6.3.5.5: carbamoyl-phosphate synthase (glutamine-hydrolysing)

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For detailed information about carbamoyl-phosphate synthase (glutamine-hydrolysing), go to the full flat file.

Word Map on EC 6.3.5.5

6.3.5.5

pyrimidine

dihydroorotase

cpsases

transcarbamoylase

2.1.3.2

ornithine-urea

2.7.2.9

3.5.2.3

acivicin

caspase-activated

dhoase

ureotelic

atcase

lungfish

ammonia-dependent

carab

5-phosphoribosyl

1-pyrophosphate

protopterus

n-acetyl-l-glutamate

drug development

medicine

Reaction

2 ATP +

Synonyms

CAD, CAD carbamoyl-phosphate synthetase, CAD protein, Carbamoyl phosphate synthase (glutamine), carbamoyl phosphate synthetase, Carbamoyl phosphate synthetase (glutamine-hydrolyzing), carbamoyl phosphate synthetase 1, carbamoyl phosphate synthetase II, carbamoyl phosphate synthetase III, carbamoyl-phosphate synthetase, Carbamoyl-phosphate synthetase (glutamine-hydrolysing), carbamoyl-phosphate synthetase 2, Carbamoylphosphate synthase, Carbamoylphosphate synthetase, Carbamoylphosphate synthetase II, Carbamyl phosphate synthetase (glutamine), Carbamyl phosphate sythetase II, carbamylphosphate synthetase - aspartate transcarbamylase, CPA2, CPS, CPS II (glutamine-dependent), CPS III, CPS III (glutamine- and N-acetyl-L-glutamine-dependent), CPS1, CPSase, CPSase type II, CPSase-A, CPSase-P, CPSII, EC 2.7.2.9, Glutamine-dependent carbamyl phosphate synthetase, glutamine-hydrolyzing CPSase, MGG_04503, More, MtCPSs1, MtCPSs2, Synthase, carbamoylphosphate (glutamine), Synthetase, carbamoylphosphate (glutamine-hydrolyzing)

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor

6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)

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Results	in table
66	Activating Compound
87162	AA Sequence
2	Application
1	CAS Registry Number
28	Cloned(Commentary)
22	Cofactor
8	Crystallization (Commentary)
76	Disease/ Diagnostics
3	Expression
9	General Information
2	General Stability
4	IC50 Value
100	Inhibitors
3	Ki Value [mM]
200	KM Value [mM]
14	Localization
21	Metals/Ions
43	Molecular Weight [Da]
56	Natural Substrates/ Products (Substrates)
490	Organism
1	Oxidation Stability
12	Pathway
91	PDB ID
17	pH Optimum
2	pH Range
1	pH Stability
5	Posttranslational Modification
209	Protein Variants
28	Purification (Commentary)
27	Reaction
3	Reaction Type
137	Reference
36	Source Tissue
17	Specific Activity [micromol/min/mg]
2	Storage Stability
219	Substrates and Products (Substrate)
46	Subunits
73	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
3	Temperature Stability [°C]
145	Turnover Number [1/s]

Localization

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Localization on EC 6.3.5.5 - carbamoyl-phosphate synthase (glutamine-hydrolysing)

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coexpression of small GTPase Rheb with CAD leads to increased accumulation of CAD on lysosomes