3.5.4.4: adenosine deaminase
This is an abbreviated version!
For detailed information about adenosine deaminase, go to the full flat file.
Word Map on EC 3.5.4.4
-
3.5.4.4
-
purine
-
nucleoside
-
lymphocyte
-
immunodeficiency
-
inosine
-
pleural
-
tuberculous
-
deamination
-
effusion
-
erythrocyte
-
phosphorylase
-
agonist
-
leukemia
-
5'-nucleotidase
-
deoxyadenosine
-
marrow
-
xanthine
-
adenylate
-
hypoxanthine
-
t-cells
-
lymphoid
-
ehna
-
dipyridamole
-
purinergic
-
hematopoietic
-
exudative
-
lipolysis
-
pleurisy
-
meningitis
-
theophylline
-
datp
-
ecto-5\'-nucleotidase
-
s-adenosylhomocysteine
-
2-chloroadenosine
-
dpcpx
-
autoinflammatory
-
pericarditis
-
acid-fast
-
deoxycytidine
-
transudate
-
antilipolytic
-
diphosphohydrolase
-
hypoxanthine-guanine
-
adenosine-induced
-
ectonucleotidases
-
n6-cyclopentyladenosine
-
empyema
-
deaminases
-
ntpdases
-
purinoceptors
-
medicine
-
pharmacology
-
drug development
-
diagnostics
-
analysis
- 3.5.4.4
- purine
- nucleoside
- lymphocyte
- immunodeficiency
- inosine
- pleural
-
tuberculous
-
deamination
- effusion
- erythrocyte
- phosphorylase
- agonist
- leukemia
- 5'-nucleotidase
- deoxyadenosine
- marrow
- xanthine
- adenylate
- hypoxanthine
- t-cells
-
lymphoid
- ehna
- dipyridamole
-
purinergic
-
hematopoietic
-
exudative
-
lipolysis
- pleurisy
- meningitis
- theophylline
- datp
-
ecto-5\'-nucleotidase
- s-adenosylhomocysteine
- 2-chloroadenosine
- dpcpx
-
autoinflammatory
- pericarditis
-
acid-fast
- deoxycytidine
-
transudate
-
antilipolytic
-
diphosphohydrolase
-
hypoxanthine-guanine
-
adenosine-induced
- ectonucleotidases
-
n6-cyclopentyladenosine
- empyema
- deaminases
- ntpdases
-
purinoceptors
- medicine
- pharmacology
- drug development
- diagnostics
- analysis
Reaction
Synonyms
AD, ADA, ADA1, ADA2, ADAI, ADAII, ADAIII, Adenosine aminohydrolase, adenosine deaminase, adenosine deaminase 1, adenosine deaminase 2, ciADA, HadA, LADA, MadA, MJ1541, PvADA, SADA, SCO4901, TadA
ECTree
3.5.4.4 adenosine deaminaseAdvanced search results
results (
results (KM Value
KM Value on EC 3.5.4.4 - adenosine deaminase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.0044
5'-methylthioadenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.0087
5'-methylthioadenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.0095
5'-methylthioadenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.022
5'-methylthioadenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.0306
5'-methylthioadenosine
pH 8.0, temperature not specified in the publication, wild-type enzyme
0.04461
5'-methylthioadenosine
pH 8.0, temperature not specified in the publication, mutant enzyme C27Q/L227I
0.05256
5'-methylthioadenosine
pH 8.0, temperature not specified in the publication, mutant enzyme L179H
0.115
5'-methylthioadenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.20034
5'-methylthioadenosine
pH 8.0, temperature not specified in the publication, mutant enzyme T174A
0.22422
5'-methylthioadenosine
pH 8.0, temperature not specified in the publication, mutant enzyme D176A/L179A
0.25326
5'-methylthioadenosine
pH 8.0, temperature not specified in the publication, mutant enzyme D176M
0.26747
5'-methylthioadenosine
pH 8.0, temperature not specified in the publication, mutant enzyme T174I
0.28928
5'-methylthioadenosine
pH 8.0, temperature not specified in the publication, mutant enzyme D176A
0.37605
5'-methylthioadenosine
pH 8.0, temperature not specified in the publication, mutant enzyme F136L
0.00943
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme T174I
0.01728
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme, wild-type enzyme (refolded)
0.01784
adenosine
pH 8.0, temperature not specified in the publication, wild-type enzyme
0.02064
adenosine
pH 8.0, temperature not specified in the publication, wild-type enzyme
0.02113
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme L179H
0.02344
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme C27Q/L227I
0.026
adenosine
-
25°C, 50 mM Tris-HCl buffer, pH 7.4, enzyme concentration 1.5 nM
0.032
adenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.03874
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme M155A
0.04203
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme T174A
0.05641
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme M155A (refolded)
0.057
adenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.06
adenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.072
adenosine
pH and temperature not specified in the publication, mutant enzyme Y136R
0.083
adenosine
-
mutant enzyme D172E, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.087
adenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.088
adenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.104
adenosine
-
mutant enzyme D172A, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.12
adenosine
-
wild type enzyme, in 100 mM Tris-HCl buffer (pH 8.0), temperature not specified in the publication
0.12628
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme D176A
0.15
adenosine
pH and temperature not specified in the publication, wild-type enzyme
0.15
adenosine
pH and temperature not specified in the publication, mutant enzyme E150R
0.15897
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme D176A/L179A
0.29961
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme D176M
0.32206
adenosine
pH 8.0, temperature not specified in the publication, mutant enzyme F136L
additional information
additional information
thermodynamics and kinetics
-
additional information
additional information
-
isozymes ADA1 and ADA2 are kinetically distinct
-
additional information
additional information
-
kinetics of the large and the small isozyme
-
additional information
additional information
-
kinetics of the large and the small isozyme
-
additional information
additional information
-
optimization of a spectrometric kinetic measurement method pure enzyme, kinetics in presence of substrate, product and inhibitor, overview
-
additional information
additional information
-
optimization of a spectrometric kinetic measurement method using Hut78 cell extract, kinetics in presence of substrate, product and inhibitor, overview
-
