Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 3.5.4.4 - adenosine deaminase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sim, M.K.; Maguire, M.H.
Studies on adenosine deaminase. 1. Purification and some properties of bovine placental adenosine deaminase
Eur. J. Biochem.
23
17-21
1971
Bos taurus
Manually annotated by BRENDA team
Akedo, H.; Nishihara, H.; Shinkai, K.; Komatsu, K.; Ishikawa, S.
Multiple forms of human adenosine deaminase. 1. Purification and characterization of two molecular species
Biochim. Biophys. Acta
276
257-271
1972
Homo sapiens
Manually annotated by BRENDA team
Harbison, G.R.; Fisher, J.R.
Purification, properties and temperatur dependence of the adenosine deaminase from a poikilotherm (Bay scallop)
Arch. Biochem. Biophys.
154
81-95
1973
Argopecten irradians concentricus
-
Manually annotated by BRENDA team
Osborne, W.R.A.; Spencer, N.
Partial purification and properties of the common inherited forms of adenosine deaminase from human erythrocytes
Biochem. J.
133
117-123
1973
Homo sapiens
Manually annotated by BRENDA team
Rossi, C.A.; Lucacchini, A.
Purification and some properties of calf thymus adenosine deaminase
Biochem. Soc. Trans.
2
1313-1315
1974
Bos taurus
-
Manually annotated by BRENDA team
Pickard, M.A.
Purification and some properties of the soluble and membrane-bound adenosine deaminases of Micrococcus sodonensis ATCC 11880 and their distribution within the family Micrococcaceae
Can. J. Biochem.
53
344-353
1975
Micrococcus candidus, Macrococcus caseolyticus, Micrococcus freudenreichii, Micrococcus luteus, Staphylococcus aureus, Kocuria rosea, Micrococcus sodonensis, Micrococcus sp., Staphylococcus aerogenes
Manually annotated by BRENDA team
Van der Weyden, M.B.; Kelley, W.N.
Human adenosine deaminase, Distributions and properties
J. Biol. Chem.
251
5448-5456
1976
Homo sapiens
Manually annotated by BRENDA team
Sakai, T.; Jun, H.K.
Purification and crystallization of adenosine deaminase in Pseudomonas iodinum IFO 3558
FEBS Lett.
86
174-178
1978
Pseudomonas iodinum
Manually annotated by BRENDA team
Crabbe, M.J.; Kavanagh, J.P.
The purification and preliminary investigation of fumarase, peroxidase, diamine oxidase and adenosine deaminase from human seminal plasma
Biochem. Soc. Trans.
5
735-737
1977
Homo sapiens
Manually annotated by BRENDA team
Rosinova, M.; Zelinkova, E.; Zelinka, J.
Adenosine aminohydrolase from Streptomyces aureofaciens
Collect. Czech. Chem. Commun.
43
2324-2329
1978
Kitasatospora aureofaciens
-
Manually annotated by BRENDA team
Agarwal, R.P.; Parks, R.E.
Adenosine deaminase from human erythrocytes
Methods Enzymol.
67
502-507
1978
Bos taurus, Homo sapiens
-
Manually annotated by BRENDA team
Philips, A.V.; Robbins, D.J.; Coleman, M.S.
Immunoaffinity purification and fluorescence studies of human adenosine deaminase
Biochemistry
26
2893-2903
1987
Homo sapiens
Manually annotated by BRENDA team
Gabellieri, E.; Bernini, S.; Piras, L.; Cioni, P.; Balestreri, E.; Cercignani, G.; Felicioli, R.
Purification, stability and kinetic properties of highly purified adenosine deaminase from Bacillus cereus NCIB 8122
Biochim. Biophys. Acta
884
490-496
1986
Bacillus cereus
Manually annotated by BRENDA team
Daddona, P.E.; Wiesmann, W.P.; Lambros, C.; Kelley, W.N.; Webster, H.K.
Human malaria parasite adenosine deaminase
J. Biol. Chem.
259
1472-1475
1984
Homo sapiens, Plasmodium falciparum
Manually annotated by BRENDA team
Jaroszewicz, L.; Wyszynska, M.
Adenosine deaminase from pig thyroid gland. Purification and some properties
Biochem. Biophys. Res. Commun.
109
138-145
1982
Sus scrofa
Manually annotated by BRENDA team
Hunt, S.W.3rd.; Hoffee, P.A.
Adenosine deaminase from deoxycoformycin-sensitive and -resistent rat hepatoma cells
J. Biol. Chem.
257
14239-14244
1982
Rattus norvegicus
Manually annotated by BRENDA team
Lewis, A.S.; McCalla, C.; Murphy, L.
A simple conventional method for the purification of bovine spleen adenosine deaminase in high yield: Physical properties
J. Appl. Biochem.
3
378-386
1981
Bos taurus
-
Manually annotated by BRENDA team
Daddona, P.E.
Human adenosine deaminase: Properties and turnover in cultured T and B lymphoblasts
J. Biol. Chem.
256
12496-12501
1981
Homo sapiens
Manually annotated by BRENDA team
Wiginton, D.A.; Coleman, M.S.; Hutton, J.J.
Purification, characterization and radioimmunoassay of adenosine deaminase from human leukaemic granulocytes
Biochem. J.
195
389-397
1981
Homo sapiens
Manually annotated by BRENDA team
Tsukada, T.; Yoshino, M.
Adenosine deaminase from Azotobacter vinelandii. Purification and properties
Arch. Microbiol.
128
228-232
1980
Azotobacter vinelandii, Azotobacter vinelandii 0
Manually annotated by BRENDA team
Nygaard, P.
Adenosine deaminase from Escherichia coli
Methods Enzymol.
51
508-512
1978
Escherichia coli
Manually annotated by BRENDA team
Centelles, J.J.; Franco, R.
Slight differences between adenosine deaminase from different species. An immunochemical study
Arch. Int. Physiol. Biochim.
98
421-431
1990
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Schrader, W.P.; West, C.A.; Miczek, A.D.; Norton, E.K.
Characterization of the adenosine deaminase-adenosine deaminase complexing protein binding reaction
J. Biol. Chem.
265
19312-19318
1990
Cavia porcellus, Oryctolagus cuniculus, Homo sapiens, Platyrrhini, Mus musculus
Manually annotated by BRENDA team
Jun, H.K.; Kim, T.S.; Sakai, T.
Purification and characterization of extracellular adenosine deaminase from a Streptomyces sp.
J. Ferment. Bioeng.
71
6-11
1991
Streptomyces sp., Streptomyces sp. J-845S
-
Manually annotated by BRENDA team
Ling, F.; Inoue, Y.; Kimura, A.
Purification and characterization of adenosine deaminase from Klebsiella sp. LF 1202
J. Ferment. Bioeng.
71
89-92
1991
Klebsiella sp., Klebsiella sp. LF 1202
-
Manually annotated by BRENDA team
Hough, R.F.; Bass, B.L.
Purification of the Xenopus laevis double-stranded RNA adenosine deaminase
J. Biol. Chem.
269
9933-9939
1994
Xenopus laevis
Manually annotated by BRENDA team
Jun, H.K.; Yeeh, Y.
Purification and charaterization of an extracellular adenosine deaminase from Nocardioides sp. J-326TK
Biotechnol. Appl. Biochem.
20
265-277
1994
Nocardioides sp., Nocardioides sp. J-326TK
Manually annotated by BRENDA team
Abu-Shady, M.R.; Elshafei, A.M.; El-Beih, F.M.; Mohamed, L.A.
Properties of adenosine deaminase in extracts of Aspergillus terricola
Acta Microbiol. Pol.
43
305-311
1994
Aspergillus terricola
Manually annotated by BRENDA team
Lupidi, G.; Marmocchi, F.; Cristalli, G.
Inhibition studies on membrane adenosine deaminase from human placenta
Biochem. Mol. Biol. Int.
46
1071-1080
1998
Homo sapiens
Manually annotated by BRENDA team
Kinoshita, T.; Nishio, N.; Sato, A.; Murata, M.
Crystallization and preliminary analysis of bovine adenosine deaminase
Acta Crystallogr. Sect. D
55
2031-2032
1999
Bos taurus
Manually annotated by BRENDA team
Challa, A.; Johnson, S.; Robertson, K.; Gunasekaran, M.
Properties of adenosine deaminase from Candida albicans
J. Basic Microbiol.
39
97-101
1999
Candida albicans
Manually annotated by BRENDA team
Singh, L.S.; Sharma, R.
Purification and characterization of intestinal adenosine deaminase from mice
Mol. Cell. Biochem.
204
127-134
2000
Mus musculus
Manually annotated by BRENDA team
Kinoshita, T.; Nishio, N.; Nakanishi, I.; Sato, A.; Fujii, T.
Structure of bovine adenosine deaminase complexed with 6-hydroxy-1,6-dihydropurine riboside
Acta Crystallogr. Sect. D
59
299-303
2003
Bos taurus
Manually annotated by BRENDA team
Mardanyan, S.S.; Sharoyan, S.G.; Antonyan, A.A.; Lupidi, G.; Cristalli, G.
Interaction of adenosine deaminase with inhibitors. Chemical modification by diethyl pyrocarbonate
Biochemistry (Moscow)
67
770-777
2002
Bos taurus
Manually annotated by BRENDA team
Ben-Shooshan, I.; Kessel, A.; Ben-Tal, N.; Cohen-Luria, R.; Parola, A.H.
On the regulatory role of dipeptidyl peptidase IV (:CD26:adenosine deaminase complexing protein) on adenosine deaminase activity
Biochim. Biophys. Acta
1587
21-30
2002
Bos taurus
Manually annotated by BRENDA team
Iwaki-Egawa, S.; Watanabe, Y.
Characterization and purification of adenosine deaminase 1 from human and chicken liver
Comp. Biochem. Physiol. B
133
173-182
2002
Gallus gallus, Homo sapiens
Manually annotated by BRENDA team
Iwaki-Egawa, S.; Namiki, C.; Watanabe, Y.
Adenosine deaminase 2 from chicken liver: purification, characterization, and N-terminal amino acid sequence
Comp. Biochem. Physiol. B
137
247-254
2004
Gallus gallus
Manually annotated by BRENDA team
Alrokayan, S.
Purification and characterization of adenosine deaminase from camel skeletal muscle
Int. J. Biochem. Cell Biol.
34
1608-1618
2002
Camelus dromedarius
Manually annotated by BRENDA team
Castro, C.; Britt, B.M.
Binding thermodynamics of the transition state analogue coformycin and of the ground state analogue 1-deazaadenosine to bovine adenosine deaminase
J. Enzyme Inhib.
16
217-232
2001
Bos taurus
Manually annotated by BRENDA team
Ataie, G.; Safarian, S.; Divsalar, A.; Saboury, A.A.; Moosavi-Movahedi, A.A.; Ranjbar, B.; Cristalli, G.; Mardanian, S.
Kinetic and structural analysis of the inhibition of adenosine deaminase by acetaminophen
J. Enzyme Inhib. Med. Chem.
19
71-78
2004
Bos taurus
Manually annotated by BRENDA team
Reayi, A.; Hosmane, R.S.
Inhibition of adenosine deaminase by novel 5:7 fused heterocycles containing the imidazo[4,5-e][1,2,4]triazepine ring system: a structure-activity relationship study
J. Med. Chem.
47
1044-1050
2004
Bos taurus
Manually annotated by BRENDA team
Sharoyan, S.; Antonyan, A.; Mardanyan, S.; Lupidi, G.; Cristalli, G.
Influence of dipeptidyl peptidase IV on enzymatic properties of adenosine deaminase
Acta Biochim. Pol.
53
539-546
2006
Bos taurus, Homo sapiens
Manually annotated by BRENDA team
Adachi, H.; Takano, K.; Niino, A.; Matsumura, H.; Kinoshita, T.; Warizaya, M.; Inoue, T.; Mori, Y.; Sasaki, T.
Solution stirring initiates nucleation and improves the quality of adenosine deaminase crystals
Acta Crystallogr. Sect. D
D61
759-762
2005
Bos taurus
Manually annotated by BRENDA team
Tuluce, Y.; Celik, I.
Effects of indole-3-acetic acid and kinetin on the adenosine deaminase activity in various tissues of rats
Asian J. Chem.
18
528-532
2005
Rattus norvegicus
-
Manually annotated by BRENDA team
Zavialov, A.V.; Engstroem, A.
Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity
Biochem. J.
391
51-57
2005
Homo sapiens (Q9NZK5), Homo sapiens
Manually annotated by BRENDA team
Iwaki-Egawa, S.; Yamamoto, T.; Watanabe, Y.
Human plasma adenosine deaminase 2 is secreted by activated monocytes
Biol. Chem.
387
319-321
2006
Homo sapiens
Manually annotated by BRENDA team
Vale, M.R.; Pereira, R.V.; Almeida, S.M.; Almeida, Y.M.; Nunes, S.F.
Characterization of adenosine deaminase (ADA) in hemolymph of Biomphalaria glabrata
Braz. J. Biol.
65
371-376
2005
Biomphalaria glabrata
Manually annotated by BRENDA team
Kashyap, R.S.; Kainthla, R.P.; Mudaliar, A.V.; Purohit, H.J.; Taori, G.M.; Daginawala, H.F.
Cerebrospinal fluid adenosine deaminase activity: a complimentary tool in the early diagnosis of tuberculous meningitis
Cerebrospinal Fluid Res.
3
5
2006
Homo sapiens
Manually annotated by BRENDA team
Aghaei, M.; Karami-Tehrani, F.; Salami, S.; Atri, M.
Adenosine deaminase activity in the serum and malignant tumors of breast cancer: the assessment of isoenzyme ADA1 and ADA2 activities
Clin. Biochem.
38
887-891
2005
Homo sapiens
Manually annotated by BRENDA team
Hitoglou, S.; Zournatzi, V.; Gougoustamou, D.; Hatzistilianou, M.; Tzafettas, J.
Adenosine deaminase activity and its isoenzyme pattern in women with recurrent spontaneous abortions
Gynecol. Obstet. Invest.
58
126-129
2004
Homo sapiens
Manually annotated by BRENDA team
Kozat, S.; Ekin, S.; Kaya, A.; Denizhan, V.
Serum adenosine deaminase activity and biochemical parameters in chronic fascioliasis in sheep
Indian Vet. J.
83
349-350
2006
Ovis aries
-
Manually annotated by BRENDA team
Paul, M.K.; Grover, V.; Mukhopadhyay, A.K.
Merits of HPLC-based method over spectrophotometric method for assessing the kinetics and inhibition of mammalian adenosine deaminase
J. Chromatogr. B
822
146-153
2005
Bos taurus, Homo sapiens
Manually annotated by BRENDA team
Terasaka, T.; Kinoshita, T.; Kuno, M.; Seki, N.; Tanaka, K.; Nakanishi, I.
Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors
J. Med. Chem.
47
3730-3743
2004
Bos taurus (P56658)
Manually annotated by BRENDA team
Da Settimo, F.; Primofiore, G.; La Motta, C.; Taliani, S.; Simorini, F.; Marini, A.M.; Mugnaini, L.; Lavecchia, A.; Novellino, E.; Tuscano, D.; Martini, C.
Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies
J. Med. Chem.
48
5162-5174
2005
Bos taurus
Manually annotated by BRENDA team
Shu, Q.; Frieden, C.
Relation of enzyme activity to local/global stability of murine adenosine deaminase: 19F NMR studies
J. Mol. Biol.
345
599-610
2005
Mus musculus (P03958), Mus musculus
Manually annotated by BRENDA team
Vivekanandhan, S.; Soundararajan, C.C.; Tripathi, M.; Maheshwari, M.C.
Adenosine deaminase and 5'-nucleotidase activities in peripheral blood T cells of multiple sclerosis patients
Neurochem. Res.
30
453-456
2005
Homo sapiens
Manually annotated by BRENDA team
Okur, E.; Inanc, F.; Yildirim, I.; Kilinc, M.; Kilic, M.A.
Malondialdehyde level and adenosine deaminase activity in nasal polyps
Otolaryngol. Head Neck Surg.
134
37-40
2006
Homo sapiens
Manually annotated by BRENDA team
Yilmaz, H.R.; Sogut, S.; Ozyurt, B.; Ozugurlu, F.; Sahin, S.; Isik, B.; Uz, E.; Ozyurt, H.
The activities of liver adenosine deaminase, xanthine oxidase, catalase, superoxide dismutase enzymes and the levels of malondialdehyde and nitric oxide after cisplatin toxicity in rats: protective effect of caffeic acid phenethyl ester
Toxicol. Ind. Health
21
67-73
2005
Rattus norvegicus
Manually annotated by BRENDA team
Wu, J.Z.; Yeh, L.T.; Lin, C.C.; Hong, Z.
Conversion of viramidine to ribavirin in vivo by adenosine deaminase and its inhibition by 2-deoxycoformycin
Antiviral Chem. Chemother.
17
33-39
2006
Rattus norvegicus
Manually annotated by BRENDA team
Kuno, M.; Seki, N.; Tsujimoto, S.; Nakanishi, I.; Kinoshita, T.; Nakamura, K.; Terasaka, T.; Nishio, N.; Sato, A.; Fujii, T.
Anti-inflammatory activity of non-nucleoside adenosine deaminase inhibitor FR234938
Eur. J. Pharmacol.
534
241-249
2006
Homo sapiens
Manually annotated by BRENDA team
Mohamed, T.M.
Adenosine deaminase from camel tick Hyalomma dromedarii: purification and characterization
Exp. Appl. Acarol.
40
101-111
2006
Hyalomma dromedarii
Manually annotated by BRENDA team
Ali, E.M.
Fasciola gigantica: purification and characterization of adenosine deaminase
Exp. Parasitol.
119
285-290
2008
Fasciola gigantica
Manually annotated by BRENDA team
Sadat Hayatshahi, S.H.; Abdolmaleki, P.; Ghiasi, M.; Safarian, S.
QSARs and activity predicting models for competitive inhibitors of adenosine deaminase
FEBS Lett.
581
506-514
2007
Homo sapiens
Manually annotated by BRENDA team
Tyler, P.C.; Taylor, E.A.; Froehlich, R.F.; Schramm, V.L.
Synthesis of 5-methylthio coformycins: specific inhibitors for malarial adenosine deaminase
J. Am. Chem. Soc.
129
6872-6879
2007
Bos taurus, Homo sapiens, Plasmodium falciparum
Manually annotated by BRENDA team
Ajloo, D.; Saboury, A.A.; Haghi-Asli, N.; Ataei-Jafarai, G.; Moosavi-Movahedi, A.A.; Ahmadi, M.; Mahnam, K.; Namaki, S.
Kinetic, thermodynamic and statistical studies on the inhibition of adenosine deaminase by aspirin and diclofenac
J. Enzyme Inhib. Med. Chem.
22
395-406
2007
Bos taurus
Manually annotated by BRENDA team
Alunni, S.; Orru, M.; Ottavi, L.
A study on the inhibition of adenosine deaminase
J. Enzyme Inhib. Med. Chem.
23
182-189
2008
Bos taurus
Manually annotated by BRENDA team
Van De Wiele, C.J.; Joachims, M.L.; Fesler, A.M.; Vaughn, J.G.; Blackburn, M.R.; McGee, S.T.; Thompson, L.F.
Further differentiation of murine double-positive thymocytes is inhibited in adenosine deaminase-deficient murine fetal thymic organ culture
J. Immunol.
176
5925-5933
2006
Mus musculus, Mus musculus C57BL/6
Manually annotated by BRENDA team
Ujjinamatada, R.K.; Phatak, P.; Burger, A.M.; Hosmane, R.S.
Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common heterocyclic base, 4(7)-amino-6(5)H-imidazo[4,5-d]pyridazin-7(4)one
J. Med. Chem.
51
694-698
2008
Bos taurus
Manually annotated by BRENDA team
Antonioli, L.; Fornai, M.; Colucci, R.; Ghisu, N.; Da Settimo, F.; Natale, G.; Kastsiuchenka, O.; Duranti, E.; Virdis, A.; Vassalle, C.; La Motta, C.; Mugnaini, L.; Breschi, M.C.; Blandizzi, C.; Del Taca, M.
Inhibition of adenosine deaminase attenuates inflammation in experimental colitis
J. Pharmacol. Exp. Ther.
322
435-442
2007
Rattus norvegicus
Manually annotated by BRENDA team
Kemeny-Beke, A.; Jakab, A.; Zsuga, J.; Vecsernyes, M.; Karsai, D.; Pasztor, F.; Grenczer, M.; Szentmiklosi, A.J.; Berta, A.; Gesztelyi, R.
Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium
Pharmacol. Res.
56
124-131
2007
Cavia porcellus
Manually annotated by BRENDA team
Kowalczyk, E.; Kopff, M.; Kowalski, J.; Kopff, A.; Mikhailidis, D.P.; Barylski, M.; Banach, M.
Effect of cardiovascular drugs on adenosine deaminase activity
Angiology
59
740-744
2008
Oryctolagus cuniculus
Manually annotated by BRENDA team
Belle, L.P.; De Bona, K.S.; Abdalla, F.H.; Pimentel, V.C.; Pigatto, A.S.; Moretto, M.B.
Comparative evaluation of adenosine deaminase activity in cerebral cortex and hippocampus of young and adult rats: effect of garlic extract (Allium sativum L.) on their susceptibility to heavy metal exposure
Basic Clin. Pharmacol. Toxicol.
104
408-413
2009
Rattus norvegicus
Manually annotated by BRENDA team
Kinoshita, T.; Tada, T.; Nakanishi, I.
Conformational change of adenosine deaminase during ligand-exchange in a crystal
Biochem. Biophys. Res. Commun.
373
53-57
2008
Bos taurus (P56658)
Manually annotated by BRENDA team
Sharoyan, S.G.; Antonyan, A.A.; Mardanyan, S.S.; Lupidi, G.; Cuccioloni, M.; Angeletti, M.; Cristalli, G.
Complex of dipeptidyl peptidase II with adenosine deaminase
Biochemistry (Moscow)
73
943-949
2008
Bos taurus
Manually annotated by BRENDA team
Vistoli, G.; Pedretti, A.; Alessandrini, L.; Casati, S.; Ciuffreda, P.; Meroni, G.; Santaniello, E.
Enhanced activity or resistance of adenosine derivatives towards adenosine deaminase-catalyzed deamination: Influence of ribose modifications
Bioorg. Med. Chem. Lett.
19
2877-2879
2009
Bos taurus (P56658)
Manually annotated by BRENDA team
Pospisilova, H.; Sebela, M.; Novak, O.; Frebort, I.
Hydrolytic cleavage of N6-substituted adenine derivatives by eukaryotic adenine and adenosine deaminases
Biosci. Rep.
28
335-347
2008
Arabidopsis thaliana (Q8LPL7), Arabidopsis thaliana, Saccharomyces cerevisiae (P53909), Saccharomyces cerevisiae, Schizosaccharomyces pombe (Q9P6I7), Schizosaccharomyces pombe
Manually annotated by BRENDA team
Poursharifi, P.; Saghiri, R.; Ebrahimi-Rad, M.; Nazem, H.; Pourpak, Z.; Moin, M.; Shams, S.
Adenosine deaminase in patients with primary immunodeficiency syndromes: The analysis of serum ADA1 and ADA2 activities
Clin. Biochem.
42
1438-1443
2008
Homo sapiens
Manually annotated by BRENDA team
Rosemberg, D.B.; Rico, E.P.; Senger, M.R.; Dias, R.D.; Bogo, M.R.; Bonan, C.D.; Souza, D.O.
Kinetic characterization of adenosine deaminase activity in zebrafish (Danio rerio) brain
Comp. Biochem. Physiol. B
151
96-101
2008
Danio rerio
Manually annotated by BRENDA team
Kisacik, B.; Akdogan, A.; Yilmaz, G.; Karadag, O.; Yilmaz, F.M.; Koklu, S.; Yuksel, O.; Ertenli, A.I.; Kiraz, S.
Serum adenosine deaminase activities during acute attacks and attack-free periods of familial Mediterranean fever
Eur. J. Intern. Med.
20
44-47
2009
Homo sapiens
Manually annotated by BRENDA team
Medici, R.; Lewkowicz, E.S.; Iribarren, A.M.
Arthrobacter oxydans as a biocatalyst for purine deamination
FEMS Microbiol. Lett.
289
20-26
2008
Pseudarthrobacter oxydans
Manually annotated by BRENDA team
Ajloo, D.; Taghizadeh, E.; Saboury, A.A.; Bazyari, E.; Mahnam, K.
Effects of surfactant, salt and solvent on the structure and activity of adenosine deaminase: molecular dynamic and spectrophotometric studies
Int. J. Biol. Macromol.
43
151-158
2008
Bos taurus (P56658)
Manually annotated by BRENDA team
Pence, S.; Erkutlu, I.; Kurtul, N.; Alptekin, M.; Tan, U.
Effects of progesterone on total brain tissue adenosine deaminase activity in experimental epilepsy
Int. J. Neurosci.
119
204-213
2009
Mus musculus
Manually annotated by BRENDA team
Sibani, S.; Rampakakis, E.; Di Paola, D.; Zannis-Hadjopoulos, M.
Fine mapping and functional activity of the adenosine deaminase origin in murine embryonic fibroblasts
J. Cell. Biochem.
104
773-784
2008
Mus musculus
Manually annotated by BRENDA team
Kosugi, T.; Nakanishi, I.; Kitaura, K.
Binding free energy calculations of adenosine deaminase inhibitor and the effect of methyl substitution in inhibitors
J. Chem. Inf. Model.
49
615-622
2009
Mus musculus (P03958)
Manually annotated by BRENDA team
La Motta, C.; Sartini, S.; Mugnaini, L.; Salerno, S.; Simorini, F.; Taliani, S.; Marini, A.M.; Da Settimo, F.; Lavecchia, A.; Novellino, E.; Antonioli, L.; Fornai, M.; Blandizzi, C.; Del Tacca, M.
Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors
J. Med. Chem.
52
1681-1692
2009
Bos taurus (P56658), Bos taurus
Manually annotated by BRENDA team
Larson, E.T.; Deng, W.; Krumm, B.E.; Napuli, A.; Mueller, N.; Van Voorhis, W.C.; Buckner, F.S.; Fan, E.; Lauricella, A.; DeTitta, G.; Luft, J.; Zucker, F.; Hol, W.G.; Verlinde, C.L.; Merritt, E.A.
Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity
J. Mol. Biol.
381
975-988
2008
Plasmodium vivax (A5KE01), Plasmodium vivax
Manually annotated by BRENDA team
Gracia, E.; Cortes, A.; Meana, J.J.; Garcia-Sevilla, J.; Herhsfield, M.S.; Canela, E.I.; Mallol, J.; Lluis, C.; Franco, R.; Casado, V.
Human adenosine deaminase as an allosteric modulator of human A(1) adenosine receptor: abolishment of negative cooperativity for [H](R)-pia binding to the caudate nucleus
J. Neurochem.
107
161-170
2008
Homo sapiens
Manually annotated by BRENDA team
Zaric, B.; Kuruc, V.; Milovancev, A.; Markovic, M.; Sarcev, T.; Canak, V.; Pavlovic, S.
Differential diagnosis of tuberculous and malignant pleural effusions: what is the role of adenosine deaminase?
Lung
186
233-240
2008
Homo sapiens
Manually annotated by BRENDA team
Tofovic, S.P.; Jackson, E.K.; Rafikova, O.
Adenosine deaminase-adenosine pathway in hemolysis-associated pulmonary hypertension
Med. Hypotheses
72
713-719
2009
Homo sapiens
Manually annotated by BRENDA team
Bhattacharjee, P.; Sharma, R.
Antithetical effects of corticosterone and dibutyryl cAMP on adenosine deaminase in the gastrointestinal tract of chicken during postnatal development
Mol. Cell. Biochem.
327
79-86
2009
Gallus gallus (Q5ZKP6), Gallus gallus
Manually annotated by BRENDA team
Alessandrini, L.; Ciuffreda, P.; Pavlovic, R.; Santaniello, E.
Activity of adenosine deaminase and adenylate deaminase on adenosine and 2, 3-isopropylidene adenosine: role of the protecting group at different pH values
Nucleosides Nucleotides Nucleic Acids
27
31-36
2008
Bos taurus
Manually annotated by BRENDA team
Baba, K.; Hoosen, A.A.; Langeland, N.; Dyrhol-Riise, A.M.
Adenosine deaminase activity is a sensitive marker for the diagnosis of tuberculous pleuritis in patients with very low CD4 counts
PLoS ONE
3
e2788
2008
Homo sapiens
Manually annotated by BRENDA team
Kim, S.H.; Kim, Y.K.; Park, H.W.; Kim, S.H.; Kim, S.H.; Ye, Y.M.; Min, K.U.; Park, H.S.
Adenosine deaminase and adenosine receptor polymorphisms in aspirin-intolerant asthma
Respir. Med.
103
356-363
2009
Homo sapiens (P00813), Homo sapiens
Manually annotated by BRENDA team
Dikensoy, O.; Fakili, F.; Elbek, O.; Uysal, N.
High adenosine deaminase activity in the pleural effusion of a patient with Legionnaires disease
Respirology
13
473-474
2008
Homo sapiens
Manually annotated by BRENDA team
Altug, N.; Yueksek, N.; Agaoglu, Z.T.; Keles, I.
Determination of adenosine deaminase activity in cattle naturally infected with Theileria annulata
Trop. Anim. Health Prod.
40
449-456
2008
Bos taurus
Manually annotated by BRENDA team
Assaife-Lopes, N.; Wengert, M.; Pinheiro, A.A.; Landgraf, S.S.; Paes-de-Carvalho, R.; Leao-Ferreira, L.R.; Caruso-Neves, C.
Adenosine deamination to inosine in isolated basolateral membrane from kidney proximal tubule: implications for modulation of the membrane-associated protein kinase A
Arch. Biochem. Biophys.
486
44-50
2009
Sus scrofa
Manually annotated by BRENDA team
Ho, M.C.; Cassera, M.B.; Madrid, D.C.; Ting, L.M.; Tyler, P.C.; Kim, K.; Almo, S.C.; Schramm, V.L.
Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases
Biochemistry
48
9618-9626
2009
Plasmodium berghei, Plasmodium falciparum, Plasmodium gallinaceum, Plasmodium knowlesi, Plasmodium vivax, Plasmodium cynomolgi
Manually annotated by BRENDA team
Kaminsky, Y.; Kosenko, E.
AMP deaminase and adenosine deaminase activities in liver and brain regions in acute ammonia intoxication and subacute toxic hepatitis
Brain Res.
1311
175-181
2010
Rattus norvegicus
Manually annotated by BRENDA team
Pinheiro, F.V.; Pimentel, V.C.; De Bona, K.S.; Scola, G.; Salvador, M.; Funchal, C.; Moretto, M.B.
Decrease of adenosine deaminase activity and increase of the lipid peroxidation after acute methotrexate treatment in young rats: protective effects of grape seed extract
Cell Biochem. Funct.
28
89-94
2010
Rattus norvegicus
Manually annotated by BRENDA team
Climent, N.; Martinez-Navio, J.M.; Gil, C.; Garcia, F.; Rovira, C.; Hurtado, C.; Miralles, L.; Gatell, J.M.; Gallart, T.; Mallol, J.; Lluis, C.; Franco, R.
Adenosine deaminase enhances T-cell response elicited by dendritic cells loaded with inactivated HIV
Immunol. Cell Biol.
87
634-639
2009
Bos taurus
Manually annotated by BRENDA team
Wu, X.H.; Zou, G.L.; Quan, J.M.; Wu, Y.D.
A theoretical study on the catalytic mechanism of Mus musculus adenosine deaminase
J. Comput. Chem.
31
2238-2247
2010
Mus musculus (P03958), Mus musculus
Manually annotated by BRENDA team
Zavialov, A.V.; Gracia, E.; Glaichenhaus, N.; Franco, R.; Zavialov, A.V.; Lauvau, G.
Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages
J. Leukoc. Biol.
88
279-290
2010
Homo sapiens (P00813), Homo sapiens (Q9NZK5), Homo sapiens
Manually annotated by BRENDA team
Niu, W.; Shu, Q.; Chen, Z.; Mathews, S.; Di Cera, E.; Frieden, C.
The role of Zn2+ on the structure and stability of murine adenosine deaminase
J. Phys. Chem. B
114
16156-16165
2010
Mus musculus (P03958), Mus musculus
Manually annotated by BRENDA team
Senger, M.R.; Rosemberg, D.B.; Seibt, K.J.; Dias, R.D.; Bogo, M.R.; Bonan, C.D.
Influence of mercury chloride on adenosine deaminase activity and gene expression in zebrafish (Danio rerio) brain
Neurotoxicology
31
291-296
2010
Danio rerio
Manually annotated by BRENDA team
da Silva, A.S.; Belle, L.P.; Bitencourt, P.E.; Souza, V.C.; Costa, M.M.; Oliveira, C.B.; Jaques, J.A.; Leal, D.B.; Moretto, M.B.; Mazzanti, C.M.; Lopes, S.T.; Monteiro, S.G.
Activity of the enzyme adenosine deaminase in serum, erythrocytes and lymphocytes of rats infected with Trypanosoma evansi
Parasitology
138
201-208
2010
Rattus norvegicus
Manually annotated by BRENDA team
Aghaei, M.; Karami-Tehrani, F.; Salami, S.; Atri, M.
Diagnostic value of adenosine deaminase activity in benign and malignant breast tumors
Arch. Med. Res.
41
14-18
2010
Homo sapiens
Manually annotated by BRENDA team
Kamat, S.S.; Bagaria, A.; Kumaran, D.; Holmes-Hampton, G.P.; Fan, H.; Sali, A.; Sauder, J.M.; Burley, S.K.; Lindahl, P.A.; Swaminathan, S.; Raushel, F.M.
Catalytic mechanism and three-dimensional structure of adenine deaminase
Biochemistry
50
1917-1927
2011
Plasmodium vivax
Manually annotated by BRENDA team
Da Silva, A.S.; Belle, L.P.; Bitencourt, P.E.; Perez, H.A.; Thome, G.R.; Costa, M.M.; Oliveira, C.B.; Teixeira, M.M.; Moretto, M.B.; Mazzanti, C.M.; Lopes, S.T.; Monteiro, S.G.
Trypanosoma evansi: adenosine deaminase activity in the brain of infected rats
Exp. Parasitol.
127
173-177
2011
Rattus norvegicus
Manually annotated by BRENDA team
Da Silva, A.S.; Pimentel, V.C.; Jaques, J.A.; Wolkmer, P.; Tavares, K.C.; Lazzarotto, C.R.; Miletti, L.C.; Schetinger, M.R.; Mazzanti, C.M.; Lopes, S.T.; Monteiro, S.G.
Biochemical detection of adenosine deaminase in Trypanosoma evansi
Exp. Parasitol.
128
298-300
2011
Trypanosoma evansi
Manually annotated by BRENDA team
Yadav, S.; Saxena, J.K.; Dwivedi, U.N.
Purification and characterization of Plasmodium yoelii adenosine deaminase
Exp. Parasitol.
129
368-374
2011
Plasmodium yoelii
Manually annotated by BRENDA team
Weizenmann, M.; Frasson, A.; de Barros, M.; Vieira, P.; Rosemberg, D.; De Carli, G.; Bogo, M.; Bonan, C.; Tasca, T.
Kinetic characterization and gene expression of adenosine deaminase in intact trophozoites of Trichomonas vaginalis
FEMS Microbiol. Lett.
319
115-124
2011
Trichomonas vaginalis
Manually annotated by BRENDA team
Pornbanlualap, S.; Chalopagorn, P.
Adenosine deaminase from Streptomyces coelicolor: Recombinant expression, purification and characterization
Protein Expr. Purif.
78
167-173
2011
Streptomyces coelicolor
Manually annotated by BRENDA team
Miller, D.; O'Brien, K.; Xu, H.; White, R.H.
Identification of a 5'-deoxyadenosine deaminase in Methanocaldococcus jannaschii and its possible role in recycling the radical S-adenosylmethionine enzyme reaction product 5'-deoxyadenosine
J. Bacteriol.
196
1064-1072
2013
Methanocaldococcus jannaschii (Q58936), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q58936)
Manually annotated by BRENDA team
Durak, Z.E.; Kocao?lu, E.H.; Oztuerk, B.
Static magnetic field inhibits adenosine deaminase activity in cancerous and noncancerous human gastric tissues
Cancer Biother. Radiopharm.
29
162-165
2014
Homo sapiens
Manually annotated by BRENDA team
Lougiakis, N.; Marakos, P.; Pouli, N.; Fragopoulou, E.; Tenta, R.
Synthesis of new nebularine analogues and their inhibitory activity against adenosine deaminase
Chem. Pharm. Bull.
63
134-142
2015
Bos taurus (P56658)
Manually annotated by BRENDA team
Lu, J.; Grenache, D.G.
Development of a rapid, microplate-based kinetic assay for measuring adenosine deaminase activity in body fluids
Clin. Chim. Acta
413
1637-1640
2012
Homo sapiens
Manually annotated by BRENDA team
Stuer-Lauridsen, B.; Nygaard, P.
Purine salvage in two halophilic archaea: characterization of salvage pathways and isolation of mutants resistant to purine analogs
J. Bacteriol.
180
457-463
1998
Halobacterium salinarum, Haloferax volcanii
Manually annotated by BRENDA team
Zimmermann, S.C.; Sadler, J.M.; ODaniel, P.I.; Kim, N.T.; Seley-Radtke, K.L.
Reverse carbocyclic fleximers: synthesis of a new class of adenosine deaminase inhibitors
Nucleosides Nucleotides Nucleic Acids
32
137-154
2013
Bos taurus (P56658)
Manually annotated by BRENDA team
Kandalkar, S.R.; Ramaiah, P.A.; Joshi, M.; Wavhal, A.; Waman, Y.; Raje, A.A.; Tambe, A.; Ansari, S.; De, S.; Palle, V.P.; Mookhtiar, K.A.; Deshpande, A.M.; Barawkar, D.A.
Modifications of flexible nonyl chain and nucleobase head group of (+)-erythro-9-(2s-hydroxy-3s-nonyl)adenine [(+)-EHNA] as adenosine deaminase inhibitors
Bioorg. Med. Chem.
25
5799-5819
2017
Bos taurus (P56658)
Manually annotated by BRENDA team
Qi, Y.; Li, Y.; Bao, J.J.
Development of a capillary electrophoresis method for analyzing adenosine deaminase and purine nucleoside phosphorylase and its application in inhibitor screening
Anal. Biochem.
506
31-44
2016
Homo sapiens, Mus musculus (P03958)
Manually annotated by BRENDA team
Jaruwat, A.; Riangrungroj, P.; Ubonprasert, S.; Sae-Ueng, U.; Kuaprasert, B.; Yuthavong, Y.; Leartsakulpanich, U.; Chitnumsub, P.
Crystal structure of Plasmodium falciparum adenosine deaminase reveals a novel binding pocket for inosine
Arch. Biochem. Biophys.
667
6-13
2019
Homo sapiens (P00813), Homo sapiens, Plasmodium falciparum (Q8IJA9), Plasmodium falciparum
Manually annotated by BRENDA team
Arun, K. G.; Sharanya, C.S.; Abhithaj, J.; Sadasivan, C.
Biochemical and computational insights of adenosine deaminase inhibition by Epigallocatechin gallate
Comput. Biol. Chem.
83
107111
2019
Bos taurus (P56658)
Manually annotated by BRENDA team
Fracasso, M.; Da Silva, A.S.; Baldissera, M.D.; Bottari, N.B.; Gabriel, M.E.; Piva, M.M.; Stedille, F.A.; Christ, R.; Rhoden, L.A.; Henker, L.C.; Moresch, V.M.; Schetinger, M.R.; Mendes, R.E.
Activities of ectonucleotidases and adenosine deaminase in platelets of cattle experimentally infected by Fasciola hepatica
Exp. Parasitol.
176
16-20
2017
Bos taurus (P56658), Bos taurus
Manually annotated by BRENDA team
Parra-Ruiz, J.; Ramos, V.; Duenas, C.; Coronado-Alvarez, N.M.; Cabo-Magadan, R.; Portillo-Tunon, V.; Vinuesa, D.; Munoz-Medina, L.; Hernandez-Quero, J.
Rational application of adenosine deaminase activity in cerebrospinal fluid for the diagnosis of tuberculous meningitis
Infection
43
531-535
2015
Homo sapiens
Manually annotated by BRENDA team
Ruggiero, V.; Cacace, E.; Era, B.; Fais, A.
Soluble adenosine deaminase activity in fibromyalgia syndrome
J. Musculoskelet. Pain
23
79-80
2015
Homo sapiens
-
Manually annotated by BRENDA team
da Silva, A.S.; Santurio, J.M.; Roza, L.F.; Bottari, N.B.; Galli, G.M.; Morsch, V.M.; Schetinger, M.R.C.; Baldissera, M.D.; Stefani, L.M.; Radavelli, W.M.; Tomasi, T.; Boiago, M.M.
Aflatoxins produced by Aspergillus parasiticus present in the diet of quails increase the activities of cholinesterase and adenosine deaminase
Microb. Pathog.
107
309-312
2017
Coturnix coturnix
Manually annotated by BRENDA team
Da Silva, A.S.; Baldissera, M.D.; Bottari, N.B.; Gabriel, M.E.; Rhoden, L.A.; Piva, M.M.; Christ, R.; Stedille, F.A.; Gris, A.; Morsch, V.M.; Schetinger, M.R.; Mendes, R.E.
Oxidative stress and changes in adenosine deaminase activity of cattle experimentally infected by Fasciola hepatica
Parasitology
144
520-526
2017
Bos taurus (P56658), Bos taurus
Manually annotated by BRENDA team
Gutierrez, A.M.; De La Cruz-Sanchez, E.; Montes, A.; Sotillo, J.; Gutierrez-Panizo, C.; Fuentes, P.; Tornel, P.L.; Cabezas-Herrera, J.
Easy and non-invasive disease detection in pigs by adenosine deaminase activity determinations in saliva
PLoS ONE
12
e0179299
2017
Sus scrofa (P58780), Sus scrofa
Manually annotated by BRENDA team
Pirincci, N.; Kaya, T.Y.; Kaba, M.; Ozan, T.; Gecit, I.; Oezveren, H.; Eren, H.; Ceylan, K.
Serum adenosine deaminase, catalase, and carbonic anhydrase activities in patients with renal cell carcinoma
Redox Rep.
22
252-256
2017
Homo sapiens
Manually annotated by BRENDA team
Doshi, K.M.; Loukanina, N.N.; Polowick, P.L.; Holbrook, L.A.
Seed specific expression and analysis of recombinant human adenosine deaminase (hADA) in three host plant species
Transgenic Res.
25
629-637
2016
Homo sapiens (P00813), Homo sapiens
Manually annotated by BRENDA team