3.4.22.41: cathepsin F

This is an abbreviated version!
For detailed information about cathepsin F, go to the full flat file.

Word Map on EC 3.4.22.41

3.4.22.41

cathepsins

diagnostics

westermani

viroid

paragonimus

f-like

food industry

metalloproteinase-10

cystatin-like

viverrini

medicine

Reaction

The recombinant enzyme cleaves synthetic substrates with Phe and Leu (better than Val) in P2, with high specificity constant (kcat/Km) comparable to that of cathepsin L =

Synonyms

cat F, CatF, cathepsin f, cathepsin F-1, CATSF, CF-1, CF-11, CF-4, CF-6, cf1, CtF, CTSF, Ov-CF-1, PwCP1, PwCP10, PwCP11, PwCP2, PwCP3, PwCP4, PwCP5, PwCP6, PwCP7, PwCP8, PwCP9, Tci-CF-1

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.41 cathepsin F

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Results	in table
9	Activating Compound
53	AA Sequence
6	Application
1	CAS Registry Number
20	Cloned(Commentary)
2	Crystallization (Commentary)
46	Disease/ Diagnostics
4	Expression
3	General Information
28	Inhibitors
4	kcat/KM [mM/s]
6	KM Value [mM]
16	Localization
3	Metals/Ions
17	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
40	Organism
2	PDB ID
7	pH Optimum
5	pH Range
7	pH Stability
2	pI Value
7	Posttranslational Modification
2	Protein Variants
6	Purification (Commentary)
2	Reaction
2	Reaction Type
30	Reference
1	Renatured (Commentary)
87	Source Tissue
4	Specific Activity [micromol/min/mg]
2	Storage Stability
47	Substrates and Products (Substrate)
5	Subunits
33	Synonyms
1	Temperature Optimum [°C]
6	Turnover Number [1/s]

pH Stability

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pH Stability on EC 3.4.22.41 - cathepsin F

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4 - 8

Clonorchis sinensis

isozyme CF-4 is relatively stable at slight acidic and neutral pHs, but is comparatively unstable in acidic pHs, isozyme CF-11 is stable at acidic pHs, but is highly unstable in neutral and alkaline pH values

709866

4.5

2 entries

5.5

Opisthorchis viverrini

cathepsin F zymogen is inactive at pH 5.5

708053

7.2

Homo sapiens

Q9UBX1

half-life 2 min

137262