3.4.21.78: granzyme A
This is an abbreviated version!
For detailed information about granzyme A, go to the full flat file.
Word Map on EC 3.4.21.78
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3.4.21.78
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thrombospondin-1
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angiogenesis
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endothelial
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perforin
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killer
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granule
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angiogenic
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antiangiogenic
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cytolytic
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matricellular
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metastasis
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collagen
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microvessels
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t-cells
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microvascular
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integrins
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fibrosis
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fibronectin
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cd8
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tgf-beta1
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neovascularization
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fasl
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fgf-2
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corneal
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alphavbeta3
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exocytosis
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ctl-mediated
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factor-beta
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bfgf
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medicine
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caspase-independent
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angiogenesis-related
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granule-associated
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integrin-associated
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angiostatic
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proangiogenic
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metronomic
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properdin
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endostatin
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granulysin
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tregs
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lymphocyte-mediated
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lymphokine-activated
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ifn-gamma
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vegf-a
- 3.4.21.78
- thrombospondin-1
- angiogenesis
- endothelial
- perforin
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killer
- granule
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angiogenic
-
antiangiogenic
-
cytolytic
-
matricellular
- metastasis
- collagen
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microvessels
- t-cells
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microvascular
- integrins
- fibrosis
- fibronectin
- cd8
- tgf-beta1
- neovascularization
- fasl
- fgf-2
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corneal
- alphavbeta3
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exocytosis
-
ctl-mediated
- factor-beta
- bfgf
- medicine
-
caspase-independent
-
angiogenesis-related
-
granule-associated
-
integrin-associated
-
angiostatic
-
proangiogenic
-
metronomic
- properdin
- endostatin
-
granulysin
-
tregs
-
lymphocyte-mediated
-
lymphokine-activated
- ifn-gamma
- vegf-a
Reaction
Hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: -Arg-/-, -Lys-/- >> -Phe-/- in small molecule substrates =
Synonyms
Autocrine thymic lymphoma granzyme-like serine protease, CTL tryptase, CTLA3, Cytotoxic T lymphocyte serine protease, GrA, Gzm A, Gzma, GzmA/K, H factor, Hanukkah factor, HuTPS, T-cell associated protease 1, T-cell derived serine proteinase 1, TSP-1
ECTree
3.4.21.78 granzyme AAdvanced search results
results (
results (General Stability
General Stability on EC 3.4.21.78 - granzyme A
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GENERAL STABILITY 
ORGANISM
UNIPROT
LITERATURE
extracellular granzyme A circulates in the mature conformation and is bound to proteoglycans that protect it against inactivation by protease inhibitors
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