Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.24.72: fibrolase

This is an abbreviated version!
For detailed information about fibrolase, go to the full flat file.

Word Map on EC 3.4.24.72

Reaction

Hydrolysis of -Ala14-/-Leu- in insulin B chain and -Lys413-/-Leu- in Aalpha-chain of fibrinogen =

Synonyms

3-203-fibrolase[3-serine], AfeE, Agkistrodon contortrix contortrix metalloproteinase, ALF, Alfimeprase, brevilysin L6, brevithrombolase, broad bean-fibrinolytic enzyme, CFR15-protease, fibrinolytic enzyme, fibrinolytic protease, Fibrinolytic proteinase, FIIa, neuwiedase, Non-hemorrhagic fibrinolytic metalloproteinase, plasmin, Proteinase, Agkistrodon contortrix contortrix venom metallo-, snake venom fibrinolytic enzyme, starase, UFEIII, VlF, wulfase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.72 fibrolase

Molecular Weight

Molecular Weight on EC 3.4.24.72 - fibrolase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
20800
-
1 * 20800, SDS-PAGE
22520
-
calculated molecular weight
22540
-
Agkistrodon contortrix, calculation from amino acid sequence
22710
22750
-
Agkistrodon contortrix, isoform fib2, calculation from amino acid sequence
22880
-
Agkistrodon contortrix, isoform fib1, calculation from amino acid sequence
22890
-
calculation from amino acid sequence
23000
23800
x * 23800, recombinant His-tagged alfimeprase, SDS-PAGE
25000
-
SDS-PAGE
34000
-
gel filtration
38000
-
gel filtration
42000
-
x * 42000, the enzyme exists in three isoforms of 42000, 48000 and 60000 Da, SDS-PAGE
43330
-
PEG-bound enzyme, gel filtration
47000
-
gel filtration
48000
55000
-
1 * 55000, SDS-PAGE
56043
-
1 * 56043, MALDI-TOF mass spectrometry
60000
additional information
-
amino acid sequence