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3.2.1.1: alpha-amylase

This is an abbreviated version!
For detailed information about alpha-amylase, go to the full flat file.

Word Map on EC 3.2.1.1

Reaction

(alpha-D-glucopyranosyl-(1-4))n-alpha-D-glucopyranose
+
H2O
=
(alpha-D-glucopyranosyl-(1-4))n-m-alpha-D-glucopyranose
 +
(alpha-D-glucopyranosyl-(1-4))m-alpha-D-glucopyranose

Synonyms

1,4-alpha-D-glucan glucanohydrolase, 1,4-alpha-D-glucan glucanohydrolase and endoamylase, 1,4-alpha-D-glucan-glucanohydrolase, ABA, acid-stable amylase, acidic amylase, AGXA, AHA, alkaline alpha-amylase, alkalophilic Bacillus alpha-amylase, alpha amylase, alpha amylase 1, alpha-(1,4)-D-glucan glucanohydrolase, alpha-1,4 glucan-glucanohydrolase, alpha-1,4-glucan-4-glucanohydrolase, alpha-1-4 D-glucan glucanohydrolase, alpha-amylase, alpha-amylase 1, alpha-amylase 2, alpha-amylase 3, alpha-amylase A4, alpha-amylase Aasp, alpha-amylase AI, alpha-amylase AOA, Alpha-amylase carcinoid, alpha-amylase CMA, alpha-amylase gt, alpha-amylase HA, alpha-amylase I, alpha-amylase II, alpha-amylase PA, alpha-amylase PPA, alpha-amylase type A isozyme, alpha-amylase type II, alpha-amylase ZSA, alpha-amylases 1, AMF-3, ami, Amy, Amy B, Amy c6, Amy I, Amy II, Amy-1E, amy-CS2, Amy-E, Amy-FC1, AMY1, AMY121, AMY2, Amy3, amy5, Amy7C, AmyA, AmyB, AmyC, AmyCR, AmyD, AmyD-1, AmyE, AmyH, AmyI-1, AmyI3C6, AmyK, AmyK38, AmyL, Amyl III, amylase AI, amylase AII, amylase I, Amylase THC 250, amylase, alpha-, Amylopsin, amylopullulanase, AmyN26, AmyP, AmyQ, AmyS, AmyUS100, AmyUS100DELTAIG, AmyZ2, AOA, AoA1, AoA2, ApkA, Apu, B4168_3135, Ba-amy, BAA, Bacillus licheniformis alpha-amylase, Bactosol TK, barley alpha-amylase 1, BBG7_0117, BGTG-1, BH072alpha-amylase, BHA, BiLA, BLA, Blamy-I, bllj_0710, BMA.2, BSA-2, Bsamy-I, BSTA, Buclamase, Ca2+-independent alpha-amylase gt, CcAmy, CCAP, Clarase, Clone 103, Clone 168, Clone PHV19, Clones GRAMY56 and 963, cold-active alpha-amylase, cold-adapted alpha-amylase, ComA, crustacean cardioactive peptide, diastase, endo-1,4-alpha-D-glucan glucanohydrolase, endo-1,4-alpha-D-glucan glucohydrolase, endo-1,4-alpha-D-glucanohydrolase, endoamylase, FORILASE NTL alpha-amylase, Fortizyme, Fungamyl 800 L, G 995, G6-amylase, GH13Amy-1, GH13Amy-2, glycogenase, Gt-amy, HaAmy1, HaAmy2, haloalkaline alpha-amylase, HAS, HdAmyI, High pI alpha-amylase, HPA, HSA, HSAmy, HSAmy-ar, htur2110, human salivary alpha-amylase, hyperthermophilic alpha-amylase, Isozyme 1B, Kleistase L 1, KRA, LAMY, liquozyme, LLF-alpha-amylase, Low pI alpha-amylase, MalA, maltogenic amylase, maltohexaose-producing alpha-amylase, maltotriose-producing alpha-amylase, MAmy, Maxamyl, Maxilase, Meiotic expression upregulated protein 30, MJA1, More, N8 alpha-amylase, neutral amylase, Pancreatic alpha-amylase, PFTA, Pivozin, PPA, PPA-I, PPA-II, psychrophilic alpha amylase, Ptyalin, raw-starch-digesting alpha-amylase, RB5AMG_01539, Rbamy5, RBLA, RBSA-1, ROAmy, Ruminococcus bromii intermediary alpha-amylase 5, Saci_1162, salt-tolerant alpha-amylase, ScAmy43, Sfamy, Spitase CP 1, SSO1172, SusG, TAA, TaAmy3, Taka-amylase A, Takatherm, TcAmy, TdAmyA, tergal gland protein-1, TfAmy48, Thermamyl, Thermolase, thermostable alpha-amylase, TO_amyl, Tp-AmyS, TVA II, VAAmy1, VAAmy2, VrAmy, ZSA

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.1 alpha-amylase

IC50 Value

IC50 Value on EC 3.2.1.1 - alpha-amylase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.000996 - 88.99
acarbose
0.17
apigenin-7-glucoside
Sus scrofa
-
IC50 is 0.17 mM
0.37 - 4.8
caffeic acid
0.07 - 1.4
chlorogenic acid
2
cynarin
Sus scrofa
-
IC50 is above 2.0 mM
14
dihydrocaffeic acid
Sus scrofa
-
IC50 is above 14.0 mM
0.048
eupafolin
Homo sapiens
-
a flavone, pH 6.0, room temperature
5
ferulic acid
Sus scrofa
-
IC50 is above 5.0 mM
0.0196 - 0.44
fisetin
0.56
isochlorogenic acid
Sus scrofa
-
IC50 is 0.56 mM
0.0184 - 0.17
luteolin
0.28
luteolin-7-glucoside
Sus scrofa
-
IC50 is 0.28 mM
0.0302
myricetin
Homo sapiens
-
a flavonol, pH 6.0, room temperature
0.000008 - 0.00579
proteinaceous inhibitor from wheat WI-1
-
0.00103
proteinaceous inhibitor from wheat WI-3
Ephestia kuehniella
isozyme Amy3, in 0.1 M Britton-Robinson buffer at pH 8.0, at 26°C
-
0.0102
quercetagetin
Homo sapiens
-
a flavonol, pH 6.0, room temperature
0.0214
quercetin
Homo sapiens
-
a flavonol, pH 6.0, room temperature
13 - 26.5
quinic acid
1.4
rosmarinic acid
Sus scrofa
-
IC50 is 1.4 mM
0.00964
scutellarein
Homo sapiens
-
a flavone, pH 6.0, room temperature
6.7
Sinapic acid
Sus scrofa
-
IC50 is above 6.7 mM
0.14
Tannic acid
Sus scrofa
-
IC50 is 0.14 mM
5
Zn2+
Geobacillus sp.
-
at 80°C and pH 5.0
additional information
acarviostatin 103