4.1.1.9: malonyl-CoA decarboxylase
This is an abbreviated version!
For detailed information about malonyl-CoA decarboxylase, go to the full flat file.
Word Map on EC 4.1.1.9
-
4.1.1.9
-
carnitine
-
malonic
-
amp-activated
-
palmitoyltransferase
-
aciduria
-
goose
-
uropygial
-
methylmalonyl-coa
-
methylmalonic
-
medicine
- 4.1.1.9
- carnitine
-
malonic
-
amp-activated
- palmitoyltransferase
-
aciduria
- goose
-
uropygial
- methylmalonyl-coa
-
methylmalonic
- medicine
Reaction
Synonyms
Acyl-CoA: malonate CoA transferase/malonyl-CoA decarboxylase, Decarboxylase, malonyl coenzyme A, hMCD, malonyl CoA decarboxylase, Malonyl coenzyme A decarboxylase, Malonyl-CoA decarboxylase, malonyl-CoA decarboxylase/acetyltransferase, malonyl-coenzyme A decarboxylase, MCD, MLYCD
ECTree
Advanced search results
Posttranslational Modification
Posttranslational Modification on EC 4.1.1.9 - malonyl-CoA decarboxylase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
phosphoprotein
proteolytic modification
additional information
phosphoprotein
-
activation of AMP-activated protein kinase during muscle contraction leads to phosphorylation of MCD and an increase in its activity
-
full-length MCD contains a putative, N-terminal 39 amino acid mitochondria targeting sequence and a peroxisomal tageting sequence
proteolytic modification
-
the 50.7 kDa isoform may be generated from the 54.7 kDa isoform by posttranslational processing, probably by N-terminal cleavage
proteolytic modification
-
the N-terminal 38 amino acids represents a putative mitochondrial targeting sequence, the last 3 amino acid sequences, SKL, represent peroxisomal targeting ones
-
INS-1 MCD, sequence shows multiple possible sites of phosphorylation by casein kinase II and protein kinase C, no acylation sites
additional information
-
recombinant MCD has a different degree or lack of glycosylation from the original rat enzyme
additional information
-
the enzyme is phosphorylated at seven seryl/threonyl residues, and is acetylated at 11 lysyl residues