3.4.17.2: carboxypeptidase B
This is an abbreviated version!
For detailed information about carboxypeptidase B, go to the full flat file.
Word Map on EC 3.4.17.2
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3.4.17.2
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cardiopulmonary
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cardiac
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artery
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postoperative
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coronary
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aortic
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perioperative
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myocardial
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pulmonary
-
ventricular
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hemodynamic
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heparin
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transfusion
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elective
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circuit
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intraoperative
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valve
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bleeding
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hypothermic
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anesthesia
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venous
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extracorporeal
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ventilation
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protamine
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inotropic
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cardioplegia
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sternotomy
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rewarming
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hemodilution
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revascularization
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cross-clamping
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atrial
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normothermic
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wean
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hematocrit
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circulatory
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off-pump
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analysis
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cardiothoracic
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synthesis
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intra-aortic
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medicine
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open-heart
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thoracotomy
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in-hospital
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drug development
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extubation
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pharmacology
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crystalloid
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cannulation
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roller
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transesophageal
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fentanyl
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antegrade
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reoperation
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diagnostics
- 3.4.17.2
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cardiopulmonary
- cardiac
- artery
-
postoperative
- coronary
- aortic
-
perioperative
- myocardial
- pulmonary
- ventricular
-
hemodynamic
- heparin
-
transfusion
-
elective
-
circuit
-
intraoperative
- valve
-
bleeding
-
hypothermic
-
anesthesia
- venous
-
extracorporeal
-
ventilation
- protamine
-
inotropic
-
cardioplegia
-
sternotomy
-
rewarming
-
hemodilution
-
revascularization
-
cross-clamping
- atrial
-
normothermic
-
wean
-
hematocrit
-
circulatory
-
off-pump
- analysis
-
cardiothoracic
- synthesis
-
intra-aortic
- medicine
-
open-heart
-
thoracotomy
-
in-hospital
- drug development
-
extubation
- pharmacology
- crystalloid
-
cannulation
-
roller
-
transesophageal
-
fentanyl
-
antegrade
-
reoperation
- diagnostics
Reaction
preferential release of a C-terminal lysine or arginine amino acid =
Synonyms
47 kDa zymogen granule membrane associated protein, aCAP, B carboxypeptidase, basic carboxypeptidase, carboxypeptidase B, Carboxypeptidase B1, carboxypeptidase B2, carboxypeptidase BII, Cbp, CPB, CPB1, CPB2, CPBAg1, cpbAs1, EC 3.4.12.3, EC 3.4.2.2, HBCPB, HzCPB, More, Pancreas-specific protein, PASP, PCB, PcpB, pp-CpB, ppCPB, protaminase, TAFI, thrombin-activatable fibrinolysis inhibitor, thrombin-activatable procarboxypeptidase B, tissue carboxypeptidase B, ZAP47
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Application
Application on EC 3.4.17.2 - carboxypeptidase B
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analysis
diagnostics
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the enzyme is a serum marker for acute pancreatitis and pancreatic graft injection
drug development
the enzyme is a target for design of active site inhibitors based on the structure of tick carboxypeptidase inhibitor, a potential antithrombolytic drug
medicine
cpbAs1 can be introduced as a transmission-blocking vaccine candidate in regions where Anopheles stephensi is the main malaria vector
pharmacology
carboxypeptidase B is commonly used in the industrial insulin production and as a template for drug design
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the immobilized carboxypeptidase B is used for stepwise digestion of cytochrome c
analysis
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carboxypeptidase B treatment of recombinant monoclonal antibodies indicates that C-terminal lysine variants are present mainly among the basic species but also to some extent among the acidic species