3.2.1.62: glycosylceramidase
This is an abbreviated version!
For detailed information about glycosylceramidase, go to the full flat file.
Word Map on EC 3.2.1.62
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3.2.1.62
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lactose
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sucrase-isomaltase
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enterocytes
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brush
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jejunum
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pro-lph
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microvillus
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brush-border
-
sucrase
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hypolactasia
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disaccharidase
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adult-type
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maltase-glucoamylase
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enterocyte-specific
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mannose-rich
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beta-glycosidase
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transport-competent
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3.4.11.7
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medicine
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non-persistence
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crypt-villus
- 3.2.1.62
- lactose
- sucrase-isomaltase
- enterocytes
-
brush
- jejunum
-
pro-lph
- microvillus
-
brush-border
- sucrase
- hypolactasia
- disaccharidase
-
adult-type
- maltase-glucoamylase
-
enterocyte-specific
-
mannose-rich
-
beta-glycosidase
-
transport-competent
-
3.4.11.7
- medicine
-
non-persistence
-
crypt-villus
Reaction
Synonyms
cerebrosidase, EGC, EGCII, EGCrP1, Egh1, endo-glycoceramidase II, endoglycoceramidase II, endoglycoceramidase-related protein 1, ergosteryl-beta-glucosidase, Gcase, glucocerebrosidase, glycosyl ceramide glycosylhydrolase, glycosyl-N-acylsphingosine glycohydrolase, glycosylceramidase, KLotho lactase phlorizin hydrolase, Klotho-related protein, lactase phlorizin hydrolase, lactase-phlorizin hydrolase, LCT, LPH, LPH1, phloretin-glucosidase, phloridzin glucosidase, phlorizin beta-glucosidase, phlorizin hydrolase, Yir007w
ECTree
3.2.1.62 glycosylceramidaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 3.2.1.62 - glycosylceramidase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(2-hydroxymethylphenyl)-beta-D-glucopyranoside + H2O
2-hydroxymethylphenol + beta-D-glucose
3'-fucosyllactose + H2O
beta-D-glucose + 3-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranose
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only oligosaccharides containing galactose as the glycone in beta-linkage hydrolysed
-
?
4-O-beta-D-galactopyranosyl-D-fructoside + H2O
beta-D-galactose + D-fructose
-
very low activity
-
?
4-O-beta-D-galactopyranosyl-D-N-acetylglucosamine + H2O
beta-D-galactose + N-acetylglucosamine
-
poor activity
-
?
galactosylsphingosine + H2O
beta-D-galactose + sphingosine
-
very low activity
-
?
glucosylsphingosine + H2O
beta-D-glucose + N-acylsphingosine
-
very low activity
-
?
lactosylceramide + H2O
beta-D-glucose + galactosylceramide
-
low activity
-
?
(2-hydroxymethylphenyl)-beta-D-glucopyranoside + H2O
2-hydroxymethylphenol + beta-D-glucose
-
low activity
-
?
(2-hydroxymethylphenyl)-beta-D-glucopyranoside + H2O
2-hydroxymethylphenol + beta-D-glucose
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salicin
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
-
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
-
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
-
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
-
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
-
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
-
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
best substrate
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
4fold higher activity for the N- and O-glycosylated than for the N-glycosylated molecule
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
-
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
best substrate
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
two enzymatic activities, one for lactose- and one for phlorizin-and lactose-hydrolysis
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
best substrate
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
hydrolysis located on a specific active site for lactose hydrolysis
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
two enzymatic activities, one for lactose- and one for phlorizin-and lactose-hydrolysis
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
two enzymatic activities, one for lactose- and one for phlorizin-and lactose-hydrolysis
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
Ovis aries aries
-
hydrolysis located on a specific active site for lactose hydrolysis
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
Ovis aries aries
-
acts on dietary glycosides before absorption
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
-
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
best substrate
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
best substrate
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
acts on dietary glycosides before absorption
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
two enzymatic activities, one for lactose- and one for phlorizin-and lactose-hydrolysis
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
two enzymatic activities, one for lactose- and one for phlorizin-and lactose-hydrolysis
-
?
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O
D-galactose + beta-D-glucose
-
two enzymatic activities, one for lactose- and one for phlorizin-and lactose-hydrolysis
-
?
4-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
cellobiose
-
?
4-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
cellobiose
-
?
4-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
cellobiose
-
?
4-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
cellobiose
-
?
4-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
cellobiose
-
?
4-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
cellobiose
-
?
4-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
cellobiose
-
?
4-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
cellobiose
-
?
6-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
gentiobiose
-
?
6-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
gentiobiose
-
?
6-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
low activity
-
?
6-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
gentiobiose
-
?
6-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
low activity
-
?
6-O-beta-D-glucopyranosyl-D-glucose + H2O
beta-D-glucose + D-glucose
-
gentiobiose
-
?
oligoglycosylglucosyl-(1->1)-ceramide + H2O
ceramide + oligoglycosylglucose
-
-
-
?
oligoglycosylglucosyl-(1->1)-ceramide + H2O
ceramide + oligoglycosylglucose
-
-
-
?
phlorizin + H2O
phloretin + beta-D-glucose
-
hydrolysis located on a specific active site for phlorizin hydrolysis
-
?
phlorizin + H2O
phloretin + beta-D-glucose
Ovis aries aries
-
hydrolysis located on a specific active site for phlorizin hydrolysis
-
?
phlorizin + H2O
phloretin + beta-D-glucose
-
only substrate that is hydrolysed at the active site for phlorizin hydrolysis
-
?
phlorizin + H2O
phloretin + beta-D-glucose
-
5% of the activity of lactose hydrolysis
-
?
phlorizin + H2O
phloretin + beta-D-glucose
-
hydrolysis located on a specific active site for phlorizin hydrolysis
-
?
additional information
?
-
-
absorption of quercetin-3-glucoside requires hydrolysis by the enzyme, absorption of quercetin-4-glucoside requires both an interaction with sodium-dependent glucose transporter and hydrolysis by the enzyme
-
-
?
additional information
?
-
-
enzyme is a major determinant of intestinal absorption of quercetin-3-glucoside
-
-
?
additional information
?
-
-
enzyme plays a major role in metabolism of glycosylated phytochemicals
-
-
?
