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3.4.24.72: fibrolase

This is an abbreviated version!
For detailed information about fibrolase, go to the full flat file.

Word Map on EC 3.4.24.72

Reaction

Hydrolysis of -Ala14-/-Leu- in insulin B chain and -Lys413-/-Leu- in Aalpha-chain of fibrinogen =

Synonyms

3-203-fibrolase[3-serine], AfeE, Agkistrodon contortrix contortrix metalloproteinase, ALF, Alfimeprase, brevilysin L6, brevithrombolase, broad bean-fibrinolytic enzyme, CFR15-protease, fibrinolytic enzyme, fibrinolytic protease, Fibrinolytic proteinase, FIIa, neuwiedase, Non-hemorrhagic fibrinolytic metalloproteinase, plasmin, Proteinase, Agkistrodon contortrix contortrix venom metallo-, snake venom fibrinolytic enzyme, starase, UFEIII, VlF, wulfase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.72 fibrolase

KM Value

KM Value on EC 3.4.24.72 - fibrolase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0000654
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
-
-
0.3266
azocasein
-
at pH 7.8 and 37°C
-
1.37
D-Val-Leu-Lys-4-nitroanilide
-
at pH 7.4 and 37°C
0.00000739
His-Thr-Glu-Ala-Leu-Val-Thr-Ser
-
-
0.00000338
His-Thr-Glu-Arg-Leu-Val-Thr-Ser
-
-
0.00000937
His-Thr-Glu-Asn-Leu-Val-Thr-Ser
-
-
0.00000164
His-Thr-Glu-Glu-Leu-Val-Thr-Ser
-
-
0.00000415
His-Thr-Glu-His-Leu-Val-Thr-Ser
-
-
0.00000528
His-Thr-Glu-Leu-Leu-Val-Thr-Ser
-
-
0.00000579 - 0.000579
His-Thr-Glu-Lys-Leu-Val-Thr-Ser
0.00000247
His-Thr-Glu-Lys-Phe-Val-Thr-Ser
-
-
0.00000113
His-Thr-Glu-Phe-Leu-Val-Thr-Ser
-
-
0.00000391
His-Thr-Glu-Pro-Leu-Val-Thr-Ser
-
-
0.00000832
His-Thr-Glu-Ser-Leu-Val-Thr-Ser
-
-
0.00000138
Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val
-
-
0.000000242
low molecular weight kininogen
-
-
-
additional information
additional information
-
analysis of kinetic and equilibrium binding parameters of streptokinase-plasmin catalytic complex formation and its regulation by effectors 6-AHA and benzamidine
-