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3.4.21.78: granzyme A

This is an abbreviated version!
For detailed information about granzyme A, go to the full flat file.

Word Map on EC 3.4.21.78

Reaction

Hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: -Arg-/-, -Lys-/- >> -Phe-/- in small molecule substrates =

Synonyms

Autocrine thymic lymphoma granzyme-like serine protease, CTL tryptase, CTLA3, Cytotoxic T lymphocyte serine protease, GrA, Gzm A, Gzma, GzmA/K, H factor, Hanukkah factor, HuTPS, T-cell associated protease 1, T-cell derived serine proteinase 1, TSP-1

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.78 granzyme A

Organism

Organism on EC 3.4.21.78 - granzyme A

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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
sequence contains a putative signal peptide, eight consensus cysteine residues, one conserved IIGG motif and three conserved residues as central elements of the GzmA/K active site
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
gene gzmA
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team