3.1.6.2: steryl-sulfatase

This is an abbreviated version!
For detailed information about steryl-sulfatase, go to the full flat file.

Word Map on EC 3.1.6.2

3.1.6.2

women

testosterone

androgen

adrenal

cortisol

estradiol

estrogen

androstenedione

sulphate

globulin

polycystic

ovary

fsh

x-linked

ovarian

postmenopausal

ichthyosis

progesterone

acth

aromatase

hyperandrogenism

neurosteroids

hirsutism

menstrual

hormone-binding

prolactin

luteinizing

17-hydroxyprogesterone

premenopausal

adrenarche

sulfotransferase

hormone-dependent

sulfamate

endocrinology

hyperandrogenemia

17beta-hydroxysteroid

hypothalamic-pituitary-adrenal

pubertal

pharmacology

21-hydroxylase

alpha-hydroxyprogesterone

17beta-hsds

dhea-s

virilization

tanner

11-deoxycortisol

allopregnanolone

sulfatases

kallmann

medicine

analysis

pregs

incidentalomas

Reaction

3beta-hydroxyandrost-5-en-17-one 3-sulfate

Synonyms

3-beta-hydroxysteroid sulfate sulfatase, arylsufatase, arylsulfatase C, ASC, AtsA, cholesterol sulfate sulfohydrolase, CHS-ase, dehydroepiandrosterone sulfatase, dehydroepiandrosterone sulfate sulfatase, DHEAS, E1-STS, ES, estrone sulfatase, More, neurosteroid sulfatase, NSS, oestrone sulfatase, phenolic steroid sulfatase, pregnenolone sulfatase, steroid 3-sulfatase, steroid sulfatase, steroid sulfate sulfohydrolase, steroid sulphatase, sterol sulfatase, sterolsulfate sulfohydrolase, Steryl-sulfate sulfohydrolase, STS, sulfatase, sterol

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.6 Sulfuric-ester hydrolases

3.1.6.2 steryl-sulfatase

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Results	in table
21	Activating Compound
41	AA Sequence
39	Application
1	CAS Registry Number
15	Cloned(Commentary)
6	Crystallization (Commentary)
4500	Disease/ Diagnostics
6	Expression
10	General Information
1	General Stability
98	IC50 Value
328	Inhibitors
25	Ki Value [mM]
76	KM Value [mM]
57	Localization
6	Metals/Ions
45	Molecular Weight [Da]
90	Natural Substrates/ Products (Substrates)
134	Organism
2	Pathway
1	PDB ID
33	pH Optimum
3	pH Range
2	pI Value
15	Posttranslational Modification
35	Protein Variants
21	Purification (Commentary)
1	Reaction
1	Reaction Type
131	Reference
216	Source Tissue
15	Specific Activity [micromol/min/mg]
4	Storage Stability
251	Substrates and Products (Substrate)
14	Subunits
114	Synonyms
1	Systematic Name
15	Temperature Optimum [°C]
1	Temperature Range [°C]
15	Temperature Stability [°C]
1	Turnover Number [1/s]

KM Value

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KM Value on EC 3.1.6.2 - steryl-sulfatase

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0.02

16alpha-hydroxydehydroepiandrosterone 3-sulfate

Homo sapiens

135603

0.0019 - 0.0043

17beta-estradiol sulfate

3 entries

0.217

4-methylumbelliferylsulfate

Homo sapiens

135600

0.007 - 10.2

4-nitrophenyl sulfate

4 entries

0.00313

androstenediol 3-sulfate

Homo sapiens

135614

0.00062 - 0.0057

cholesterol 3-sulfate

4 entries

0.0067

Cholesterol sulfate

Homo sapiens

pH 6.4, 37°C

656643

0.014

dehydroandrosterone 3-sulfate

Homo sapiens

135599

0.0029 - 0.113

dehydroepiandrosterone 3-sulfate

13 entries

0.0017 - 0.013

dehydroepiandrosterone sulfate

8 entries

0.026

epiandrosterone 3-sulfate

Pseudomonas aeruginosa

P51691

pH 8.8, 37°C

750395

0.005 - 0.0506

esterone 3-sulfate

2 entries

0.0034 - 0.035

Estrone 3-sulfate

6 entries

0.00215 - 0.07275

Estrone sulfate

4 entries

0.1 - 2.5

methylumbelliferyl sulfate

5 entries

0.007 - 1600

p-Nitrophenyl sulfate

4 entries

p-nitrophenylsulfate

Homo sapiens

135604

0.00018 - 0.0018

pregnenolone 3-sulfate

4 entries

0.05

testosterone 17-sulfate

Pseudomonas aeruginosa

P51691

pH 8.8, 37°C

750395

0.0045 - 0.088

testosterone 3-sulfate

10 entries