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Literature summary for 4.1.1.9 extracted from

  • Buckner, J.S.; Kolattukudy, P.E.; Poulose, A.J.
    Purification and properties of malonyl-coenzyme A decarboxylase, a regulatory enzyme from the uropygial gland of goose (1976), Arch. Biochem. Biophys., 177, 539-551.
    View publication on PubMed
Search for more literature for 4.1.1.9

Inhibitors

Inhibitors Comment Organism Structure
2,2'-dipyridyl
-
 Anser sp.
3-Bromopyruvate
-
 Anser sp.
acetyl-CoA
-
 Anser sp.
Avidin 0.6 mg/ml, 11% inhibition Anser sp.
CoA
-
 Anser sp.
EDTA 1 mM, 15% inhibition Anser sp.
methylmalonyl-CoA
-
 Anser sp.
NEM
-
 Anser sp.
p-hydroxymercuribenzoate
-
 Anser sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 malonyl-CoA
-
 Anser sp.

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no metal ion participation Anser sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47000
-
 4 * 47000, SDS-PAGE Anser sp.
186000
-
 equilibrium sedimentation Anser sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Malonyl-CoA Anser sp. discussion of the probable role of the enzyme in the regulation of lipid metabolism, especially branched-chain fatty acid synthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Anser sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Anser sp.

Source Tissue

Source Tissue Comment Organism Textmining
uropygial gland
-
 Anser sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
74
-
-
 Anser sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Malonyl-CoA
-
 Anser sp. Acetyl-CoA + CO2
-
 ?
Malonyl-CoA discussion of the probable role of the enzyme in the regulation of lipid metabolism, especially branched-chain fatty acid synthesis Anser sp. ?
-
 ?
methylmalonyl-CoA at less than 7% of the activity with malonyl-CoA Anser sp. propionyl-CoA + CO2
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 47000, SDS-PAGE Anser sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9.5
-
-
 Anser sp.