Petluru, P.N.; Jair, K.W.; Chen, S.; Huang, Q.; Chen, X.; Ayala, P.Y.; Shanmugarajah, D.; Kochat, H.
Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N
Cancer Chemother. Pharmacol.
67
381-391
2011
Homo sapiens
Saxena, A.; Rai, A.; Raina, V.; Seth, T.; Mitra, D.K.
Expression of CD13/aminopeptidase N in precursor B-cell leukemia: role in growth regulation of B cells
Cancer Immunol. Immunother.
59
125-135
2010
Homo sapiens
Cui, S.X.; Qu, X.J.; Gao, Z.H.; Zhang, Y.S.; Zhang, X.F.; Zhao, C.R.; Xu, W.F.; Li, Q.B.; Han, J.X.
Targeting aminopeptidase N (APN/CD13) with cyclic-imide peptidomimetics derivative CIP-13F inhibits the growth of human ovarian carcinoma cells
Cancer Lett.
292
153-162
2010
Homo sapiens
Gong, Q.; Shi, W.; Li, L.; Ma, H.
Leucine aminopeptidase may contribute to the intrinsic resistance of cancer cells toward cisplatin as revealed by an ultrasensitive fluorescent probe
Chem. Sci.
7
788-792
2016
Homo sapiens (P28838)
Bizon, A.; Milnerowicz, H.
The effect of passive and active exposure to tobacco smoke on lipid profile parameters and the activity of certain membrane enzymes in the blood of women in the first trimester of pregnancy
Environ. Toxicol. Pharmacol.
53
74-80
2017
Homo sapiens (P15144), Homo sapiens
Weglarz-Tomczak, E.; Berlicki, L.; Pawelczak, M.; Nocek, B.; Joachimiak, A.; Mucha, A.
A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases
Eur. J. Med. Chem.
117
187-196
2016
Homo sapiens (P15144), Neisseria meningitidis serogroup B (Q9JYV4), Neisseria meningitidis serogroup B MC58 (Q9JYV4)
