3.4.17.2: carboxypeptidase B

This is an abbreviated version!
For detailed information about carboxypeptidase B, go to the full flat file.

Word Map on EC 3.4.17.2

3.4.17.2

cardiopulmonary

cardiac

artery

postoperative

coronary

aortic

perioperative

myocardial

pulmonary

ventricular

hemodynamic

heparin

transfusion

elective

circuit

intraoperative

valve

bleeding

hypothermic

anesthesia

venous

extracorporeal

ventilation

protamine

inotropic

cardioplegia

sternotomy

rewarming

hemodilution

revascularization

cross-clamping

atrial

normothermic

wean

hematocrit

circulatory

off-pump

analysis

cardiothoracic

synthesis

intra-aortic

medicine

open-heart

thoracotomy

in-hospital

drug development

extubation

pharmacology

crystalloid

cannulation

roller

transesophageal

fentanyl

antegrade

reoperation

diagnostics

Reaction

preferential release of a C-terminal lysine or arginine amino acid =

Synonyms

47 kDa zymogen granule membrane associated protein, aCAP, B carboxypeptidase, basic carboxypeptidase, carboxypeptidase B, Carboxypeptidase B1, carboxypeptidase B2, carboxypeptidase BII, Cbp, CPB, CPB1, CPB2, CPBAg1, cpbAs1, EC 3.4.12.3, EC 3.4.2.2, HBCPB, HzCPB, More, Pancreas-specific protein, PASP, PCB, PcpB, pp-CpB, ppCPB, protaminase, TAFI, thrombin-activatable fibrinolysis inhibitor, thrombin-activatable procarboxypeptidase B, tissue carboxypeptidase B, ZAP47

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.17 Metallocarboxypeptidases

3.4.17.2 carboxypeptidase B

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Results	in table
6	Activating Compound
39	AA Sequence
7	Application
1	CAS Registry Number
12	Cloned(Commentary)
9	Crystallization (Commentary)
6412	Disease/ Diagnostics
3	Expression
13	General Information
5	General Stability
8	IC50 Value
121	Inhibitors
1	kcat/KM [mM/s]
47	Ki Value [mM]
42	KM Value [mM]
3	Localization
21	Metals/Ions
29	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
72	Organism
90	PDB ID
31	pH Optimum
8	pH Range
8	pH Stability
15	Posttranslational Modification
3	Protein Variants
31	Purification (Commentary)
5	Reaction
2	Reaction Type
72	Reference
55	Source Tissue
17	Specific Activity [micromol/min/mg]
4	Storage Stability
91	Substrates and Products (Substrate)
14	Subunits
77	Synonyms
21	Temperature Optimum [°C]
5	Temperature Range [°C]
15	Temperature Stability [°C]
32	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 3.4.17.2 - carboxypeptidase B

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0.0000055

(2S)-7-amino-2-[(hydroxy[(1R)-2-methyl-1-[(3-phenylpropanoyl)amino]propyl]phosphoryl)methyl]heptanoic acid

Sus scrofa

P09955

pH and temperature not specified in the publication

732306

0.000002

(R)-2-(3-guanidinophenyl)-3-mercaptopropanoic acid

Sus scrofa

P09955

707593

0.0023

(R)-2-guanidino-3-mercaptopropanoic acid

Sus scrofa

P09955

707593

0.000024

2-(4-(furan-2-ylmethyl)-5-(4-hydroxyphenyl)-4H-1,2,4-triazol-3-ylthio)-1-(thiophen-2-yl)ethanone

Sus scrofa

P09955

707593

0.000000025

3-(6-amino-5-chloropyridin-3-yl)-2-(selanylmethyl)propanoic acid

Sus scrofa

P09955

pH and temperature not specified in the publication

732306

0.000002

7-amino-2-(selanylmethyl)heptanoic acid

Sus scrofa

P09955

pH and temperature not specified in the publication

732306

0.000034

7-amino-2-(sulfanylmethyl)heptanoic acid

Sus scrofa

P09955

pH and temperature not specified in the publication

732306

0.0000011

7-amino-2-[(propanoylselanyl)methyl]heptanoic acid

Sus scrofa

P09955

pH and temperature not specified in the publication

732306