Reference on EC 2.3.1.41 - beta-ketoacyl-[acyl-carrier-protein] synthase I and Organism(s) Escherichia coli and UniProt Accession P0A953
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Vagelos, R.P.
Acyl group transfer (acyl carrier protein)
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
8
155-199
1973
Clostridium kluyveri, Escherichia coli
-
Prescott, D.J.; Vagelos, P.R.
Acyl carrier protein
Adv. Enzymol. Relat. Areas Mol. Biol.
36
269-311
1972
Escherichia coli
Toomey, R.E.; Wakil, S.J.
Studies on the mechanism of fatty acid synthesis. XVI. Preparation and general properties of acyl-malonyl acyl carrier protein-condensing enzyme from Escherichia coli
J. Biol. Chem.
241
1159-1165
1966
Escherichia coli
Alberts, A.W.; Majerus, P.W.; Vagelos, P.R.
beta-Ketoacyl acyl carrier protein synthase
Methods Enzymol.
14
57-60
1969
Escherichia coli
-
Garwin, J.L.; Klages, A.L.; Cronan, J.E.
Structural, enzymatic, and genetic studies of beta-ketoacyl-acyl carrier protein synthases I and II of Escherichia coli
J. Biol. Chem.
255
11949-11956
1980
Escherichia coli
Alberts, A.W.; Bell, R.M.; Vagelos, P.R.
Acyl carrier protein. XV. Studies of beta-ketoacyl-acyl carrier protein synthetase
J. Biol. Chem.
247
3190-3198
1972
Escherichia coli
D'Agnolo, G.; Rosenfeld, I.S.; Vagelos, P.R.
beta-Ketoacyl-acyl carrier protein synthetase. Characterization of the acyl-enzyme intermediate
J. Biol. Chem.
250
5283-5288
1975
Escherichia coli
D'Agnolo, G.; Rosenfeld, I.S.; Vagelos, P.R.
Multiple forms of beta-ketoacyl-acyl carrier protein synthetase in Escherichia coli
J. Biol. Chem.
250
5289-5294
1975
Escherichia coli, Escherichia coli B / ATCC 11303
Verwoert, I.I.G.S.; van der Linden, K.H.; Walsh, M.C.; Nijkamp, H.J.J.; Stuitje, A.R.
Modification of Brassica napus seed oil by expression of the Escherichia coli fabH gene, encoding 3-ketoacyl-acyl carrier protein synthase III
Plant Mol. Biol.
27
875-886
1995
Brassica napus, Escherichia coli
Choi, K.H.; Heath, R.J.; Rock, C.O.
beta-ketoacyl-acyl carrier protein synthase III (FabH) is a determining factor in branched-chain fatty acid biosynthesis
J. Bacteriol.
182
365-370
2000
Bacillus subtilis, Escherichia coli
Khandekar, S.S.; Gentry, D.R.; Van Aller, G.S.; Warren, P.; Xiang, H.; Silverman, C.; Doyle, M.L.; Chambers, P.A.; Konstantinidis, A.K.; Brandt, M.; Daines, R.A.; Lonsdale, J.T.
Identification, substrate specificity, and inhibition of the Streptococcus pneumoniae beta-ketoacyl-acyl carrier protein synthase III (FabH)
J. Biol. Chem.
276
30024-30030
2001
Escherichia coli, Haemophilus influenzae, Streptococcus pneumoniae (P0A3C5)
Price, A.C.; Choi, K.H.; Heath, R.J.; Li, Z.; White, S.W.; Rock, C.O.
Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism
J. Biol. Chem.
276
6551-6559
2001
Escherichia coli
McGuire, K.A.; Siggaard-Andersen, M.; Bangera, M.G.; Olsen, J.G.; von Wettstein-Knowles, P.
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket
Biochemistry
40
9836-9845
2001
Escherichia coli
Kursula, P.; Sikkilae, H.; Fukao, T.; Kondo, N.; Wierenga, R.K.
High resolution crystal structures of human cytosolic thiolase (CT): A comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I
J. Mol. Biol.
347
189-201
2005
Escherichia coli (P0A953), Escherichia coli
Dawe, J.H.; Porter, C.T.; Thornton, J.M.; Tabor, A.B.
A template search reveals mechanistic similarities and differences in beta-ketoacyl synthases (KAS) and related enzymes
Proteins
52
427-435
2003
Escherichia coli
von Wettstein-Knowles, P.; Olsen, J.G.; McGuire, K.A.; Henriksen, A.
Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases
FEBS J.
273
695-710
2006
Escherichia coli
Feng, Y.; Cronan, J.E.
Escherichia coli unsaturated fatty acid synthesis: complex transcription of the fabA gene and in vivo identification of the essential reaction catalyzed by FabB
J. Biol. Chem.
284
29526-29535
2009
Escherichia coli
Borgaro, J.; Chang, A.; MacHutta, C.; Zhang, X.; Tonge, P.
Substrate recognition by beta-ketoacyl-ACP synthases
Biochemistry
50
10678-10686
2011
Escherichia coli, Mycobacterium tuberculosis
Lee, J.; Jeong, K.; Lee, J.; Kang, D.; Kim, Y.
In silico screening of a novel inhibitor of beta-ketoacyl acyl carrier protein synthase i
Bull. Korean Chem. Soc.
32
1645-1649
2011
Escherichia coli, Escherichia coli (E2QPI4)
-
Sabbagh, G.; Berakdar, N.
Docking studies of flavonoid compounds as inhibitors of beta-ketoacyl acyl carrier protein synthase I (Kas I) of Escherichia coli
J. Mol. Graph. Model.
61
214-223
2015
Escherichia coli (E2QPI4), Escherichia coli