3.4.21.5: thrombin

This is an abbreviated version, for detailed information about thrombin, go to the full flat file.

Reaction

selective cleavage of Arg-/-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B =

Synonyms

activated factor II, alpha-thrombin, alphaTh, beta-thrombin, blood-coagulation factor II, activated, blood-coagulation factor IIa, clotting factor IIa, EC 3.4.4.13, factor IIa, fibrinogenase, thrombase, thrombin, E, thrombin-C, thrombofort, topical, tropostasin

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.5 thrombin

Storage Stability

Storage Stability on EC 3.4.21.5 - thrombin

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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-50C, 0.75 M NaCl, pH 6, stable for about 1 year
-
-70C, stable for at least six months
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0C, on ice, 8 h, stable
-
22C, at room temperature, several hours, stable, lyophilized stable for several months
-
4C, 0.75 M NaCl, pH 6, stable for about 1 week
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