Reference on EC 4.6.1.1 - adenylate cyclase and Organism(s) Rattus norvegicus and UniProt Accession P40146
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kornblihtt, A.R.; Flawia, M.M.; Torres, H.N.
Manganese ion dependent adenylate cyclase activity in rat testes: purification and properties
Biochemistry
20
1262-1267
1981
Rattus norvegicus
Rodan, S.B.; Egan, J.J.; Golub, E.E.; Rodan, G.A.
Comparison of bone and osteosarcoma adenylate cyclase. Partial purification of membranes and kinetic properties of enzyme
Biochem. J.
185
617-627
1980
Rattus norvegicus
Stengel, D.; Hanoune, J.
Solubilization and physical characterization of the adenylate cyclase from rat-liver plasma membranes
Eur. J. Biochem.
102
21-34
1979
Rattus norvegicus
Neer, E.J.
Physical and functional properties of adenylate cyclase from mature rat testis
J. Biol. Chem.
253
5808-5812
1978
Rattus norvegicus
Braun, T.
Purification of soluble form of adenylyl cyclase from testes
Methods Enzymol.
195
130-136
1991
Rattus norvegicus
Neer, E.J.
The size of adenylate cyclase
J. Biol. Chem.
249
6527-6531
1974
Rattus norvegicus
Feinstein, P.G.; Schrader, K.A.; Bakalyar, H.A.; Tang, W-J.; Krupinski, J.; Gilman, A.G.; Reed, R.R.
Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain
Proc. Natl. Acad. Sci. USA
88
10173-10177
1991
Rattus norvegicus
Premont, R.T.; Matsuoka, I.; Mattei, M.G.; Pouille, Y.; Defer, N.; Hanoune, J.
Identification and characterization of a widely expressed form of adenylyl cyclase
J. Biol. Chem.
271
13900-13907
1996
Rattus norvegicus, Mus musculus (P51830), Mus musculus
Sethi, R.; Dhalla, K.S.; Shah, K.R.; Dhalla, N.S.
Characterization of adenylyl cyclase in heart sarcolemma in the absence or presence of alamethicin
Mol. Cell. Biol.
119
185-193
1993
Rattus norvegicus
Plesneva, S.A.; Nalivaeva, N.N.; Zhuravin, I.A.
Adenylate cyclase system of the rat striatum: regulatory properties and the effects of gangliosides
Neurosci. Behav. Physiol.
28
392-396
1998
Rattus norvegicus
Enomoto, L.; Takano, M.; Ariyoshi, S.; Asakawa, T.
Mechanism and properties of inhibition of purified rat brain adenylate cyclase by G protein beta gamma-subunits
Jpn. J. Pharmacol.
69
239-250
1995
Rattus norvegicus
Pozo, D.; Segura, J.J.; Carrero, I.; Guijarro, L.G.; Prieto, J.C.; Calvo, J.R.
Characterization of adenylyl cyclase stimulated by VIP in rat and mouse peritoneal macrophage membranes
Biochim. Biophys. Acta
1312
249-254
1996
Mus musculus, Rattus norvegicus
Nair, B.G.; Patel, T.B.
Inhibition of hepatic adenylate cyclase by NADH
Life Sci.
49
915-923
1991
Rattus norvegicus
Defer, N.; Best-Belpomme, M.; Hanoune, J.
Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase
Am. J. Physiol.
279
F400-F416
2000
Gallus gallus, Mus musculus, Rattus norvegicus
Jaiswal, B.S.; Conti, M.
Identification and functional analysis of splice variants of the germ cell soluble adenylyl cyclase
J. Biol. Chem.
276
31698-31708
2001
Mus musculus, Rattus norvegicus
Hatley, M.E.; Gilman, A.G.; Sunahara, R.K.
Expression, purification, and assay of cytosolic (catalytic) domains of membrane-bound mammalian adenylyl cyclases
Methods Enzymol.
345
127-140
2001
Canis lupus familiaris, Rattus norvegicus
Buck, J.; Sinclair, M.L.; Schapal, L.; Cann, M.J.; Levin, L.R.
Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals
Proc. Natl. Acad. Sci. USA
96
79-84
1999
Rattus norvegicus (Q9Z286)
Tesmer, J.J.G.; Sunahara, R.K.; Johnson, R.A.; Gosselin, G.; Gilman, A.G.; Sprang, S.R.
Two-metal-ion catalysis in adenylyl cyclase
Science
285
756-760
1999
Rattus norvegicus
Yoshimura, M.; Pearson, S.; Kadota, Y.; Gonzalez, C.E.
Identification of ethanol responsive domains of adenylyl cyclase
Alcohol. Clin. Exp. Res.
30
1824-1832
2006
Rattus norvegicus (P21932), Rattus norvegicus (P26769), Homo sapiens (P51828)
Paunescu, T.G.; Da Silva, N.; Russo, L.M.; McKee, M.; Lu, H.A.; Breton, S.; Brown, D.
Association of soluble adenylyl cyclase with the V-ATPase in renal epithelial cells
Am. J. Physiol. Renal Physiol.
294
F130-F138
2008
Mus musculus, Rattus norvegicus
Wang, S.C.; Lai, H.L.; Chiu, Y.T.; Ou, R.; Huang, C.L.; Chern, Y.
Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor
Biochem. J.
406
383-388
2007
Rattus norvegicus (Q04400)
Linder, J.U.
Class III adenylyl cyclases: molecular mechanisms of catalysis and regulation
Cell. Mol. Life Sci.
63
1736-1751
2006
Bacillus anthracis, Bordetella pertussis, Saccharomyces cerevisiae, Caenorhabditis elegans, Chlamydomonas reinhardtii, Chloroflexus aurantiacus, Dictyostelium discoideum, Drosophila melanogaster, Escherichia coli, Euglena gracilis, Mus musculus, Myxococcus xanthus, Pseudomonas aeruginosa, Rattus norvegicus, Sinorhizobium meliloti, Schizosaccharomyces pombe, Arthrospira platensis, Trypanosoma brucei, Ustilago maydis, Yersinia enterocolitica, Mycobacterium tuberculosis (P9WQ35), Nostoc sp. PCC 7120 = FACHB-418 (Q7A2D9), Nostoc sp. PCC 7120 = FACHB-418 (Q8YMH0), Nostoc sp. PCC 7120 = FACHB-418 (Q8YVS0), Mycobacterium tuberculosis H37Rv (P9WQ35)
Gros, R.; Ding, Q.; Chorazyczewski, J.; Pickering, J.G.; Limbird, L.E.; Feldman, R.D.
Adenylyl cyclase isoform-selective regulation of vascular smooth muscle proliferation and cytoskeletal reorganization
Circ. Res.
99
845-852
2006
Rattus norvegicus
Beazely, M.A.; Watts, V.J.
Regulatory properties of adenylate cyclases type 5 and 6: A progress report
Eur. J. Pharmacol.
535
1-12
2006
Cricetulus griseus, Homo sapiens, Mus musculus, Rattus norvegicus, Sus scrofa
Gao, X.; Sadana, R.; Dessauer, C.W.; Patel, T.B.
Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits
J. Biol. Chem.
282
294-302
2007
Canis lupus familiaris, Homo sapiens, Rattus norvegicus
Nawoschik, S.P.; Olsen, M.; Smith, D.L.; Khawaja, X.
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line
J. Pharmacol. Toxicol. Methods
55
323-331
2007
Rattus norvegicus
Watts, V.J.
Adenylyl cyclase isoforms as novel therapeutic targets: an exciting example of excitotoxicity neuroprotection
Mol. Interv.
7
70-73
2007
Mus musculus, Rattus norvegicus
Mou, T.C.; Gille, A.; Suryanarayana, S.; Richter, M.; Seifert, R.; Sprang, S.R.
Broad specificity of mammalian adenylyl cyclase for interaction with 2,3-substituted purine- and pyrimidine nucleotide inhibitors
Mol. Pharmacol.
70
878-886
2006
Canis lupus familiaris, Rattus norvegicus
Antoni, F.A.; Wiegand, U.K.; Black, J.; Simpson, J.
Cellular localisation of adenylyl cyclase: a post-genome perspective
Neurochem. Res.
31
287-295
2006
Homo sapiens, Macaca sp., Mus musculus, Rattus norvegicus, Mus musculus C57BL/6
Willoughby, D.; Cooper, D.M.
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains
Physiol. Rev.
87
965-1010
2007
Aplysia sp., Canis lupus familiaris, Oryctolagus cuniculus, Dictyostelium discoideum, Drosophila sp. (in: flies), Homo sapiens, Mus musculus, Paramecium sp., Rattus norvegicus, Tetrahymena sp., Plasmodium sp.
Sinha, S.C.; Sprang, S.R.
Structure, mechanism, regulation and evolution of class III nucleotidyl cyclases
Rev. Physiol. Biochem. Pharmacol.
157
105-140
2007
Aeromonas hydrophila, Bacillus anthracis, Prevotella ruminicola, Bordetella pertussis, Canis lupus familiaris, Caulobacter vibrioides, Escherichia sp., Haemophilus sp., Mycobacterium tuberculosis, Yersinia pestis, Pseudomonas sp., Pseudomonas aeruginosa, Rattus norvegicus, Rhizobium etli, Sinorhizobium meliloti, Arthrospira platensis, Trypanosoma brucei, Vibrio parahaemolyticus, Yersinia sp.
Li, Y.; Descorbeth, M.; Anand-Srivastava, M.B.
Role of oxidative stress in high glucose-induced decreased expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells
Am. J. Physiol. Heart Circ. Physiol.
294
H2845-H2854
2008
Rattus norvegicus
Lee, C.B.; Koh, H.C.
Modification of the cardiovascular response of posterior hypothalamic adenosine A(2A) receptor stimulation by adenylate cyclase and KATP channel blockade in anesthetized rats
Auton. Neurosci.
146
70-75
2009
Rattus norvegicus
Slotkin, T.A.; Ryde, I.T.; Mackillop, E.A.; Bodwell, B.E.; Seidler, F.J.
Adolescent nicotine administration changes the responses to nicotine given subsequently in adulthood: adenylyl cyclase cell signaling in brain regions during nicotine administration and withdrawal, and lasting effects
Brain Res. Bull.
76
522-530
2008
Rattus norvegicus
Wann, B.P.; DAnjou, B.; Bah, T.M.; Webster, H.H.; Godbout, R.; Rousseau, G.
Effect of olfactory bulbectomy on adenylyl cyclase activity in the limbic system
Brain Res. Bull.
79
32-36
2009
Homo sapiens, Rattus norvegicus
Costa, L.; Santangelo, F.; Li Volsi, G.; Ciranna, L.
Modulation of AMPA receptor-mediated ion current by pituitary adenylate cyclase-activating polypeptide (PACAP) in CA1 pyramidal neurons from rat hippocampus
Hippocampus
19
99-109
2009
Rattus norvegicus
Gao, M.H.; Tang, T.; Guo, T.; Miyanohara, A.; Yajima, T.; Pestonjamasp, K.; Feramisco, J.R.; Hammond, H.K.
Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes
J. Biol. Chem.
283
33527-33535
2008
Mus musculus, Rattus norvegicus
Hallows, K.R.; Wang, H.; Edinger, R.S.; Butterworth, M.B.; Oyster, N.M.; Li, H.; Buck, J.; Levin, L.R.; Johnson, J.P.; Pastor-Soler, N.M.
Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells
J. Biol. Chem.
284
5774-5783
2009
Rattus norvegicus (Q9Z286)
Ramos, L.S.; Zippin, J.H.; Kamenetsky, M.; Buck, J.; Levin, L.R.
Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells
J. Gen. Physiol.
132
329-338
2008
Rattus norvegicus
Schlicker, C.; Rauch, A.; Hess, K.C.; Kachholz, B.; Levin, L.R.; Buck, J.; Steegborn, C.
Structure-based development of novel adenylyl cyclase inhibitors
J. Med. Chem.
51
4456-4464
2008
Rattus norvegicus, Arthrospira platensis (O32393), Homo sapiens (Q96PN6), Homo sapiens
Moore, S.W.; Lai Wing Sun, K.; Xie, F.; Barker, P.A.; Conti, M.; Kennedy, T.E.
Soluble adenylyl cyclase is not required for axon guidance to netrin-1
J. Neurosci.
28
3920-3924
2008
Mus musculus (Q8C0T9), Rattus norvegicus (Q9Z286)
Moulder, K.L.; Jiang, X.; Chang, C.; Taylor, A.A.; Benz, A.M.; Conti, A.C.; Muglia, L.J.; Mennerick, S.
A specific role for Ca2+-dependent adenylyl cyclases in recovery from adaptive presynaptic silencing
J. Neurosci.
28
5159-5168
2008
Mus musculus, Rattus norvegicus
Davis-Taber, R.; Baker, S.; Lehto, S.G.; Zhong, C.; Surowy, C.S.; Faltynek, C.R.; Scott, V.E.; Honore, P.
Central pituitary adenylate cyclase 1 receptors modulate nociceptive behaviors in both inflammatory and neuropathic pain states
J. Pain
9
449-456
2008
Rattus norvegicus
Vonk, A.; Reinart, R.; Rinken, A.
Modulation of adenylyl cyclase activity in rat striatal homogenate by dopaminergic receptors
J. Pharmacol. Sci.
108
63-70
2008
Rattus norvegicus
Gao, J.; Zhang, L.; Wang, Y.; Lu, B.; Cui, H.; Fu, W.; Wang, H.; Yu, Y.; Yu, X.
Antiarrhythmic effect of acupuncture pretreatment in rats subjected to simulative global ischemia and reperfusion - involvement of adenylate cyclase, protein kinase a, and L-type ca(2+) channel
J. Physiol. Sci.
58
389-396
2008
Rattus norvegicus
Lomovatskaya, L.A.; Romanenko, A.S.; Filinova, N.V.
Plant adenylate cyclases
J. Recept. Signal Transduct. Res.
28
531-542
2008
Euglena gracilis, Medicago sativa, Nicotiana tabacum, Solanum tuberosum, Bryum argenteum, Rattus norvegicus (Q9Z286)
Farrell, S.R.; Howlett, S.E.
The age-related decrease in catecholamine sensitivity is mediated by ss(1)-adrenergic receptors linked to a decrease in adenylate cyclase activity in ventricular myocytes from male Fischer 344 rats
Mech. Ageing Dev.
129
735-744
2008
Rattus norvegicus
Martin, A.C.; Willoughby, D.; Ciruela, A.; Ayling, L.J.; Pagano, M.; Wachten, S.; Tengholm, A.; Cooper, D.M.
Capacitative Ca2+ entry via Orai1 and STIM1 regulates adenylyl cyclase type 8
Mol. Pharmacol.
75
830-842
2009
Mus musculus, Rattus norvegicus (P40146)
Sanchez, G.; Colettis, N.; Vazquez, P.; Cervenansky, C.; Aguirre, A.; Quillfeldt, J.A.; Jerusalinsky, D.; Kornisiuk, E.
Muscarinic inhibition of hippocampal and striatal adenylyl cyclase is mainly due to the M(4) receptor
Neurochem. Res.
34
1363-1371
2009
Rattus norvegicus
Mostany, R.; Diaz, A.; Valdizan, E.M.; Rodriguez-Munoz, M.; Garzon, J.; Hurle, M.A.
Supersensitivity to mu-opioid receptor-mediated inhibition of the adenylyl cyclase pathway involves pertussis toxin-resistant Galpha protein subunits
Neuropharmacology
54
989-997
2008
Rattus norvegicus
Farrell, J.; Ramos, L.; Tresguerres, M.; Kamenetsky, M.; Levin, L.R.; Buck, J.
Somatic soluble adenylyl cyclase isoforms are unaffected in Sacy tm1Lex/Sacy tm1Lex knockout mice
PLoS ONE
3
e3251
2008
Rattus norvegicus
Piggott, L.A.; Bauman, A.L.; Scott, J.D.; Dessauer, C.W.
The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain
Proc. Natl. Acad. Sci. USA
105
13835-13840
2008
Rattus norvegicus
Bennun, A.
Characterization of the norepinephrine-activation of adenylate cyclase suggests a role in memory affirmation pathways Overexposure to epinephrine inactivates adenylate cyclase, a causal pathway for stress-pathologies
BioSystems
100
87-93
2010
Rattus norvegicus
Liou, J.T.; Liu, F.C.; Mao, C.C.; Hsin, S.T.; Lui, P.W.
Adenylate cyclase inhibition attenuates neuropathic pain but lacks pre-emptive effects in rats
Can. J. Anesth.
56
763-769
2009
Rattus norvegicus
Latini, S.; Chiarpotto, M.; Muciaccia, B.; Vaccari, S.; Barberi, M.; Guglielmo, M.C.; Stefanini, M.; Cecconi, S.; Canipari, R.
Inhibitory effect of pituitary adenylate cyclase activating polypeptide on the initial stages of rat follicle development
Mol. Cell. Endocrinol.
320
34-44
2010
Rattus norvegicus
Mato, S.; Vidal, R.; Castro, E.; Diaz, A.; Pazos, A.; Valdizan, E.M.
Long-term fluoxetine treatment modulates cannabinoid type 1 receptor-mediated inhibition of adenylyl cyclase in the rat prefrontal cortex through 5-hydroxytryptamine 1A receptor-dependent mechanisms
Mol. Pharmacol.
77
424-434
2010
Rattus norvegicus
Tupal, S.; Faingold, C.
Inhibition of adenylyl cyclase in amygdala blocks the effect of audiogenic seizure kindling in genetically epilepsy-prone rats
Neuropharmacology
59
107-111
2010
Rattus norvegicus
Gao, M.H.; Tang, T.; Lai, N.C.; Miyanohara, A.; Guo, T.; Tang, R.; Firth, A.L.; Yuan, J.X.; Hammond, H.K.
Beneficial effects of adenylyl cyclase type 6 (AC6) expression persist using a catalytically inactive AC6 mutant
Mol. Pharmacol.
79
381-388
2011
Rattus norvegicus
Imber, A.N.; Santin, J.M.; Graham, C.D.; Putnam, R.W.
A HCO3--dependent mechanism involving soluble adenylyl cyclase for the activation of Ca2+ currents in locus coeruleus neurons
Biochim. Biophys. Acta
1842
2569-2578
2014
Rattus norvegicus
