3.4.22.41: cathepsin F
This is an abbreviated version!
For detailed information about cathepsin F, go to the full flat file.
Word Map on EC 3.4.22.41
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3.4.22.41
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cathepsins
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diagnostics
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westermani
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viroid
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paragonimus
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f-like
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food industry
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metalloproteinase-10
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cystatin-like
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viverrini
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medicine
- 3.4.22.41
- cathepsins
- diagnostics
- westermani
- viroid
- paragonimus
-
f-like
- food industry
- metalloproteinase-10
-
cystatin-like
- viverrini
- medicine
Reaction
The recombinant enzyme cleaves synthetic substrates with Phe and Leu (better than Val) in P2, with high specificity constant (kcat/Km) comparable to that of cathepsin L =
Synonyms
cat F, CatF, cathepsin f, cathepsin F-1, CATSF, CF-1, CF-11, CF-4, CF-6, cf1, CtF, CTSF, Ov-CF-1, PwCP1, PwCP10, PwCP11, PwCP2, PwCP3, PwCP4, PwCP5, PwCP6, PwCP7, PwCP8, PwCP9, Tci-CF-1
ECTree
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Cloned
Cloned on EC 3.4.22.41 - cathepsin F
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DNA and amino acid sequence determination and analysis, sequence comparison and phylogenetic analysis
enhanced production and release of cathepsins in tumor cells leads to tumor cell growth, invasion and metastasis
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expressed in Escherichia coli DH5alphaMCR cells using the pGEX-4 T-1 expression vector system
PCR with primers specific for the Camellia sinensis cathepsin F gene, 5'- and 3'-RACE used to clone and identify a coding sequence of 981 bp (AY821800). The Ov-cf-1 gene is organized into 7 exons. Phylogenetic analysis confirms relationship of Ov-CF-1 with other cathepsin F proteases.