3.5.4.4: adenosine deaminase

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For detailed information about adenosine deaminase, go to the full flat file.

Word Map on EC 3.5.4.4

3.5.4.4

purine

nucleoside

lymphocyte

immunodeficiency

inosine

pleural

tuberculous

deamination

effusion

erythrocyte

phosphorylase

agonist

leukemia

5'-nucleotidase

deoxyadenosine

marrow

xanthine

adenylate

hypoxanthine

t-cells

lymphoid

ehna

dipyridamole

purinergic

hematopoietic

exudative

lipolysis

pleurisy

meningitis

theophylline

datp

ecto-5\'-nucleotidase

s-adenosylhomocysteine

2-chloroadenosine

dpcpx

autoinflammatory

pericarditis

acid-fast

deoxycytidine

transudate

antilipolytic

diphosphohydrolase

hypoxanthine-guanine

adenosine-induced

ectonucleotidases

n6-cyclopentyladenosine

empyema

deaminases

ntpdases

purinoceptors

medicine

pharmacology

drug development

diagnostics

analysis

Reaction

Synonyms

AD, ADA, ADA1, ADA2, ADAI, ADAII, ADAIII, Adenosine aminohydrolase, adenosine deaminase, adenosine deaminase 1, adenosine deaminase 2, ciADA, HadA, LADA, MadA, MJ1541, PvADA, SADA, SCO4901, TadA

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.4 In cyclic amidines

3.5.4.4 adenosine deaminase

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Results	in table
14	Activating Compound
16116	AA Sequence
26	Application
1	CAS Registry Number
13	Cloned(Commentary)
11	Crystallization (Commentary)
10109	Disease/ Diagnostics
9	Expression
23	General Information
4	General Stability
1	IC50 Value
359	Inhibitors
38	kcat/KM [mM/s]
140	Ki Value [mM]
117	KM Value [mM]
23	Localization
25	Metals/Ions
55	Molecular Weight [Da]
69	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
338	Organism
10	Pathway
86	PDB ID
49	pH Optimum
11	pH Range
4	pH Stability
1	pI Value
1	Posttranslational Modification
21	Protein Variants
50	Purification (Commentary)
4	Reaction
2	Reaction Type
166	Reference
172	Source Tissue
115	Specific Activity [micromol/min/mg]
20	Storage Stability
285	Substrates and Products (Substrate)
26	Subunits
141	Synonyms
1	Systematic Name
27	Temperature Optimum [°C]
4	Temperature Range [°C]
15	Temperature Stability [°C]
42	Turnover Number [1/s]

General Stability

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General Stability on EC 3.5.4.4 - adenosine deaminase

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30% activity loss after heating for 1 h at 60°C and neutral pH

Kitasatospora aureofaciens

209613

50% activity loss after frequent freezing and thawing

Aspergillus terricola

209631

conversion of smaller enzyme to intermediate and larger enzyme possible

Homo sapiens

209610

Mg2+ or Mn2+ required during purification procedure, addition of serum albumin protects against loss of activity by freezing

Micrococcus sodonensis

209609