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Literature summary for 3.4.17.2 extracted from

  • Brodrick, J.W.; Geokas, M.C.; Largman, C.
    Human carboxypeptidase B. II. Purification of the enzyme from pancreatic tissue and comparison with the enzymes present in pancreatic secretion (1976), Biochim. Biophys. Acta, 452, 468-481.
    View publication on PubMed
Search for more literature for 3.4.17.2

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.18
-
 hippuryl-L-Arg carboxypeptidase B I Homo sapiens
0.19
-
 hippuryl-L-Arg carboxypeptidase B Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
9200
-
 x * 9200 + x * 23500, carboxypeptidase B I, SDS-PAGE after reduction with 2-mercaptoethanol Homo sapiens
23500
-
 x * 9200 + x * 23500, carboxypeptidase B I, SDS-PAGE after reduction with 2-mercaptoethanol Homo sapiens
34000
-
 1 * 34000, carboxypeptidase B, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
pancreas carboxypeptidase B from pancreatic tissue, carboxypeptidase B I and B II from pancreatic juice. Carboxypeptidase B is converted to carboxypeptidase B II by trypsin Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hippuryl-L-Arg
-
 Homo sapiens hippuric acid + L-Arg
-
 ?

Subunits

Subunits Comment Organism
dimer x * 9200 + x * 23500, carboxypeptidase B I, SDS-PAGE after reduction with 2-mercaptoethanol Homo sapiens
monomer 1 * 34000, carboxypeptidase B, SDS-PAGE Homo sapiens