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4.2.2.21: chondroitin-sulfate-ABC exolyase

This is an abbreviated version!
For detailed information about chondroitin-sulfate-ABC exolyase, go to the full flat file.

Word Map on EC 4.2.2.21

Reaction

[GlcAbeta(1-3)GalNAc(4S)beta(1-4)]3
=
[GlcAbeta(1-3)GalNAc(4S)beta(1-4)]2
 +
2-(acetylamino)-2-deoxy-3-O-alpha-L-threo-hex-4-enopyranuronosyl-4-O-sulfo-beta-D-galactopyranose

Synonyms

BactnABC, cABCII, chABC, Chondroitin Sulfate Lyase ABC, chondroitinase ABC, chondroitinase ABC II, chondroitinase AC, chondroitinase ACII, chondroitinase-ABC, ChS ABC lyase II, EC 4.2.2.4, EC 4.2.99.6, HCLase

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.2 Acting on polysaccharides
                4.2.2.21 chondroitin-sulfate-ABC exolyase

Specific Activity

Specific Activity on EC 4.2.2.21 - chondroitin-sulfate-ABC exolyase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1.45
-
30°C, pH 7.5
1210
substrate chondroitin sulfate C, pH 7.0, 30°C
122.3
-
substrate dermatan sulfate, pH 8.0
1230
substrate chondroitin sulfate A, pH 7.0, 30°C
1350
substrate chondroitin sulfate D, pH 7.0, 30°C
14.8
-
substrate hyaluronan, pH 8.0
1480
substrate chondroitin sulfate E, pH 7.0, 30°C
174.6
-
substrate chondroitin 6-sulfate, pH 8.0
290.6
-
substrate chondroitin 4-sulfate, pH 8.0
34
-
pH 8.0, 37°C
34.8
-
substrate chondroitin sulfate E, pH 8.0
37.5
-
pH 8.0, 37°C
43
-
pH 8.0, 37°C
54.2
-
substrate chondroitin sulfate D, pH 8.0
69.8
-
substrate chondroitin, pH 8.0
750
substrate dermatan sulfate, pH 7.0, 30°C
800
substrate hyaluronan, pH 7.0, 30°C
additional information