Activating Compound | Comment | Organism | Structure |
---|---|---|---|
transforming growth factor-beta1 | transforming growth factor-beta1 at physiological concentrations (0.16 to 2.5 ng/ml) increases expression of CD13 both at mRNA and membrane protein level in a time- and concentration-dependent manner, increased membrane CD13 expression is associated with an increase of its enzyme activity, actinomycin-D abrogates the transforming growth factor-beta1-induced up-regulation of CD13 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | dependent on | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HL-60 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Ala-p-nitroanilide + H2O | - |
Homo sapiens | L-Ala + p-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aminopeptidase N | - |
Homo sapiens |
APN | - |
Homo sapiens |
CD13 | - |
Homo sapiens |