Activating Compound | Comment | Organism | Structure |
---|---|---|---|
G-protein | - |
Rattus norvegicus | |
glucagon-like peptide-1 | stimulates the enzyme via activation of the specific G protein-coupled receptor GLP-1 | Rattus norvegicus | |
glucose | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | Rattus norvegicus | the soluble adenylyl cyclase is the main producer of glucose-induced cAMP in INS-1E insulinoma cells, while the transmembrane adenylyl cyclase does not play a role, overview | 3',5'-cyclic-AMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
INS-1E cell | - |
Rattus norvegicus | - |
insulinoma cell | - |
Rattus norvegicus | - |
pancreatic beta cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | - |
Rattus norvegicus | 3',5'-cyclic-AMP + diphosphate | - |
? | |
ATP | the soluble adenylyl cyclase is the main producer of glucose-induced cAMP in INS-1E insulinoma cells, while the transmembrane adenylyl cyclase does not play a role, overview | Rattus norvegicus | 3',5'-cyclic-AMP + diphosphate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Rattus norvegicus |