Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | - |
Pedobacter heparinus | |
Fe2+ | - |
Pedobacter heparinus | |
heparin | - |
Pedobacter heparinus | |
heparitin sulfate | - |
Pedobacter heparinus | |
keratosulfate | - |
Pedobacter heparinus | |
Zn2+ | - |
Pedobacter heparinus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Pedobacter heparinus | |
Mg2+ | - |
Pedobacter heparinus | |
Mn2+ | - |
Pedobacter heparinus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
150000 | - |
or slightly lower, gel filtration | Proteus vulgaris |
150000 | - |
or slightly lower, gel filtration | Pedobacter heparinus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pedobacter heparinus | - |
- |
- |
Proteus vulgaris | - |
growth on medium containing chondroitin sulfate C | - |
Proteus vulgaris NCTC 4636 | - |
growth on medium containing chondroitin sulfate C | - |
Purification (Comment) | Organism |
---|---|
- |
Proteus vulgaris |
- |
Pedobacter heparinus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
37.5 | - |
pH 8.0, 37°C | Proteus vulgaris |
43 | - |
pH 8.0, 37°C | Pedobacter heparinus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
chondroitin | - |
Pedobacter heparinus | ? | - |
? | |
chondroitin | reaction is less efficient than for chondroitin sulfates | Proteus vulgaris | ? | - |
? | |
chondroitin sulfate A | - |
Proteus vulgaris | DELTA4,5-unsaturated chondroitin sulfate A disaccharide | - |
? | |
chondroitin sulfate A | - |
Pedobacter heparinus | DELTA4,5-unsaturated chondroitin sulfate A disaccharide | - |
? | |
chondroitin sulfate B | - |
Proteus vulgaris | DELTA4,5-unsaturated chondroitin sulfate B disaccharide | - |
? | |
chondroitin sulfate C | - |
Proteus vulgaris | DELTA4,5-unsaturated chondroitin sulfate C disaccharide | - |
? | |
chondroitin sulfate C | - |
Pedobacter heparinus | DELTA4,5-unsaturated chondroitin sulfate C disaccharide | - |
? | |
hyaluronic acid | - |
Pedobacter heparinus | ? | - |
? | |
hyaluronic acid | bad substrate | Proteus vulgaris | ? | - |
? | |
additional information | no substrate: chondroitin sulfate B, keratosulfate, heparin, or heparitin sulfate | Pedobacter heparinus | ? | - |
? | |
additional information | no substrate: keratosulfate, heparin, or heparitin sulfate | Proteus vulgaris | ? | - |
? | |
additional information | no substrate: keratosulfate, heparin, or heparitin sulfate | Proteus vulgaris NCTC 4636 | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 150000 or slightly lower, SDS-PAGE | Proteus vulgaris |
monomer | 1 * 150000 or slightly lower, SDS-PAGE | Pedobacter heparinus |
Synonyms | Comment | Organism |
---|---|---|
chondroitinase ABC | - |
Proteus vulgaris |
chondroitinase AC | - |
Pedobacter heparinus |
chondroitinase-ABC | - |
Proteus vulgaris |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Proteus vulgaris |
37 | - |
- |
Pedobacter heparinus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | - |
substrate hyaluronic acid | Pedobacter heparinus |
6 | - |
substrate chondroitin | Pedobacter heparinus |
6.2 | - |
substrate chondroitin | Proteus vulgaris |
6.6 | - |
substrate chondroitin sulfate A, or C | Pedobacter heparinus |
6.8 | - |
substrate hyaluronic acid | Proteus vulgaris |
8 | - |
substrate chondroitin sulfate A, B or C | Proteus vulgaris |