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3.4.21.78: granzyme A

This is an abbreviated version!
For detailed information about granzyme A, go to the full flat file.

Word Map on EC 3.4.21.78

Reaction

Hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: -Arg-/-, -Lys-/- >> -Phe-/- in small molecule substrates =

Synonyms

Autocrine thymic lymphoma granzyme-like serine protease, CTL tryptase, CTLA3, Cytotoxic T lymphocyte serine protease, GrA, Gzm A, Gzma, GzmA/K, H factor, Hanukkah factor, HuTPS, T-cell associated protease 1, T-cell derived serine proteinase 1, TSP-1

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.78 granzyme A

Purification

Purification on EC 3.4.21.78 - granzyme A

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
recombinant enzyme
-
recombinant His-tagged enzyme from Escherichia coli by nickel affinity chromatography