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Literature summary for 3.4.11.2 extracted from

  • Mina-Osorio, P.; Ortega, E.
    Aminopeptidase N (CD13) functionally interacts with FcgammaRs in human monocytes (2005), J. Leukocyte Biol., 77, 1008-1017.
    View publication on PubMed
Search for more literature for 3.4.11.2

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
-
 Homo sapiens 9986
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plasma membrane bound Homo sapiens 5886
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Metals/Ions

Metals/Ions Comment Organism Structure
additional information metallopeptidase Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme acts as a cellsuface receptor for cells leading to rapid FcgammaRI-mediated phagocytosis of the cells, functionally interacts and partially co-localizes with FcgammaRs in monocytes, cross-linking of cells via the cytoplasmic portion of the enzyme triggers intracellular signalling, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
monocyte of peripheral blood Homo sapiens
-
U-937 cell promonocytic cell line Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme acts as a cellsuface receptor for cells leading to rapid FcgammaRI-mediated phagocytosis of the cells, functionally interacts and partially co-localizes with FcgammaRs in monocytes, cross-linking of cells via the cytoplasmic portion of the enzyme triggers intracellular signalling, overview Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
aminopeptidase N
-
 Homo sapiens
CD13
-
 Homo sapiens