6.3.5.5: carbamoyl-phosphate synthase (glutamine-hydrolysing)

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For detailed information about carbamoyl-phosphate synthase (glutamine-hydrolysing), go to the full flat file.

Reaction

2 ATP +

Synonyms

CAD, CAD carbamoyl-phosphate synthetase, CAD protein, Carbamoyl phosphate synthase (glutamine), carbamoyl phosphate synthetase, Carbamoyl phosphate synthetase (glutamine-hydrolyzing), carbamoyl phosphate synthetase 1, carbamoyl phosphate synthetase II, carbamoyl phosphate synthetase III, carbamoyl-phosphate synthetase, Carbamoyl-phosphate synthetase (glutamine-hydrolysing), carbamoyl-phosphate synthetase 2, Carbamoylphosphate synthase, Carbamoylphosphate synthetase, Carbamoylphosphate synthetase II, Carbamyl phosphate synthetase (glutamine), Carbamyl phosphate sythetase II, carbamylphosphate synthetase - aspartate transcarbamylase, CPA2, CPS, CPS II (glutamine-dependent), CPS III, CPS III (glutamine- and N-acetyl-L-glutamine-dependent), CPS1, CPSase, CPSase type II, CPSase-A, CPSase-P, CPSII, EC 2.7.2.9, Glutamine-dependent carbamyl phosphate synthetase, glutamine-hydrolyzing CPSase, MGG_04503, More, MtCPSs1, MtCPSs2, Synthase, carbamoylphosphate (glutamine), Synthetase, carbamoylphosphate (glutamine-hydrolyzing)

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor

                6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)

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Results	in table
66	Activating Compound
87162	AA Sequence
2	Application
1	CAS Registry Number
28	Cloned(Commentary)
22	Cofactor
8	Crystallization (Commentary)
76	Disease/ Diagnostics
3	Expression
9	General Information
2	General Stability
4	IC50 Value
100	Inhibitors
3	Ki Value [mM]
200	KM Value [mM]
14	Localization
21	Metals/Ions
43	Molecular Weight [Da]
56	Natural Substrates/ Products (Substrates)
490	Organism
1	Oxidation Stability
12	Pathway
91	PDB ID
17	pH Optimum
2	pH Range
1	pH Stability
5	Posttranslational Modification
209	Protein Variants
28	Purification (Commentary)
27	Reaction
3	Reaction Type
137	Reference
36	Source Tissue
17	Specific Activity [micromol/min/mg]
2	Storage Stability
219	Substrates and Products (Substrate)
46	Subunits
73	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
3	Temperature Stability [°C]
145	Turnover Number [1/s]

Expression

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Expression on EC 6.3.5.5 - carbamoyl-phosphate synthase (glutamine-hydrolysing)

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

accumulation of CPSase gene transcripts is highly reduced following seedling incubation with uridine

Medicago truncatula

B9V284

715106

carB expression is partly downregulated by ammonium treatment, while carA expression is unaffected

Arabidopsis thaliana

-

697908

mRNA levels of MtCPSs1 and MtCPSs2 are significantly increased after supplying plants with ornithine alone or in combination with uridine or arginine compared to plants treated with only uridine or arginine, respectively

Medicago truncatula

B9V284

715106