3.2.1.62: glycosylceramidase
This is an abbreviated version!
For detailed information about glycosylceramidase, go to the full flat file.
Word Map on EC 3.2.1.62
-
3.2.1.62
-
lactose
-
sucrase-isomaltase
-
enterocytes
-
brush
-
jejunum
-
pro-lph
-
microvillus
-
brush-border
-
sucrase
-
hypolactasia
-
disaccharidase
-
adult-type
-
maltase-glucoamylase
-
enterocyte-specific
-
mannose-rich
-
beta-glycosidase
-
transport-competent
-
3.4.11.7
-
medicine
-
non-persistence
-
crypt-villus
- 3.2.1.62
- lactose
- sucrase-isomaltase
- enterocytes
-
brush
- jejunum
-
pro-lph
- microvillus
-
brush-border
- sucrase
- hypolactasia
- disaccharidase
-
adult-type
- maltase-glucoamylase
-
enterocyte-specific
-
mannose-rich
-
beta-glycosidase
-
transport-competent
-
3.4.11.7
- medicine
-
non-persistence
-
crypt-villus
Reaction
Synonyms
cerebrosidase, EGC, EGCII, EGCrP1, Egh1, endo-glycoceramidase II, endoglycoceramidase II, endoglycoceramidase-related protein 1, ergosteryl-beta-glucosidase, Gcase, glucocerebrosidase, glycosyl ceramide glycosylhydrolase, glycosyl-N-acylsphingosine glycohydrolase, glycosylceramidase, KLotho lactase phlorizin hydrolase, Klotho-related protein, lactase phlorizin hydrolase, lactase-phlorizin hydrolase, LCT, LPH, LPH1, phloretin-glucosidase, phloridzin glucosidase, phlorizin beta-glucosidase, phlorizin hydrolase, Yir007w
ECTree
Advanced search results
Subunits
Subunits on EC 3.2.1.62 - glycosylceramidase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
dimer
monomer
additional information
-
1 * 160000, SDS-PAGE, mature brush-border form after proteolytic cleavage of the precursor form
monomer
-
1 * 160000, SDS-PAGE, mature brush-border form after proteolytic cleavage of the precursor form
-
region LAC236 between R1647 and T1882 is implicated in the dimerization processof pro-enzyme
additional information
-
LPH encompasses four homologous domains, which presumably have evolved from two subsequent duplications of one ancestral gene, domain organization, overview. The profragment, LPHalpha, comprises homologous domains I and II and functions as an intramolecular chaperone in the context of the brush-border LPHbeta region of LPH. Inter-relationship between homologous domains III and IV of LPHbeta implication in the overall structure, function, and trafficking of LPH, overview. Isolated homologous domain III is transport-competent per se and sorted to the apical membrane in polarized cells. Nevertheless, it neither dimerizes nor acquires complete phlorizin hydrolase activity
additional information
-
phlorizin hydrolysis occurs at region III of enzyme, lactase hydrolysis occurs at region IV