3.4.17.2: carboxypeptidase B

This is an abbreviated version!
For detailed information about carboxypeptidase B, go to the full flat file.

Word Map on EC 3.4.17.2

3.4.17.2

cardiopulmonary

cardiac

artery

postoperative

coronary

aortic

perioperative

myocardial

pulmonary

ventricular

hemodynamic

heparin

transfusion

elective

circuit

intraoperative

valve

bleeding

hypothermic

anesthesia

venous

extracorporeal

ventilation

protamine

inotropic

cardioplegia

sternotomy

rewarming

hemodilution

revascularization

cross-clamping

atrial

normothermic

wean

hematocrit

circulatory

off-pump

analysis

cardiothoracic

synthesis

intra-aortic

medicine

open-heart

thoracotomy

in-hospital

drug development

extubation

pharmacology

crystalloid

cannulation

roller

transesophageal

fentanyl

antegrade

reoperation

diagnostics

Reaction

preferential release of a C-terminal lysine or arginine amino acid =

Synonyms

47 kDa zymogen granule membrane associated protein, aCAP, B carboxypeptidase, basic carboxypeptidase, carboxypeptidase B, Carboxypeptidase B1, carboxypeptidase B2, carboxypeptidase BII, Cbp, CPB, CPB1, CPB2, CPBAg1, cpbAs1, EC 3.4.12.3, EC 3.4.2.2, HBCPB, HzCPB, More, Pancreas-specific protein, PASP, PCB, PcpB, pp-CpB, ppCPB, protaminase, TAFI, thrombin-activatable fibrinolysis inhibitor, thrombin-activatable procarboxypeptidase B, tissue carboxypeptidase B, ZAP47

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.17 Metallocarboxypeptidases

3.4.17.2 carboxypeptidase B

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Results	in table
6	Activating Compound
39	AA Sequence
7	Application
1	CAS Registry Number
12	Cloned(Commentary)
9	Crystallization (Commentary)
6412	Disease/ Diagnostics
3	Expression
13	General Information
5	General Stability
8	IC50 Value
121	Inhibitors
1	kcat/KM [mM/s]
47	Ki Value [mM]
42	KM Value [mM]
3	Localization
21	Metals/Ions
29	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
72	Organism
90	PDB ID
31	pH Optimum
8	pH Range
8	pH Stability
15	Posttranslational Modification
3	Protein Variants
31	Purification (Commentary)
5	Reaction
2	Reaction Type
72	Reference
55	Source Tissue
17	Specific Activity [micromol/min/mg]
4	Storage Stability
91	Substrates and Products (Substrate)
14	Subunits
77	Synonyms
21	Temperature Optimum [°C]
5	Temperature Range [°C]
15	Temperature Stability [°C]
32	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 3.4.17.2 - carboxypeptidase B

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23500

27700

gel filtration

31000

1 * 31000, SDS-PAGE

32000

32210

carboxypeptidase B II, gel filtration

36375

32920

Homo sapiens

carboxypeptidase B I, gel filtration

36375

34000

3 entries

34200

Penaeus setiferus

boundary depletion equilibrium sedimentation

34300

34500

SDS-PAGE

35000

35000 - 37000

equilibrium sedimentation

36370

47000

Mus musculus

Western Blot analysis, nitrosylated CPB1

48100

calculated from cDNA

57400

equilibrium sedimentation

58000

SDS-PAGE

65000

Western blot analysis

707319

70000

Sus scrofa

Western blot analysis, investigation of peroxynitrite-induced chemical nitrosylation of CPB, dimer formation, band immunoreactive to an antibody specific to 3-nitrotyrosine

709356

9200

2 entries

additional information

2 entries