3.2.1.62: glycosylceramidase

This is an abbreviated version!
For detailed information about glycosylceramidase, go to the full flat file.

Word Map on EC 3.2.1.62

3.2.1.62

lactose

sucrase-isomaltase

enterocytes

brush

jejunum

pro-lph

microvillus

brush-border

sucrase

hypolactasia

disaccharidase

adult-type

maltase-glucoamylase

enterocyte-specific

mannose-rich

beta-glycosidase

transport-competent

3.4.11.7

medicine

non-persistence

crypt-villus

Reaction

Synonyms

cerebrosidase, EGC, EGCII, EGCrP1, Egh1, endo-glycoceramidase II, endoglycoceramidase II, endoglycoceramidase-related protein 1, ergosteryl-beta-glucosidase, Gcase, glucocerebrosidase, glycosyl ceramide glycosylhydrolase, glycosyl-N-acylsphingosine glycohydrolase, glycosylceramidase, KLotho lactase phlorizin hydrolase, Klotho-related protein, lactase phlorizin hydrolase, lactase-phlorizin hydrolase, LCT, LPH, LPH1, phloretin-glucosidase, phloridzin glucosidase, phlorizin beta-glucosidase, phlorizin hydrolase, Yir007w

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.62 glycosylceramidase

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Results	in table
11	Activating Compound
15	AA Sequence
7	Application
1	CAS Registry Number
16	Cloned(Commentary)
3	Crystallization (Commentary)
94	Disease/ Diagnostics
9	General Information
2	General Stability
1	IC50 Value
62	Inhibitors
4	kcat/KM [mM/s]
5	Ki Value [mM]
73	KM Value [mM]
27	Localization
1	Metals/Ions
27	Molecular Weight [Da]
76	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
125	Organism
6	Pathway
15	pH Optimum
2	pH Range
2	pH Stability
13	Posttranslational Modification
23	Protein Variants
22	Purification (Commentary)
4	Reaction
9	Reaction Type
56	Reference
46	Source Tissue
26	Specific Activity [micromol/min/mg]
2	Storage Stability
198	Substrates and Products (Substrate)
16	Subunits
77	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
8	Temperature Stability [°C]
17	Turnover Number [1/s]

pH Optimum

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pH Optimum on EC 3.2.1.62 - glycosylceramidase

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Saccharomyces cerevisiae

750706

5.2

Mus musculus

hydrolysis of galactosyl- or glucosylceramide in the presence of taurodeoxycholate

208758

5.2 - 5.6

Macaca radiata

phlorizin activity in acetate buffer

208763

5.5

2 entries

5.5 - 5.7

Mus musculus

hydrolysis of disaccharides or artificial substrates

5.6

5.6 - 6.2

5.8 - 6

6 - 7

C6-4-nitrobenzo-2-oxa-1,3-diazole-glucosylceramide as substrate

680835

7.5

2 entries