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4.1.1.9: malonyl-CoA decarboxylase

This is an abbreviated version!
For detailed information about malonyl-CoA decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.9

Reaction

malonyl-CoA
=
acetyl-CoA
 +
CO2

Synonyms

Acyl-CoA: malonate CoA transferase/malonyl-CoA decarboxylase, Decarboxylase, malonyl coenzyme A, hMCD, malonyl CoA decarboxylase, Malonyl coenzyme A decarboxylase, Malonyl-CoA decarboxylase, malonyl-CoA decarboxylase/acetyltransferase, malonyl-coenzyme A decarboxylase, MCD, MLYCD

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.9 malonyl-CoA decarboxylase

Inhibitors

Inhibitors on EC 4.1.1.9 - malonyl-CoA decarboxylase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
((3-phenylpropionyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)acetic acid
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-
((3-phenylpropionyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)acetic acid methyl ester
-
-
((morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)acetic acid methyl ester
-
-
(2E)-3-(5-methyl-4-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)isoxazol-3-yl)prop-2-enenitrile
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-
(2E)-3-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)prop-2-enenitrile
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-
(2E)-3-[2-(1-methylethyl)-1-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)-4,5-dihydro-1H-imidazol-5-yl]prop-2-enenitrile
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-
(2E)-3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]prop-2-enenitrile
-
-
(2E)-3-[2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]prop-2-enoic acid
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(2Z)-3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]prop-2-enenitrile
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-
(4E)-2-(1-methylethyl)-3-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)-3,5-dihydro-4H-imidazol-4-one O-ethyloxime
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-
(4E)-2-(1-methylethyl)-3-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)-3,5-dihydro-4H-imidazol-4-one oxime
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(4E)-2-(1-methylethyl)-3-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-3,5-dihydro-4H-imidazol-4-one O-(2-methylpropyl)oxime
(4E)-2-(1-methylethyl)-3-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-3,5-dihydro-4H-imidazol-4-one O-ethyloxime
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(4E)-2-(1-methylethyl)-3-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-3,5-dihydro-4H-imidazol-4-one O-methyloxime
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(4E)-2-(1-methylethyl)-3-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-3,5-dihydro-4H-imidazol-4-one O-phenyloxime
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(4E)-2-(1-methylethyl)-3-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-3,5-dihydro-4H-imidazol-4-one O-tert-butyloxime
(4E)-2-(1-methylethyl)-3-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-3,5-dihydro-4H-imidazol-4-one oxime
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(isobutyryl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)acetic acid
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(isobutyryl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)acetic acid methyl ester
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1,1,1,3,3,3-hexafluoro-2-(2-phenoxy-1,3-thiazol-5-yl)propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-(2-[4-[3-(2H-tetrazol-2-yl)phenyl]piperazin-1-yl]-1,3-thiazol-5-yl)propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-(2-[4-[3-(methylsulfonyl)phenyl]piperazin-1-yl]-1,3-thiazol-5-yl)propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-(2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-5-yl)propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-(2-[4-[4-(methylsulfonyl)phenyl]piperazin-1-yl]-1,3-thiazol-5-yl)propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-(2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]-1,3-thiazol-5-yl)propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-(2-[[4-(trifluoromethyl)phenyl]sulfonyl]-1,3-thiazol-5-yl)propan-2-ol
-
-
1,1,1,3,3,3-hexafluoro-2-(4-[(5E)-2-(1-methylethyl)-5-[(phenylperoxy)imino]-4,5-dihydro-1H-imidazol-1-yl]phenyl)propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-(4-[5-(1-hydroxyethyl)-2-(1-methylpropyl)-1H-imidazol-1-yl]phenyl)propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-(4-[5-(hydroxymethyl)-2-(1-methylethyl)-1H-imidazol-1-yl]phenyl)propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-(4-[5-(hydroxymethyl)-2-pyridin-4-yl-1H-imidazol-1-yl]phenyl)propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-(4-[5-[hydroxy(phenoxy)methyl]-2-(1-methylpropyl)-1H-imidazol-1-yl]phenyl)propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-(4-[5-[hydroxy(phenyl)methyl]-2-(1-methylpropyl)-1H-imidazol-1-yl]phenyl)propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-(1-phenylpiperidin-4-yl)-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-(4-phenylpiperazin-1-yl)-1,3-thiazol-5-yl]propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-[2-(4-phenylpiperidin-1-yl)-1,3-thiazol-5-yl]propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-[2-[(4-methylphenyl)sulfanyl]-1,3-thiazol-5-yl]propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-[2-[1-(3-fluorophenyl)piperidin-4-yl]-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-[1-(4-fluorophenyl)piperidin-4-yl]-1,3-thiazol-5-yl]propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-[2-[4-(2-fluorophenyl)-4-(2H-tetrazol-2-yl)piperidin-1-yl]-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-[4-(3-fluorophenyl)piperazin-1-yl]-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-[4-(3-fluorophenyl)piperidin-1-yl]-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-[4-(3-methoxyphenyl)piperazin-1-yl]-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-[4-(3-nitrophenyl)piperazin-1-yl]-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-[4-(4-fluorophenyl)piperazin-1-yl]-1,3-thiazol-5-yl]propan-2-ol
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-
1,1,1,3,3,3-hexafluoro-2-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-[4-(4-methylphenyl)piperazin-1-yl]-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[2-[4-(4-nitrophenyl)piperazin-1-yl]-1,3-thiazol-5-yl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[(4-methylphenyl)sulfanyl]phenyl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[2-(1-methylethyl)-4-(trifluoromethyl)-1H-imidazol-1-yl]phenyl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[2-(1-methylethyl)-5-([[5-(1H-tetrazol-5-yl)pentyl]oxy]methyl)-1H-imidazol-1-yl]phenyl]propan-2-ol
1,1,1,3,3,3-hexafluoro-2-[4-[2-(1-methylethyl)-5-[[4-(1H-tetrazol-5-yl)butoxy]methyl]-1H-imidazol-1-yl]phenyl]propan-2-ol
1,1,1,3,3,3-hexafluoro-2-[4-[4-(hydroxymethyl)-2-(1-methylethyl)-1H-imidazol-1-yl]phenyl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[5-(1-hydroxyethyl)-2-(1-methylpropyl)-1H-imidazol-1-yl]phenyl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[5-(hydroxymethyl)-2-(1-methylethyl)-1H-imidazol-1-yl]phenyl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[5-(hydroxymethyl)-2-(1-methylpropyl)-1H-imidazol-1-yl]phenyl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[5-(hydroxymethyl)-2-pyridin-2-yl-1H-imidazol-1-yl]phenyl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[5-(hydroxymethyl)-2-pyridin-4-yl-1H-imidazol-1-yl]phenyl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[5-[[(1-methylethyl)amino]methyl]-2-(1-methylpropyl)-1H-imidazol-1-yl]phenyl]propan-2-ol
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1,1,1,3,3,3-hexafluoro-2-[4-[5-[[(2-methoxyethyl)amino]methyl]-2-(1-methylpropyl)-1H-imidazol-1-yl]phenyl]propan-2-ol
1,3-bis(2-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]urea
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1,3-diethyl-1-(8-hydroxyoctyl)-3-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]urea
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1,3-diethyl-1-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-(4-hydroxybutyl)urea
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1,3-diethyl-3-(4-hydroxybutyl)-1-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]urea
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1,3-dimethyl-1-(2-methylpropyl)butyl 3-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]butanoate
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1,3-dimethyl-1-(2-methylpropyl)butyl N-([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)-beta-alaninate
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1-(2-cyanoethyl)-3-ethyl-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]urea
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1-(2-phenylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]urea
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1-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)-3-(2-phenylethyl)urea
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1-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)-3-phenylurea
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1-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)butan-1-one
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1-benzyl-3-methyl-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]urea
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1-carbamoyl-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]piperidinium
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1-carbamoyl-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]pyrrolidinium
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1-cyclohexyl-3-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)urea
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1-ethyl-1-methylpropyl (3S)-3-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]butanoate
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1-ethyl-1-methylpropyl N-([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)-beta-alaninate
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1-ethyl-1-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3,3-dimethylurea
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1-ethyl-3,3-dimethyl-1-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]urea
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1-ethyl-3,3-dimethyl-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]urea
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1-ethyl-3-(4-hydroxybutyl)-1-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)urea
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1-ethyl-3-methyl-1-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)urea
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1-methoxy-3-methyl-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]urea
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1-methyl-3-phenyl-1-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]urea
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1-methyl-3-phenyl-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]urea
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-
1-phenyl-3-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]urea
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1-[2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]butan-1-ol
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1-[3-(4-hydroxyphenyl)-5-(thiophen-3-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
-
1-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-1-methyl-3-phenylurea
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1-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-phenylurea
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-
1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]-4-phenyl-N-(2,2,2-trifluoroethyl)piperidine-4-carboxamide
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1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]-4-phenylpiperidin-4-ol
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1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]-4-phenylpiperidine-4-carbonitrile
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1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]-4-phenylpiperidine-4-carboxamide
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1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]-4-phenylpiperidine-4-carboxylic acid
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1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]-N-(methylsulfonyl)-4-phenylpiperidine-4-carboxamide
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1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]-N-methyl-4-phenylpiperidine-4-carboxamide
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1-[5-(2,4-dibromophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
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1-[5-(2,4-dichlorophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
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1-[5-(2,4-difluorophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
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1-[5-(2,4-dimethoxyphenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-l]ethanone
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1-[5-(3,4-dibromophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
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1-[5-(3,4-dichlorophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
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1-[5-(4-chlorophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
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1-[5-(4-hydroxyphenyl)-3-(thiophen-3-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
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1-[5-(furan-3-yl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
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2,2'-dipyridyl
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2,2,2-trifluoro-1-[4-(pyrrolidin-1-ylcarbonyl)phenyl]ethanone
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2-(4-[1-[3,4-bis(difluoromethoxy)phenyl]-2-(1-oxidopyridin-4-yl)ethyl]-3-methylphenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
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2-(4-[5-amino-3-(1-methylethyl)isoxazol-4-yl]phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
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2-(4-[5-amino-3-[(2E)-but-2-en-1-yl]isoxazol-4-yl]phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
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2-(4-[5-[(butylamino)methyl]-2-(1-methylethyl)-1H-imidazol-1-yl]phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
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2-(4-[5-[(butylamino)methyl]-2-(1-methylpropyl)-1H-imidazol-1-yl]phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol
2-ethyl-N-[3-(1-methylethyl)-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-5-yl]hexanamide
2-methyl-1-[2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]propan-1-ol
2-methyl-3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]propanoic acid
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2-methyl-3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4,5-dihydro-1H-imidazol-5-yl]propanoic acid
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2-methyl-N-(3-phenyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-5-yl)propanamide
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2-methyl-N-(3-pyridin-4-yl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-5-yl)propanamide
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2-methyl-N-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)propanamide
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2-methyl-N-(pyridin-4-ylmethyl)-N-[5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-1,3-thiazol-2-yl]propanamide
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2-methyl-N-propyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
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2-methyl-N-[4-(1H-tetrazol-5-yl)butyl]-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
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2-methyl-N-[4-(trifluoroacetyl)phenyl]propanamide
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2-phenoxy-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]acetamide
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2-phenoxy-N-[4-(trifluoroacetyl)phenyl]acetamide
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2-phenoxy-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]acetamide
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2-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]ethyl (1Z)-2-methyl-N-(1-methylethyl)propanimidoate
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2-[1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]benzoic acid
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-
2-[2-(1-methylpropyl)-5-propyl-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4,5-dihydro-1H-imidazol-5-yl]ethenone
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2-[2-[4-(3,4-difluorophenyl)piperazin-1-yl]-1,3-thiazol-5-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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2-[2-[4-(3-aminophenyl)piperazin-1-yl]-1,3-thiazol-5-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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2-[2-[4-(3-chlorophenyl)piperazin-1-yl]-1,3-thiazol-5-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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-
2-[2-[4-(4-aminophenyl)piperazin-1-yl]-1,3-thiazol-5-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
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2-[3-(4-hydroxyphenyl)-5-(4-methoxy-2-nitrophenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[3-(4-hydroxyphenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[3-(4-hydroxyphenyl)-5-(thiophen-3-yl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[3-(4-hydroxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[4-(3,5-dimethylisoxazol-4-yl)phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
2-[4-(5-amino-3-benzylisoxazol-4-yl)phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[4-(5-amino-3-butylisoxazol-4-yl)phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[4-(5-amino-3-ethylisoxazol-4-yl)phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[4-(5-amino-3-furan-3-ylisoxazol-4-yl)phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[4-(5-amino-3-phenylisoxazol-4-yl)phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[4-(5-amino-3-pyridin-4-ylisoxazol-4-yl)phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]benzoic acid
-
-
2-[4-[5-amino-3-(1-methylethyl)isoxazol-4-yl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[4-[5-amino-3-(4-methoxyphenyl)isoxazol-4-yl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[4-[5-amino-3-(ethoxymethyl)isoxazol-4-yl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[4-[5-amino-3-(trifluoromethyl)isoxazol-4-yl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol
-
-
2-[5-(2,4-dibromophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[5-(2,4-dinitrophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[5-(3,4-difluorophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[5-(3,5-dimethoxyphenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[5-(4-bromophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[5-(4-nitrophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[5-(furan-3-yl)-3-(4-hydroxy-3,5-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[5-(furan-3-yl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
2-[5-(pyridin-2-yl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazol-4(5H)-one
-
3-((morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)propionic acid
3-((morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)propionic acid methyl ester
3-(1-methylethyl)-1-[[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]methyl]-1-(2-morpholin-4-ylethyl)urea
-
-
3-(1-methylethyl)-N-pyridin-4-yl-4(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)isoxazole-5-carboxamide
-
-
3-(1-methylethyl)-N-[(2E)-3-phenylprop-2-en-1-yl]-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazole-5-carboxamide
-
-
3-(2-methylpropyl)-1-propyl-1-[4-(trifluoroacetyl)phenyl]urea
-
-
3-(5-amino-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)propan-1-ol
-
-
3-(5-amino-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)propanoic acid
-
-
3-Bromopyruvate
3-methyl-1-(2-phenylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]urea
-
-
3-nitrophenyl 3-[(2-methylpropyl)(phenylcarbonyl)amino]propaneperoxoyl-4-(trifluoroacetyl)benzamide
-
-
3-phenyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]propionamide
-
-
3-phenyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
3-[(morpholin-4-ylcarbonyl)[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]propanoic acid
-
-
3-[1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]-N-methylbenzamide
-
-
3-[1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]benzamide
-
-
3-[1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]benzoic acid
-
-
3-[2-(1-methylethyl)-1-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)-4,5-dihydro-1H-imidazol-5-yl]propanoic acid
-
-
3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]propanoic acid
-
-
3-[2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]propanoic acid
-
-
3-[2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4,5-dihydro-1H-imidazol-5-yl]propanoic acid
-
-
3-[4-carbamoyl-1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]benzoic acid
-
-
3-[4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]-N-methylbenzamide
-
-
3-[4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]benzamide
-
-
3-[4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]benzoic acid
-
-
3-[4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]benzonitrile
-
-
3-[4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]benzamide
-
-
3-[[(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)carbamoyl]amino]propanoic acid
-
-
4-((morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)butyric acid methyl ester
4-(2-amino-1,3-thiazol-4-yl)-7-[[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]sulfanyl]-2H-chromen-2-ol
-
-
4-(3-carboxyphenyl)-1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidine-4-carboxylic acid
-
-
4-(4-fluorophenyl)-1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidine-4-carboxylic acid
-
-
4-(5-amino-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)phenol
-
-
4-(trifluoroacetyl)-N-[3-(trifluoromethyl)phenyl]benzamide
-
-
4-carbamoyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholin-4-ium
-
-
4-cyano-N-ethyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzamide
-
-
4-cyano-N-ethyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]benzamide
4-cyano-N-ethyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide
-
-
4-cyano-N-[3-(1-methylethyl)-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-5-yl]benzamide
-
-
4-cyano-N-[4-(trifluoroacetyl)phenyl]benzamide
-
-
4-cyclohexyl-1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidine-4-carboxylic acid
-
-
4-cyclopropyl-1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidine-4-carboxylic acid
-
-
4-[1-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperidin-4-yl]benzoic acid
-
-
4-[4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]benzoic acid
-
-
4-[4-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]benzonitrile
-
-
5-((morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)pentanoic acid
-
-
5-((morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)pentanoic acid methyl ester
5-(isobutyryl-[4-(2,2,2-trifluoro-1-hydroxy-1 trifluoromethylethyl)phenyl]amino)pentanoic acid methyl ester
-
-
5-(isobutyryl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)pentanoic acid
5-(isobutyryl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amino)pentanoic acid methyl ester
5-methyl-N-pyridin-4-yl-4-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)isoxazole-3-carboxamide
-
-
5-[(2-methylpropanoyl)[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]pentanoic acid
-
-
5-[(morpholin-4-ylcarbonyl)[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]pentanoic acid
-
-
5-[(morpholine-4-carbonyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]-amino]-pentanoic acid methyl ester
-
30% inhibition at 0.08 mg/ml, 50% inhibition at approximately 0.16 mg/ml
5-[[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]methoxy]pentanenitrile
5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl](2-methylpropanoyl)amino]pentanoic acid
-
-
5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl](morpholin-4-ylcarbonyl)amino]pentanoic acid
-
-
6-[[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]methoxy]hexanenitrile
Acetic anhydride
-
0.01 mg MCD is incubated with the 3fold excess of acetic anhydride leading to 70% loss of activity after 30 min
acetyl-CoA
ADP
-
inhibition at 2 mM
Avidin
-
CBM-3001106
-
CBM-301940
-
0.01 mM, 85% inhibition
diisopropylfluorophosphate
-
-
EDTA
-
1 mM, 15% inhibition
ethyl (2E)-3-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)prop-2-enoate
-
-
ethyl 2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazole-4-carboxylate
-
-
ethyl 2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4,5-dihydro-1H-imidazole-4-carboxylate
-
-
ethyl 2-methyl-3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]propanoate
-
-
ethyl 2-methyl-3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4,5-dihydro-1H-imidazol-5-yl]propanoate
-
-
ethyl 2-pyridin-4-yl-1-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)-4,5-dihydro-1H-imidazole-4-carboxylate
-
-
ethyl 2-pyridin-4-yl-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazole-4-carboxylate
-
-
ethyl 3-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]propanoate
ethyl 4-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]butanoate
ethyl 5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazole-3-carboxylate
-
-
ethyl [((5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl)carbonyl)amino]acetate
-
-
ethyl [([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]acetate
-
-
ethyl [[(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)carbamoyl]amino]acetate
-
-
iodoacetamide
-
1 mM, 16% inhibition
L-malate
-
-
malonyl-CoA
-
methyl (2E)-3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]prop-2-enoate
-
-
methyl (2E)-3-[2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]prop-2-enoate
-
-
methyl (2E)-3-[2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4,5-dihydro-1H-imidazol-5-yl]prop-2-enoate
-
-
methyl 2,2-diethyl-4-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]butanoate
-
-
methyl 2,2-diethyl-4-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]pentanoate
-
-
methyl 3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]propanoate
-
-
methyl 3-[2-(1-methylethyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4,5-dihydro-1H-imidazol-5-yl]propanoate
-
-
methyl 3-[2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-1H-imidazol-5-yl]propanoate
-
-
methyl 3-[2-(1-methylpropyl)-1-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4,5-dihydro-1H-imidazol-5-yl]propanoate
-
-
methyl 4-methyl-2-(2-methylpropyl)-2-[2-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]ethyl]pentanoate
-
-
methyl 4-[(2-methylpropanoyl)[5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-1,3-thiazol-2-yl]amino]benzoate
-
-
methyl 4-[(morpholin-4-ylcarbonyl)[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]butanoate
-
-
methyl 4-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl](morpholin-4-ylcarbonyl)amino]butanoate
-
-
methyl 5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)morpholine-4-carboxamido)pentanoate
-
-
methyl 5-[(2-methylpropanoyl)[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]pentanoate
-
-
methyl 5-[(morpholin-4-ylcarbonyl)[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]pentanoate
-
-
methyl 5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl](2-methylpropanoyl)amino]pentanoate
-
-
methyl 5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl](morpholin-4-ylcarbonyl)amino]pentanoate
-
-
methyl N-(3-phenylpropanoyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]glycinate
-
-
methyl N-(morpholin-4-ylcarbonyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-b-alaninate
-
-
methyl N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(3-phenylpropanoyl)glycinate
-
-
methyl N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(morpholin-4-ylcarbonyl)-beta-alaninate
-
-
methyl N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(morpholin-4-ylcarbonyl)glycinate
-
-
methyl [(2-methylpropanoyl)[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]acetate
-
-
methyl [(morpholin-4-ylcarbonyl)[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]acetate
-
-
methyl [[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl](2-methylpropanoyl)amino]acetate
-
-
methyl-5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl) phenyl)morpholine-4-carboxamido)pentanoate
-
i.e. CBM-301106, specific inhibitor of the enzyme
methylmalonyl-CoA
morpholin-4-yl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]methanone
-
-
morpholine-4-carboxylic acid (2-hydroxyethyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid (3-cyanopropyl)-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid butyl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid ethyl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid heptyl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid hexyl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid methyl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid octyl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
-
-
morpholine-4-carboxylic acid pentyl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid phenethyl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid propyl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
morpholine-4-carboxylic acid [4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]amide
-
-
N,2-dimethyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N,N-bis(2-methylpropyl)-4-(trifluoroacetyl)benzamide
-
-
N,N-bis(2-methylpropyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N,N-diethyl-4-(trifluoroacetyl)benzamide
-
-
N,N-diisobutyl-4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)benzamide
N,N-dipropyl-4-(trifluoroacetyl)benzamide
-
-
N-(1,3-dimethylbutyl)-4-(trifluoroacetyl)benzamide
-
-
N-(1,5-dimethylhexyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-(1-methylethyl)-3-phenyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-(1-methylethyl)-3-pyridin-4-yl-4-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)isoxazole-5-carboxamide
-
-
N-(1-methylethyl)-4-(trifluoroacetyl)benzamide
-
-
N-(1-methylethyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-(1-methylethyl)-N-(2-methylpropyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-(1-methylethyl)-N-phenyl-4-(trifluoroacetyl)benzamide
-
-
N-(1-methylhexyl)-4-(trifluoroacetyl)benzamide
-
-
N-(1-methylhexyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-(2-cyanoethyl)-N-ethyl-4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)benzamide
N-(2-cyanoethyl)-N-ethyl-4-(trifluoroacetyl)benzamide
-
-
N-(2-cyanoethyl)-N-phenoxy-4-(trifluoroacetyl)benzamide
-
-
N-(2-dimethylaminoethyl)-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isobutyramide
-
-
N-(2-hydroxyethyl)-2-methyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-(2-hydroxyethyl)-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isobutyramide
-
-
N-(2-hydroxyethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-(2-methylcyclohexyl)-4-(trifluoroacetyl)benzamide
-
-
N-(2-methylcyclopropyl)-N-propyl-4-(trifluoroacetyl)benzamide
-
-
N-(2-methylpropyl)-4-(trifluoroacetyl)benzamide
-
-
N-(2-methylpropyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-(2-phenoxyethyl)-4-(trifluoroacetyl)benzamide
-
-
N-(2-phenylethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-(3,3-dimethylbutyl)-4-(trifluoroacetyl)benzamide
-
-
N-(3,3-dimethylbutyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-(3,3-dimethylbutyl)-N-(2-methylpropyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-(3-cyanopropyl)-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]morpholine-4-carboxamide
-
-
N-(3-cyanopropyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-(3-phenoxypropyl)-4-(trifluoroacetyl)benzamide
-
-
N-(3-phenylpropanoyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]glycine
-
-
N-(3-tert-butoxypropyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
N-(4-cyanobutyl)-2-methyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-(4-cyanobutyl)-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-methylpropanamide
-
-
N-(4-cyanobutyl)-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isobutyramide
-
-
N-(4-cyanophenyl)-2-methyl-N-(5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-1,3-thiazol-2-yl)propanamide
-
-
N-(4-cyanophenyl)-3-(1-methylethyl)-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazole-5-carboxamide
-
-
N-(4-phenoxybutyl)-4-(trifluoroacetyl)benzamide
-
-
N-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)-3-phenylpropanamide
-
-
N-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)acetamide
-
-
N-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)hexanamide
-
-
N-(5-methyl-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-3-yl)pyridine-4-carboxamide
-
-
N-(6-methylheptyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-(cyclohexylmethyl)-4-(trifluoroacetyl)benzamide
-
-
N-(cyclopropylmethyl)-6-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]pyridine-3-carboxamide
-
-
N-(furan-2-ylmethyl)-4-(trifluoroacetyl)benzamide
-
-
N-benzyl-3-phenyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]propionamide
-
-
N-benzyl-3-phenyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-benzyl-N-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)benzamide
-
-
N-benzyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-phenylpropanamide
-
-
N-butyl-2-methyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-butyl-3-phenyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]propionamide
-
-
N-butyl-3-phenyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-butyl-N-(5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-1,3-thiazol-2-yl)acetamide
-
-
N-butyl-N-(5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-1,3-thiazol-2-yl)pyridine-4-carboxamide
-
-
N-butyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-methylpropanamide
-
-
N-butyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-phenylpropanamide
-
-
N-butyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]morpholine-4-carboxamide
-
-
N-butyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isobutyramide
N-butyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-cyclohexyl-3-phenyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]propionamide
N-cyclohexyl-3-phenyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-cyclohexyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-phenylpropanamide
-
-
N-ethyl-2-methyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-ethyl-3-phenyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]propionamide
-
-
N-ethyl-3-phenyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-ethyl-N-(2-hydroxy-2-methylpropyl)-4-(trifluoroacetyl)benzamide
-
-
N-ethyl-N-(2-methoxyethyl)-4-(trifluoroacetyl)benzamide
-
-
N-ethyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-methylpropanamide
-
-
N-ethyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-phenylpropanamide
-
-
N-ethyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]morpholine-4-carboxamide
-
-
N-ethyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]pyridine-4-carboxamide
-
-
N-ethyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isobutyramide
N-ethyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isonicotinamide
N-ethyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-ethyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]pyridine-4-carboxamide
-
-
N-ethylmaleimide
-
1 mM, 47% inhibition
N-heptyl-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-heptyl-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]morpholine-4-carboxamide
-
-
N-heptyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-hexyl-4-(trifluoroacetyl)benzamide
-
-
N-hexyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-isopropyl-3-phenyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]propionamide
-
-
N-methoxy-N-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)benzamide
-
-
N-methyl-2-phenoxy-N-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)acetamide
-
-
N-methyl-2-phenoxy-N-[4-(trifluoroacetyl)phenyl]acetamide
-
-
N-methyl-2-phenoxy-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]acetamide
-
-
N-methyl-3-phenyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]propionamide
-
-
N-methyl-3-phenyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-methyl-N-(1-methylethyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-methyl-N-(2-methylpropyl)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-methyl-N-(2-phenoxyethyl)-4-(trifluoroacetyl)benzamide
-
-
N-methyl-N-(4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl)pyridine-4-carboxamide
-
-
N-methyl-N-phenethyl-4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)benzamide
-
-
N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isobutyramide
N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isonicotinamide
-
-
N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]nicotinamide
-
-
N-methyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-methyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]pyridine-3-carboxamide
-
-
N-methyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]pyridine-4-carboxamide
-
-
N-octyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-pentyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-phenethyl-4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl) benzamide
-
-
N-propyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isobutyramide
N-propyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]morpholine-4-carboxamide
-
-
N-[(2-hydroxyphenoxy)methyl]-4-(trifluoroacetyl)benzamide
-
-
N-[2-(dimethylamino)ethyl]-2-methyl-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]propanamide
-
-
N-[2-(dimethylamino)ethyl]-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-methylpropanamide
-
-
N-[3,5-bis(trifluoromethyl)phenyl]-4-(trifluoroacetyl)benzamide
-
-
N-[3-(1-methylethyl)-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-5-yl]-2-phenylbutanamide
-
-
N-[3-(1-methylethyl)-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-5-yl]pentanamide
-
-
N-[3-(1-methylethyl)-4-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]isoxazol-5-yl]pyridine-4-carboxamide
-
-
N-[3-[bis(1-methylethyl)amino]-3-oxopropyl]-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazole-3-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-methyl-N-propylpropanamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-methyl-N-[4-(1H-tetrazol-5-yl)butyl]propanamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-methylpropanamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-phenoxyacetamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-phenyl-N-(propan-2-yl)propanamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-phenylpropanamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N,2-dimethylpropanamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2-hydroxyethyl)-2-methylpropanamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2-hydroxyethyl)morpholine-4-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2-phenylethyl)morpholine-4-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(3-phenylpropanoyl)glycine
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(morpholin-4-ylcarbonyl)-beta-alanine
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-hexylmorpholine-4-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-methyl-2-phenoxyacetamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-methyl-3-phenylpropanamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-methylmorpholine-4-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-methylpyridine-3-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-methylpyridine-4-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-octylmorpholine-4-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-pentylmorpholine-4-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-propylmorpholine-4-carboxamide
-
-
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]morpholine-4-carboxamide
-
-
N-[4-(1H-tetrazol-5-yl)butyl]-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isobutyramide
N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]isobutyramide
-
-
N-[4-(trifluoroacetyl)phenyl]morpholine-4-carboxamide
-
-
NAD+
-
-
p-chloromercuribenzoate
p-hydroxymercuribenzoate
palmitoyl-CoA
piperidin-1-yl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]methanone
-
-
propionyl-CoA
pyridoxal 5'-phosphate
-
partly competitive
pyrrolidin-1-yl-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)phenyl]methanone
-
-
SO42-
-
reversible
succinyl-CoA
tert-butyl (3R)-3-[(((5R)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl)carbonyl)amino]butanoate
-
-
tert-butyl (3R)-3-[(((5S)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl)carbonyl)amino]butanoate
-
-
tert-butyl (3R)-3-[((5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl)carbonyl)amino]butanoate
-
-
tert-butyl (3R)-3-[([(5R)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]butanoate
-
-
tert-butyl (3R)-3-[([(5S)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]butanoate
-
-
tert-butyl (3R)-5-methyl-3-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]hexanoate
-
-
tert-butyl (3S)-3-[(((5R)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl)carbonyl)amino]butanoate
-
-
tert-butyl (3S)-3-[(((5S)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl)carbonyl)amino]butanoate
-
-
tert-butyl (3S)-3-[((5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl)carbonyl)amino]butanoate
-
-
tert-butyl (3S)-3-[([(5R)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]butanoate
-
-
tert-butyl (3S)-3-[([(5S)-5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]butanoate
-
-
tert-butyl (3S)-3-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]butanoate
-
-
tert-butyl (3S)-5-methyl-3-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]hexanoate
-
-
tert-butyl 3-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxamido)butanoate
-
i.e. CBM-301940
tert-butyl 3-[((5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl)carbonyl)amino]butanoate
-
-
tert-butyl 3-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]propanoate
-
-
tert-butyl 5-methyl-3-[([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)amino]hexanoate
tert-butyl N-([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)-b-alaninate
-
-
tert-butyl N-([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)leucinate
-
-
tert-butyl N-([5-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]-4,5-dihydroisoxazol-3-yl]carbonyl)phenylalaninate
-
-
Vanillin
-
-
[(2-methylpropanoyl)[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]amino]acetic acid
-
-
[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl](2-methylpropanoyl)amino]acetic acid
-
-
additional information
-