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Literature summary for 3.4.11.2 extracted from

  • Ichimura, E.; Yamada, M.; Nishikawa, K.; Abe, F.; Nakajima, T.
    Immunohistochemical expression of aminopeptidase N (CD13) in human lung squamous cell carcinomas, with special reference to bestatin adjuvant therapy (2006), Pathol. Int., 56, 296-300.
    View publication on PubMed
Search for more literature for 3.4.11.2

Inhibitors

Inhibitors Comment Organism Structure
bestatin acts as an anti-tumor agent in lung squamous cell carcinoma cells and prolonged survival time of patients with completely resected stage I lung squamous cell carcinoma Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is involved in angiogenesis and cell proliferation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood vessel surrounding a lung tumor nest Homo sapiens
-
fibroblast surrounding a lung tumor nest Homo sapiens
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lung normal and neoplastic tissue, CD13 expression analysis, low expression of CD13 in adenocarcinoma and adenosquamous cell carcinoma, overview Homo sapiens
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lung squamous cell carcinoma cell CD13 expression analysis, interstitial tissue, blood vessels, and fibroblasts surrounding the tumor nest Homo sapiens
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additional information the CD13 expression level seems to be correlated with tumor angiogenesis resulting in tumor invasion Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in angiogenesis and cell proliferation Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
aminopeptidase N
-
 Homo sapiens
CD13
-
 Homo sapiens