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3.4.21.78: granzyme A

This is an abbreviated version!
For detailed information about granzyme A, go to the full flat file.

Word Map on EC 3.4.21.78

Reaction

Hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: -Arg-/-, -Lys-/- >> -Phe-/- in small molecule substrates =

Synonyms

Autocrine thymic lymphoma granzyme-like serine protease, CTL tryptase, CTLA3, Cytotoxic T lymphocyte serine protease, GrA, Gzm A, Gzma, GzmA/K, H factor, Hanukkah factor, HuTPS, T-cell associated protease 1, T-cell derived serine proteinase 1, TSP-1

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.78 granzyme A

Sequence

topprint

Sequence on EC 3.4.21.78 - granzyme A

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
GRAA_BOVIN
258
0
28070
Swiss-Prot
Secretory Pathway (Reliability: 1)
GRAA_HUMAN
262
0
28999
Swiss-Prot
Secretory Pathway (Reliability: 1)
GRAA_MOUSE
260
0
28599
Swiss-Prot
Secretory Pathway (Reliability: 2)
A9UMI2_XENTR
219
0
23947
TrEMBL
other Location (Reliability: 5)
Q7T0T6_XENLA
277
1
30631
TrEMBL
other Location (Reliability: 5)
D8WWX5_CYPCA
257
0
28598
TrEMBL
-
GRAM_HUMAN
257
0
27545
Swiss-Prot
-
Q8CJF4_RAT
261
0
28563
TrEMBL
-