Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Li+ | lithium impairs neuronal phosphatidylinositol 4,5-bisphosphate synthesis through inhibition of the enzyme | Caenorhabditis elegans |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
myo-inositol phosphate + H2O | Caenorhabditis elegans | - |
myo-inositol + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
myo-inositol phosphate + H2O | - |
Caenorhabditis elegans | myo-inositol + phosphate | - |
? | |
phosphatidylinositol 4,5-bisphosphate + H2O | - |
Caenorhabditis elegans | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IMPase | - |
Caenorhabditis elegans |
myo-inositol monophosphatase | - |
Caenorhabditis elegans |
General Information | Comment | Organism |
---|---|---|
malfunction | mutations that degrade membrane phosphatidylinositol 4,5-bisphosphate suppress the synaptic defects of the enzyme mutants and confer resistance to lithium treatment | Caenorhabditis elegans |
physiological function | the enzyme is essential for polarized localization of synaptic molecules | Caenorhabditis elegans |