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4.1.1.9: malonyl-CoA decarboxylase

This is an abbreviated version!
For detailed information about malonyl-CoA decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.9

Reaction

malonyl-CoA
=
acetyl-CoA
+
CO2

Synonyms

Acyl-CoA: malonate CoA transferase/malonyl-CoA decarboxylase, Decarboxylase, malonyl coenzyme A, hMCD, malonyl CoA decarboxylase, Malonyl coenzyme A decarboxylase, Malonyl-CoA decarboxylase, malonyl-CoA decarboxylase/acetyltransferase, malonyl-coenzyme A decarboxylase, MCD, MLYCD

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.9 malonyl-CoA decarboxylase

Cloned

Cloned on EC 4.1.1.9 - malonyl-CoA decarboxylase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
cytoplasmic enzyme from uropygial gland and mitochondrial enzyme from liver
-
expressed in Bombyx mori
expressed in Escherichia coli BL21 cells
-
expressed in Escherichia coli BL21(DE3) cells
-
expressed in Escherichia coli strain BL21
-
expression in Escherichia coli
expression in the human hepatoma cell line huh7, sequencing, located on chromosome 16q24
-
expression of wild-type and mutant enzymes as maltose-binding protein fusion proteins in Escherichia coli strain BL21(DE3) in minimal medium containing selenomethionine
from brain, expression in Escherichia coli BL21, sequencing
-
from heart, overexpression of full-length and N-terminal truncated hMCD in Escherichia coli BL21 (DE3), sequencing
-
from liver, expression in COS-7 cells as 50.7 kDa and 54.7 kDa MCD isoforms, sequencing
-
from pancreatic beta cell line INS-1, expression in human kidney 293 cells, sequencing
-
gene MLYCD, localized on chromosome 16q24, DNA and amino acid sequence determination and analysis of the mutant enzyme, sequence comparison
overexpression in Escherichia coli BL21 (DE3)
overexpression of MCD lacking both its mitochondrial and peroxisomal targeting sequences in INS-1-derived 832/13 beta-cells, effect of MCD expression on glucose-stimulated insulin secretion
-
single copy gene
-