Information on EC 3.1.3.25 - inositol-phosphate phosphatase

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The expected taxonomic range for this enzyme is: Eukaryota, Archaea, Bacteria

EC NUMBER
COMMENTARY
3.1.3.25
-
RECOMMENDED NAME
GeneOntology No.
inositol-phosphate phosphatase
PATHWAY
KEGG Link
MetaCyc Link
Biosynthesis of secondary metabolites
-
D-myo-inositol (1,4,5)-trisphosphate degradation
-
Inositol phosphate metabolism
-
Metabolic pathways
-
myo-inositol biosynthesis
-
phytate degradation I
-
Streptomycin biosynthesis
-
SYSTEMATIC NAME
IUBMB Comments
myo-inositol-phosphate phosphohydrolase
Acts on five of the six isomers of myo-inositol phosphate, all except myo-inositol 2-phosphate, but does not act on myo-inositol bearing more than one phosphate group. It also acts on adenosine 2'-phosphate (but not the 3'- or 5'- phosphates), sn-glycerol 3-phosphate and glycerol 2-phosphate. Two isoforms are known [4].
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
AF2372
O30298
exhibits NADP(H) phosphatase and fructose-1,6-bisphosphatase activities in addition to inositol monophosphatase activitity, but not 3'-phosphoadenosine 5'-phosphate phosphatase activity
AF2372
O30298
gene name
I-1-Pase
-
-
-
-
IMP
-
-
-
-
IMP
Q6NPM8, Q94F00, Q9M8S8
-
IMP-1 protein
B3DFH0
-
IMPA1
P29218
-
IMPA2
O14732
-
IMPase
-
-
-
-
IMPase
-
-
IMPase
-
-
IMPase
B3DFH0
-
IMPase
O14732, P29218
-
IMPase
Mycobacterium tuberculosis H37Rv, ATCC 25618
-
-
-
IMPase
Q6G709
-
IMPase
Staphylococcus aureus MSSA476
Q6G709
-
-
IMPase
O33832
-
IMPase/FBPase
-
-
IMPase/FBPase
O30298
-
IMPP
-
-
inositol 1-phosphate phosphatase
-
-
-
-
inositol 1-phosphate phosphatase
O33832
-
inositol monophosphatase
-
-
-
-
inositol monophosphatase
-
-
inositol monophosphatase
Q6NPM8, Q94F00, Q9M8S8
-
inositol monophosphatase
O30298
-
inositol monophosphatase
-
-
inositol monophosphatase
-
-
inositol monophosphatase
-
-
inositol monophosphatase
-
-
inositol monophosphatase
Q6G709
-
inositol monophosphatase
Staphylococcus aureus MSSA476
Q6G709
-
-
inositol monophosphatase
-
-
inositol monophosphatase/fructose-1,6-bisphosphatase
-
-
inositol monophosphate phosphatase
-
-
-
-
inositol monophosphate phosphatase
-
-
inositol monophosphate phosphatase
Mycobacterium tuberculosis H37Rv, ATCC 25618
-
-
-
inositol phosphatase
-
-
-
-
inositol phosphatase
O30298
-
inositol phosphatase
-
-
inositol phosphatase
-
-
inositol phosphatase
-
-
inositol phosphohydrolase
-
-
-
-
inositol-1(or 4)-monophosphatase
-
-
-
-
inositol-1(or 4)-monophosphatase
-
-
inositol-1-phosphatase
-
-
-
-
L-myo-inositol 1-phosphate phosphatase
-
-
L-myo-inositol-1-phosphate phosphatase
-
-
-
-
Lithium-sensitive myo-inositol monophosphatase A1
-
-
-
-
myo-inositol 1 (or 4) -monophosphatase
-
-
-
-
myo-inositol 1 (or 4) monophosphatase
-
-
myo-inositol 1-phosphatase
-
-
-
-
myo-inositol monophosphatase
Q6NPM8, Q94F00, Q9M8S8
-
myo-inositol monophosphatase
-
-
myo-inositol monophosphatase
-
-
myo-inositol monophosphatase
O14732, P29218
-
myo-inositol monophosphatase 1
-
-
myo-inositol monophosphatase 2
-
-
Myo-inositol monophosphatase A2
-
-
-
-
myo-inositol monophosphatase-1
P97697
-
myo-inositol monophosphate phosphatase
-
-
myo-inositol-1(or 4)-phosphate phosphohydrolase
-
-
-
-
myo-inositol-1-phosphatase
-
-
myo-inositol-1-phosphatase/aryl-phosphatase
-
exhibits also Zn-dependent aryl-phosphatase activity at acidic pH
myo-inositol-1-phosphate phosphohydrolase
-
-
myo-inositol-phosphatase
-
-
SAS2203
Q6G709
gene name
SAS2203
Staphylococcus aureus MSSA476
Q6G709
gene name
-
SuhB
O30298
gene name
TM1415
O33832
exhibits dual specificity with both IMPase and fructose-1,6-bisphosphatase activities
MJ0109
-
exhibits NADP(H) phosphatase and fructose-1,6-bisphosphatase activities in addition to the inositol monophosphatase activity, but not 3'-phosphoadenosine 5'-phosphate phosphatase activity
additional information
-
archeal enzyme displays inositol monophosphatase as well as fructose 1,6-bisphosphatase activity
additional information
Methanocaldococcus jannaschii MJ0109
-
archeal enzyme displays inositol monophosphatase as well as fructose 1,6-bisphosphatase activity
-
additional information
Q6G709
the enzyme belongs to the FIG superfamily of proteins
additional information
Staphylococcus aureus MSSA476
Q6G709
the enzyme belongs to the FIG superfamily of proteins
-
CAS REGISTRY NUMBER
COMMENTARY
37184-63-7
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
gene Impa1
-
-
Manually annotated by BRENDA team
IMPL1; ecotype Columbia-0, genes IMPL1, IMPL2, and VTC4
UniProt
Manually annotated by BRENDA team
IMPL2; ecotype Columbia-0, genes IMPL1, IMPL2, and VTC4
UniProt
Manually annotated by BRENDA team
syncytia induced by nematode Heterodera schachtii
UniProt
Manually annotated by BRENDA team
VTC4; ecotype Columbia-0, genes IMPL1, IMPL2, and VTC4
UniProt
Manually annotated by BRENDA team
Archaeoglobus fulgidus AF2372
strain AF2372
-
-
Manually annotated by BRENDA team
gene suhB
-
-
Manually annotated by BRENDA team
gene IMPA2
-
-
Manually annotated by BRENDA team
cv. Harrington, wild-type and mutant
SwissProt
Manually annotated by BRENDA team
Methanocaldococcus jannaschii MJ0109
strain MJ0109
-
-
Manually annotated by BRENDA team
IMPA1
P29218
SwissProt
Manually annotated by BRENDA team
IMPA2
SwissProt
Manually annotated by BRENDA team
strain MC2 155
-
-
Manually annotated by BRENDA team
Mycobacterium smegmatis MC2 155
strain MC2 155
-
-
Manually annotated by BRENDA team
genes impA or Rv1604, and impC or Rv3137
-
-
Manually annotated by BRENDA team
strain H37Rv, gene Rv2131c
-
-
Manually annotated by BRENDA team
Mycobacterium tuberculosis H37Rv, ATCC 25618
genes impA or Rv1604, and impC or Rv3137
-
-
Manually annotated by BRENDA team
bv. trifolii
-
-
Manually annotated by BRENDA team
stains RS16, RS347, RS1238 and YML89
-
-
Manually annotated by BRENDA team
gene sas2203
UniProt
Manually annotated by BRENDA team
Staphylococcus aureus MSSA476
gene sas2203
UniProt
Manually annotated by BRENDA team
strain PCC 6803
-
-
Manually annotated by BRENDA team
strain TM1415
-
-
Manually annotated by BRENDA team
Thermotoga maritima TM1415
strain TM1415
-
-
Manually annotated by BRENDA team
Methanocaldococcus jannaschii MJ109
strain MJ109
Uniprot
Manually annotated by BRENDA team
additional information
-
-
-
Manually annotated by BRENDA team
pI VALUE
pI VALUE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
5.9
-
-
isoelectric focusing
PDB
SCOP
CATH
ORGANISM
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Staphylococcus aureus (strain MSSA476)
Staphylococcus aureus (strain MSSA476)
Staphylococcus aureus (strain MSSA476)
Staphylococcus aureus (strain MSSA476)
Staphylococcus aureus (strain MSSA476)
Staphylococcus aureus (strain MSSA476)
Staphylococcus aureus (strain MSSA476)
Staphylococcus aureus (strain MSSA476)
Staphylococcus aureus (strain MSSA476)
EXPRESSION
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
increase in mRNA expression in kidney and gill after 2 days after transfer from freshwater to seawater, no expression detected in the intestine
-
up to 17fold increases in mRNA expression and 2fold increases in protein abundance in major osmoregulatory tissues following transfer of fish to seawater
-