Reference on EC 3.1.6.2 - steryl-sulfatase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Daniel, W.L.
Arylsulfatase C and the streroid sulfatases
Isozymes Curr. Top. Biol. Med. Res.
12
189-228
1985
Aspergillus nidulans, Bos taurus, Chlamydomonas reinhardtii, Homo sapiens, Mus musculus, Pseudomonas aeruginosa, Rattus norvegicus
Thomas, S.B.; Rose, F.A.
The intracellular distribution of arylsulphatase C and oestrogen sulphatase activities in rat kidney and spleen
Biochem. J.
158
631-633
1976
Rattus norvegicus
Nelson, K.; Keinanen, B.M.; Daniel, W.L.
Murine arylsulfatase C: evidence for two isozymes
Experientia
39
740-742
1983
Mus musculus
Burns, G.R.J.
Purification and partial characterization of arylsulphatase C from human placental microsomes
Biochim. Biophys. Acta
759
199-204
1983
Homo sapiens
Noel, H.; Plante, L.; Bleau, G.; Chapdelaine, A.; Roberts, K.D.
Human placental steroid sulfatase: purification and properties
J. Steroid Biochem.
19
1591-1598
1983
Homo sapiens
Simard, J.P.S.; Ameen, M.; Chang, P.L.
Biochemical characterization of arylsulfatase-C isozymes in human fibroblasts
Biochem. Biophys. Res. Commun.
128
1388-1394
1985
Homo sapiens
Conary, J.; Nauerth, A.; Burns, G.; Hasilik, A.; von Figura, K.
Steroid sulfatase. Biosynthesis and processing in normal and mutant fibroblasts
Eur. J. Biochem.
158
71-76
1986
Homo sapiens
Dibbelt, L.; Kuss, E.
Human placental steryl-sulfatase. Enzyme purification, production of antisera, and immunoblotting reactions with normal and sulfatase-deficient placentas
Biol. Chem. Hoppe-Seyler
367
1223-1229
1986
Homo sapiens
Dibbelt, L.; Kuss, E.
Human placental steroid-sulfatase. Kinetics of the in-vitro hydrolysis of dehydroepiandrosterone 3-sulfate and of 16 alpha-hydroxydehydroepiandrosterone 3-sulfate
Hoppe-Seyler's Z. Physiol. Chem.
364
187-191
1983
Homo sapiens
Vaccaro, A.M.; Salvioli, R.; Muscillo, M.; Renola, L.
Purification and properties of arylsulfatase C from human placenta
Enzyme
37
115-126
1987
Homo sapiens
Yen, P.H.; Allen, E.; Marsh, B.; Mohandas, T.; Wang, N.; Taggart, R.T.; Shapiro, L.J.
Cloning and expression of steroid sulfatase cDNA and the frequent occurrence of deletions in STS deficiency: implications for X-Y interchange
Cell
49
443-454
1987
Homo sapiens
Bonifas, J.M.; Morley, B.J.; Oakey, R.E.; Kan, Y.W.Epstein E.H.
Cloning of a cDNA for steroid sulfatase: frequent occurrence of gene deletions in patients with recessive X chromosome-linked ichthyosis
Proc. Natl. Acad. Sci. USA
84
9248-9251
1987
Homo sapiens
Moriyasu, M.; Ito, A.; Omura, T.
Purification and properties of arylsulfatase C from rat liver microsomes
J. Biochem.
92
1189-1195
1982
Rattus norvegicus
Roy, A.B.
The steroid sulphatase of Patella vulgata
Biochim. Biophys. Acta
15
300-301
1954
Patella vulgata
Van Eldere, J.R.; De Pauw, G.; Eyssen, H.J.
Steroid sulfatase activity in a Peptococcus niger strain from the human intestinal microflora
Appl. Environ. Microbiol.
53
1655-1660
1987
Peptococcus niger
Dibbelt, L.; Kuss, E.
Human placental steroid-sulfatase solubilized with a cholic-acid derivative: molecular mass, kinetic properties and susceptibility to glycosidases [retracted by Dibbelt L, Kuss E. In: Biol Chem Hoppe Seyler 1991 Mar;372(3):186]
Hoppe-Seyler's Z. Physiol. Chem.
365
1145-1153
1984
Homo sapiens
Tseng, L.; Mazella, J.; Lee, L.Y.; Stone, M.L.
Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma
J. Steroid Biochem.
19
1413-1417
1983
Homo sapiens
Iwamori, M.; Moser, H.W.; Kishimoto, Y.
Solubilization and partial purification of steroid sulfatase from rat liver: characterization of estrone sulfatase
Arch. Biochem. Biophys.
174
199-208
1976
Rattus norvegicus
Payne, A.H.
Gonadal steroid sulfates and sulfatase. V. Human testicular steroid sulfatase: partial characterization and possible regulation by free steroids
Biochim. Biophys. Acta
258
473-483
1972
Homo sapiens
Shankaran, R.; Ameen, M.; Daniel, W.L.; Davidson, R.G.; Chang, P.L.
Characterization of arylsulfatase C isozymes from human liver and placenta
Biochim. Biophys. Acta
1078
251-257
1991
Homo sapiens
Suzuki, T.; Hirato, K.; Yanaihara, T.; Kadofuku, T.; Sato, T.; Hoshino, M.; Yanaihara, N.
Purification and properties of steroid sulfatase from human placenta
Endocrinol. Jpn.
39
93-101
1992
Homo sapiens
Haning, R.V., Jr.; Hackett, R.J.; Canick, J.A.
Steroid sulfatase in the human ovary and placenta: enzyme kinetics and phosphate inhibition
J. Steroid Biochem. Mol. Biol.
41
161-165
1992
Homo sapiens
Mortaud, S.; Donsez-Darcel, E.; Roubertoux, P.L.; Degrelle, H.
Murine steroid sulfatase (mSTS): purification, characterization and measurement by ELISA
J. Steroid Biochem. Mol. Biol.
52
91-96
1995
Mus musculus
Purohit, A.; Reed, M.J.; Morris, N.C.; Williams, G.J.; Potter, B.V.
Regulation and inhibition of steroid sulfatase activity in breast cancer
Ann. N. Y. Acad. Sci.
784
40-49
1996
Homo sapiens
Wong, C.K.; Keung, W.M.
Daidzein sulfoconjugates are potent inhibitors of sterol sulfatase (EC 3.1.6.2)
Biochem. Biophys. Res. Commun.
233
579-583
1997
Mesocricetus auratus
Park, I.H.; Han, B.K.; Jo, D.H.
Distribution and characterization of neurosteroid sulfatase from the bovine brain
J. Steroid Biochem. Mol. Biol.
62
315-320
1997
Bos taurus
Alperin, E.S.; Shapiro, L.J.
Characterization of point mutations in patients with X-linked ichthyosis. Effects on the structure and function of the steroid sulfatase protein
J. Biol. Chem.
272
20756-20763
1997
Homo sapiens
Rhodes, M.E.; Li, P.K.; Burke, A.M.; Johnson, D.A.
Enhanced plasma DHEAS, brain acetylcholine and memory mediated by steroid sulfatase inhibition
Brain Res.
773
28-32
1997
Rattus norvegicus
Purohit, A.; Potter, B.V.; Parker, M.G.; Reed, M.J.
Steroid sulphatase: expression, isolation and inhibition for active-site identification studies
Chem. Biol. Interact.
109
183-193
1998
Helix pomatia, Homo sapiens
Woo, L.W.; Howarth, N.M.; Purohit, A.; Hejaz, H.A.; Reed, M.J.; Potter, B.V.
Steroidal and nonsteroidal sulfamates as potent inhibitors of steroid sulfatase
J. Med. Chem.
41
1068-1083
1998
Homo sapiens
Slavakis, A.P.; Oakey, R.E.
Aromatase activity of steroid sulphatase-deficient placentae
J. Steroid Biochem.
19
1599-1603
1983
Homo sapiens
Nagamine, C.M.; Michot, J.L.; Roberts, C.; Guenet, J.L.; Bishop, C.E.
Linkage of the murine steroid sulfatase locus, Sts, to sex reversed, Sxr: a genetic and molecular analysis
Nucleic Acids Res.
15
9227-9238
1987
Mus musculus
Van der Loos, C.M.; van Breda, A.J.; van den Berg, F.M.; Jobsis, A.C.
The nature of placental steroid sulphatase deficiency in man
J. Steroid Biochem.
19
1743-1746
1983
Homo sapiens
Nakamura, Y.; Miki, Y.; Suzuki, T.; Nakata, T.; Darnel, A.D.; Moriya, T.; Tazawa, C.; Saito, H.; Ishibashi, T.; Takahashi, S.; Yamada, S.; Sasano, H.
Steroid sulfatase and estrogen sulfotransferase in the atherosclerotic human aorta
Am. J. Pathol.
163
1329-1339
2003
Homo sapiens
Miki, Y.; Nakata, T.; Suzuki, T.; Darnel, A.D.; Moriya, T.; Kaneko, C.; Hidaka, K.; Shiotsu, Y.; Kusaka, H.; Sasano, H.
Systemic distribution of steroid sulfatase and estrogen sulfotransferase in human adult and fetal tissues
J. Clin. Endocrinol. Metab.
87
5760-5768
2002
Homo sapiens
Sugawara, T.; Fujimoto, S.
The potential function of steroid sulphatase activity in steroid production and steroidogenic acute regulatory protein expression
Biochem. J.
380
153-160
2004
Homo sapiens
Bonser, J.; Walker, J.; Purohit, A.; Reed, M.J.; Potter, B.V.L.; Willis, D.S.; Franks, S.; Mason, H.D.
Human granulosa cells are a site of sulphatase activity and are able to utilize dehydroepiandrosterone sulphate as a precursor for oestradiol production
J. Endocrinol.
167
465-471
2000
Homo sapiens
Hoffmann, R.; Rot, A.; Niiyama, S.; Billich, A.
Steroid sulfatase in the human hair follicle concentrates in the dermal papilla
J. Invest. Dermatol.
117
1342-1348
2001
Homo sapiens
Steckelbroeck, S.; Nassen, A.; Ugele, B.; Ludwig, M.; Watzka, M.; Reissinger, A.; Clusmann, H.; Ltjohann, D.; Siekmann, L.; Klingmller, D.; Hans, V.H.
Steroid sulfatase (STS) expression in the human temporal lobe: enzyme activity, mRNA expression and immunohistochemistry study
J. Neurochem.
89
403-417
2004
Homo sapiens
Park, I.H.; Han, B.K.; Baek, J.H.; Ryu, Y.W.; Park, Y.H.; Jo, D.H.
Subunits of neurosteroid sulfatase from bovine brain
J. Steroid Biochem. Mol. Biol.
73
135-139
2000
Bos taurus
Clemens, J.W.; Kabler, H.L.; Sarap, J.L.; Beyer, A.R.; Li, P.K.; Selcer, K.W.
Steroid sulfatase activity in the rat ovary, cultured granulosa cells, and a granulosa cell line
J. Steroid Biochem. Mol. Biol.
75
245-252
2000
Rattus norvegicus
Malini, B.; Purohit, A.; Ganeshapillai, D.; Woo, L.W.L.; Potter, B.V.L.; Reed, M.J.
Inhibition of steroid sulphatase activity by tricyclic coumarin sulphamates
J. Steroid Biochem. Mol. Biol.
75
253-258
2000
Rattus norvegicus
Newman, S.P.; Purohit, A.; Ghilchik, M.W.; Potter, B.V.L.; Reed, M.J.
Regulation of steroid sulphatase expression and activity in breast cancer
J. Steroid Biochem. Mol. Biol.
75
259-264
2000
Homo sapiens
Hernandez-Guzman, F.G.; Higashiyama, T.; Osawa, Y.; Ghosh, D.
Purification, characterization and crystallization of human placental estrone/dehydroepiandrosterone sulfatase, a membrane-bound enzyme of the endoplasmic reticulum
J. Steroid Biochem. Mol. Biol.
78
441-450
2001
Homo sapiens
Norkowska, M.; Gniot-Szulzycka, J.
Sterolsulphate sulphohydrolase from human placenta microsomes--30 kDa molecular weight form of cholesterol sulphate sulphohydrolase
J. Steroid Biochem. Mol. Biol.
81
263-271
2002
Homo sapiens
Tobacman, J.K.; Hinkhouse, M.; Khalkhali-Ellis, Z.
Steroid sulfatase activity and expression in mammary myoepithelial cells
J. Steroid Biochem. Mol. Biol.
81
65-68
2002
Homo sapiens
Shields-Botella, J.; Bonnet, P.; Duc, I.; Duranti, E.; Meschi, S.; Cardinali, S.; Prouheze, P.; Chaigneau, A.M.; Duranti, V.; Gribaudo, S.; Riviere, A.; Mengual, L.; Carniato, D.; Cecchet, L.; Lafay, J.; Rondot, B.; Sandri, J.; Pascal, J.C.; Delansorne, R.
In vitro and in vivo models for the evaluation of new inhibitors of human steroid sulfatase, devoid of residual estrogenic activity
J. Steroid Biochem. Mol. Biol.
84
327-335
2003
Homo sapiens, Rattus norvegicus
Fischer, D.S.; Chander, S.K.; Woo, L.W.L.; Fenton, J.C.; Purohit, A.; Reed, M.J.; Potter, B.V.L.
Novel D-ring modified steroid derivatives as potent, non-estrogenic, steroid sulfatase inhibitors with in vivo activity
J. Steroid Biochem. Mol. Biol.
84
343-349
2003
Rattus norvegicus
Nakata, T.; Takashima, S.; Shiotsu, Y.; Murakata, C.; Ishida, H.; Akinaga, S.; Li, P.K.; Sasano, H.; Suzuki, T.; Saeki, T.
Role of steroid sulfatase in local formation of estrogen in post-menopausal breast cancer patients
J. Steroid Biochem. Mol. Biol.
86
455-460
2003
Homo sapiens
Walter, G.; Liebl, R.; von Angerer, E.
2-Phenylindole sulfamates: inhibitors of steroid sulfatase with antiproliferative activity in MCF-7 breast cancer cells
J. Steroid Biochem. Mol. Biol.
88
409-420
2004
Homo sapiens
Yanaihara, A.; Yanaihara, T.; Toma, Y.; Shimizu, Y.; Saito, H.; Okai, T.; Higashiyama, T.; Osawa, Y.
Localization and expression of steroid sulfatase in human fallopian tubes
Steroids
66
87-91
2001
Homo sapiens
Chander, S.K.; Purohit, A.; Woo, L.W.; Potter, B.V.; Reed, M.J.
The role of steroid sulphatase in regulating the oestrogenicity of oestrogen sulphamates
Biochem. Biophys. Res. Commun.
322
217-222
2004
Rattus norvegicus
Utsunomiya, H.; Ito, K.; Suzuki, T.; Kitamura, T.; Kaneko, C.; Nakata, T.; Niikura, H.; Okamura, K.; Yaegashi, N.; Sasano, H.
Steroid sulfatase and estrogen sulfotransferase in human endometrial carcinoma
Clin. Cancer Res.
10
5850-5856
2004
Homo sapiens
Yanaihara, A.; Otsuka, Y.; Iwasaki, S.; Okai, T.; Yanaihara, T.
Strong expression of steroid sulfatase in human cumulus cells in patients with endometriosis
Fertil. Steril.
84
464-467
2005
Homo sapiens
Hughes, P.J.; Steinmeyer, A.; Chandraratna, R.A.; Brown, G.
1alpha,25-dihydroxyvitamin D3 stimulates steroid sulphatase activity in HL60 by and NB4 acute myeloid leukaemia cell lines different receptor-mediated mechanisms
J. Cell. Biochem.
94
1175-1189
2005
Homo sapiens
Sugawara, T.; Nomura, E.; Hoshi, N.
Both N-terminal and C-terminal regions of steroid sulfatase are important for enzyme activity
J. Endocrinol.
188
365-374
2006
Homo sapiens
Horvath, A.; Nussbaumer, P.; Wolff, B.; Billich, A.
2-(1-adamantyl)-4-(thio)chromenone-6-carboxylic acids: potent reversible inhibitors of human steroid sulfatase
J. Med. Chem.
47
4268-4276
2004
Homo sapiens
Kriz, L.; Bicikova, M.; Hill, M.; Hampl, R.
Steroid sulfatase and sulfuryl transferase activity in monkey brain tissue
Steroids
70
960-969
2005
Macaca mulatta
Bhattacharyya, S.; Tobacman, J.K.
Steroid sulfatase, arylsulfatases A and B, galactose-6-sulfatase, and iduronate sulfatase in mammary cells and effects of sulfated and non-sulfated estrogens on sulfatase activity
J. Steroid Biochem. Mol. Biol.
103
20-34
2007
Homo sapiens
Nakamura, Y.; Suzuki, T.; Fukuda, T.; Ito, A.; Endo, M.; Moriya, T.; Arai, Y.; Sasano, H.
Steroid sulfatase and estrogen sulfotransferase in human prostate cancer
Prostate
66
1005-1012
2006
Homo sapiens
Ahmed, V.; Liu, Y.; Silvestro, C.; Taylor, S.D.
Boronic acids as inhibitors of steroid sulfatase
Bioorg. Med. Chem.
14
8564-8573
2006
Homo sapiens
Bochkareva, N.V.; Kondakova, I.V.; Kolomiets, L.A.; Muntyan, A.B.; Shevchenko, V.P.; Nagaev, I.Y.; Shevchenko, K.V.; Myasoedov, N.F.; Dorofeeva, N.N.
Synthesis of highly tritium labeled steroids for evaluation of aromatase and steroidsulfatase activities in endometrial tumors
Bull. Exp. Biol. Med.
142
478-480
2006
Homo sapiens
Valle, L.D.; Toffolo, V.; Nardi, A.; Fiore, C.; Bernante, P.; Di Liddo, R.; Parnigotto, P.P.; Colombo, L.
Tissue-specific transcriptional initiation and activity of steroid sulfatase complementing dehydroepiandrosterone sulfate uptake and intracrine steroid activations in human adipose tissue
J. Endocrinol.
190
129-139
2006
Homo sapiens (P08842), Homo sapiens
Woo, L.W.; Bubert, C.; Sutcliffe, O.B.; Smith, A.; Chander, S.K.; Mahon, M.F.; Purohit, A.; Reed, M.J.; Potter, B.V.
Dual aromatase-steroid sulfatase inhibitors
J. Med. Chem.
50
3540-3560
2007
Homo sapiens, Rattus norvegicus
Selcer, K.W.; Difrancesca, H.M.; Chandra, A.B.; Li, P.K.
Immunohistochemical analysis of steroid sulfatase in human tissues
J. Steroid Biochem. Mol. Biol.
105
115-123
2007
Homo sapiens (P08842), Homo sapiens
Zaichuk, T.; Ivancic, D.; Scholtens, D.; Schiller, C.; Khan, S.A.
Tissue-specific transcripts of human steroid sulfatase are under control of estrogen signaling pathways in breast carcinoma
J. Steroid Biochem. Mol. Biol.
105
76-84
2007
Homo sapiens
Falany, J.L.; Falany, C.N.
Interactions of the human cytosolic sulfotransferases and steroid sulfatase in the metabolism of tibolone and raloxifene
J. Steroid Biochem. Mol. Biol.
107
202-210
2007
Homo sapiens
Dalla Valle, L.; Toffolo, V.; Nardi, A.; Fiore, C.; Armanini, D.; Belvedere, P.; Colombo, L.
The expression of the human steroid sulfatase-encoding gene is driven by alternative first exons
J. Steroid Biochem. Mol. Biol.
107
22-29
2007
Homo sapiens (P08842), Homo sapiens
Ishida, H.; Sato, N.; Hosogi, J.; Tanaka, H.; Kuwabara, T.
Inactivation of recombinant human steroid sulfatase by KW-2581
J. Steroid Biochem. Mol. Biol.
108
17-22
2008
Homo sapiens
Kriz L.; Bicikova, M.; Mohapl, M.; Hill, M.; Cerny, I.; Hampl, R.
Steroid sulfatase and sulfuryl transferase activities in human brain tumors
J. Steroid Biochem. Mol. Biol.
109
31-39
2007
Homo sapiens
Niewiadomska, I.; Gniot-Szulzycka, J.
Dehydroepiandrosterone sulphate sulphohydrolase from human placenta microsomes - properties of the purified enzyme
J. Steroid Biochem. Mol. Biol.
99
67-75
2006
Homo sapiens
Stanway, S.J.; Delavault, P.; Purohit, A.; Woo, L.W.; Thurieau, C.; Potter, B.V.; Reed, M.J.
Steroid sulfatase: a new target for the endocrine therapy of breast cancer
Oncologist
12
370-374
2007
Homo sapiens
Day, J.M.; Purohit, A.; Tutill, H.J.; Foster, P.A.; Woo, L.W.; Potter, B.V.; Reed, M.J.
The development of steroid sulfatase inhibitors for hormone-dependent cancer therapy
Ann. N. Y. Acad. Sci.
1155
80-87
2009
Homo sapiens
Purohit, A.; Chander, S.K.; Woo, L.W.; Parsons, M.F.; Jhalli, R.; Potter, B.V.; Reed, M.J.
Inhibition of steroid sulphatase activity via the percutaneous route: a new option for breast cancer therapy
Anticancer Res.
28
1517-1523
2008
Mus musculus
Bojarova, P.; Williams, S.J.
Aryl sulfamates are broad spectrum inactivators of sulfatases: effects on sulfatases from various sources
Bioorg. Med. Chem. Lett.
19
477-480
2009
Haliotis sp., Helix pomatia, Patella vulgata
Fournier, D.; Poirier, D.
Estradiol dimers as a new class of steroid sulfatase reversible inhibitors
Bioorg. Med. Chem. Lett.
19
693-696
2009
Homo sapiens
Sato, R.; Suzuki, T.; Katayose, Y.; Miura, K.; Shiiba, K.; Tateno, H.; Miki, Y.; Akahira, J.; Kamogawa, Y.; Nagasaki, S.; Yamamoto, K.; Ii, T.; Egawa, S.; Evans, D.B.; Unno, M.; Sasano, H.
Steroid sulfatase and estrogen sulfotransferase in colon carcinoma: regulators of intratumoral estrogen concentrations and potent prognostic factors
Cancer Res.
69
914-922
2009
Homo sapiens
Bubert, C.; Woo, L.W.; Sutcliffe, O.B.; Mahon, M.F.; Chander, S.K.; Purohit, A.; Reed, M.J.; Potter, B.V.
Synthesis of aromatase inhibitors and dual aromatase steroid sulfatase inhibitors by linking an arylsulfamate motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile: SAR, crystal structures, in vitro and in vivo activities
ChemMedChem
3
1708-1730
2008
Homo sapiens, Rattus norvegicus
Foster, P.A.; Woo, L.W.; Potter, B.V.; Reed, M.J.; Purohit, A.
The use of steroid sulfatase inhibitors as a novel therapeutic strategy against hormone-dependent endometrial cancer
Endocrinology
149
4035-4042
2008
Homo sapiens, Mus musculus
Wood, P.M.; Woo, L.W.; Labrosse, J.R.; Trusselle, M.N.; Abbate, S.; Longhi, G.; Castiglioni, E.; Lebon, F.; Purohit, A.; Reed, M.J.; Potter, B.V.
Chiral aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole template: synthesis, absolute configuration, and in vitro activity
J. Med. Chem.
51
4226-4238
2008
Homo sapiens (P08842)
Woo, L.W.; Fischer, D.S.; Sharland, C.M.; Trusselle, M.; Foster, P.A.; Chander, S.K.; Di Fiore, A.; Supuran, C.T.; De Simone, G.; Purohit, A.; Reed, M.J.; Potter, B.V.
Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography
Mol. Cancer Ther.
7
2435-2444
2008
Rattus norvegicus, Homo sapiens (P08842), Homo sapiens
Stengel, C.; Newman, S.P.; Day, J.M.; Tutill, H.J.; Reed, M.J.; Purohit, A.
Effects of mutations and glycosylations on STS activity: a site-directed mutagenesis study
Mol. Cell. Endocrinol.
283
76-82
2008
Homo sapiens (P08842), Homo sapiens
Mutembei, H.M.; Kowalewski, M.P.; Ugele, B.; Schuler, G.; Hoffmann, B.
Expression and activity of steroid sulphatase in the boar testis
Reprod. Domest. Anim.
44
17-23
2009
Sus scrofa (Q45FD5)
Mortaud, S.; Nicolas, L.; Pinoteau, W.; Tordjman, S.; Carlier, M.; Roubertoux, P.L.
Brain pathways mediating the pro-aggressive effect of the steroid sulfatase (Sts) gene
Behav. Genet.
40
211-219
2010
Mus musculus
Fu, J.; Weise, A.M.; Falany, J.L.; Falany, C.N.; Thibodeau, B.J.; Miller, F.R.; Kocarek, T.A.; Runge-Morris, M.
Expression of estrogenicity genes in a lineage cell culture model of human breast cancer progression
Breast Cancer Res. Treat.
120
35-45
2010
Homo sapiens
Zhang, Y.; Qian, R.Q.; Li, P.P.
Shikonin, an ingredient of Lithospermum erythrorhizon, down-regulates the expression of steroid sulfatase genes in breast cancer cells
Cancer Lett.
284
47-54
2009
Homo sapiens
Ahmed, V.; Liu, Y.; Taylor, S.
Multiple pathways for the irreversible inhibition of steroid sulfatase with quinone methide-generating suicide inhibitors
ChemBioChem
10
1457-1461
2009
Homo sapiens
Gonzalez-Huerta, L.; Mendiola-Jimenez, J.; Del Moral-Stevenel, M.; Rivera-Vega, M.; Cuevas-Covarrubias, S.
Atypical X-linked ichthyosis in a patient with a large deletion involving the steroid sulfatase (STS) gene
Int. J. Dermatol.
48
142-144
2009
Homo sapiens
Zhang, Y.; Li, P.P.
Shu-Gan-Liang-Xue Decoction, a Chinese herbal formula, down-regulates the expression of steroid sulfatase genes in human breast carcinoma MCF-7 cells
J. Ethnopharmacol.
127
620-624
2010
Homo sapiens
Woo, L.W.; Jackson, T.; Putey, A.; Cozier, G.; Leonard, P.; Acharya, K.R.; Chander, S.K.; Purohit, A.; Reed, M.J.; Potter, B.V.
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template
J. Med. Chem.
53
2155-2170
2010
Homo sapiens
Nardi, A.; Pomari, E.; Zambon, D.; Belvedere, P.; Colombo, L.; Dalla Valle, L.
Transcriptional control of human steroid sulfatase
J. Steroid Biochem. Mol. Biol.
115
68-74
2009
Homo sapiens (P08842), Homo sapiens
Fournier, M.A.; Poirier, D.
Estrogen formation in endometrial and cervix cancer cell lines: involvement of aromatase, steroid sulfatase and 17beta-hydroxysteroid dehydrogenases (types 1, 5, 7 and 12)
Mol. Cell. Endocrinol.
301
142-145
2009
Homo sapiens
Marcos, J.; Craig, W.Y.; Palomaki, G.E.; Kloza, E.M.; Haddow, J.E.; Roberson, M.; Bradley, L.A.; Shackleton, C.H.
Maternal urine and serum steroid measurements to identify steroid sulfatase deficiency (STSD) in second trimester pregnancies
Prenat. Diagn.
29
771-780
2009
Homo sapiens
Langlois, S.; Armstrong, L.; Gall, K.; Hulait, G.; Livingston, J.; Nelson, T.; Power, P.; Pugash, D.; Siciliano, D.; Steinraths, M.; Mattman, A.
Steroid sulfatase deficiency and contiguous gene deletion syndrome amongst pregnant patients with low serum unconjugated estriols
Prenat. Diagn.
29
966-974
2009
Homo sapiens
Wang, M.; Mickens, J.; Gao, M.; Miller, K.D.; Sledge, G.W.; Hutchins, G.D.; Zheng, Q.H.
Design and synthesis of carbon-11-labeled dual aromatase-steroid sulfatase inhibitors as new potential PET agents for imaging of aromatase and steroid sulfatase expression in breast cancer
Steroids
74
896-905
2009
Homo sapiens
Woo, L.W.; Ganeshapillai, D.; Thomas, M.P.; Sutcliffe, O.B.; Malini, B.; Mahon, M.F.; Purohit, A.; Potter, B.V.
Structure-activity relationship for the first-in-class clinical steroid sulfatase inhibitor irosustat (STX64, BN83495)
ChemMedChem
6
2019-2034
2011
Homo sapiens
Shah, K.; Cartledge, T.; Ahmed, S.
Estrone sulfatase, a target enzyme in the treatment of hormone-dependent breast cancer
Drugs Future
35
729-745
2010
Homo sapiens
-
Fournier, D.; Poirier, D.
Chemical synthesis and evaluation of 17alpha-alkylated derivatives of estradiol as inhibitors of steroid sulfatase
Eur. J. Med. Chem.
46
4227-4237
2011
Homo sapiens
Suzuki, T.; Miki, Y.; Nakamura, Y.; Ito, K.; Sasano, H.
Steroid sulfatase and estrogen sulfotransferase in human carcinomas
Mol. Cell. Endocrinol.
340
148-153
2011
Homo sapiens
Purohit, A.; Woo, L.W.; Potter, B.V.
Steroid sulfatase: a pivotal player in estrogen synthesis and metabolism
Mol. Cell. Endocrinol.
340
154-160
2011
Homo sapiens
Phan, C.M.; Liu, Y.; Kim, B.M.; Mostafa, Y.; Taylor, S.D.
Inhibition of steroid sulfatase with 4-substituted estrone and estradiol derivatives
Bioorg. Med. Chem.
19
5999-6005
2011
Homo sapiens
Uduwela, D.; Pabis, A.; Stevenson, B.; Kamerlin, S.; McLeod, M.
Enhancing the steroid sulfatase activity of the arylsulfatase from Pseudomonas aeruginosa
ACS Catal.
8
8902-8914
2018
Pseudomonas aeruginosa (P51691), Pseudomonas aeruginosa DSM 22644 (P51691)
-
Ganeshapillai, D.; Woo, L.W.L.; Thomas, M.P.; Purohit, A.; Potter, B.V.L.
C-3- and C-4-substituted bicyclic coumarin sulfamates as potent steroid sulfatase inhibitors
ACS omega
3
10748-10772
2018
Homo sapiens
Mostafa, Y.A.; Kralt, B.; Rao, P.P.; Taylor, S.D.
A-ring substituted 17beta-arylsulfonamides of 17beta-aminoestra-1,3,5(10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfatase
Bioorg. Med. Chem.
23
5681-5692
2015
Homo sapiens (P08842)
El-Gamal, M.I.; Semreen, M.H.; Foster, P.A.; Potter, B.V.
Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors
Bioorg. Med. Chem.
24
2762-2767
2016
Homo sapiens (P08842)
Stevenson, B.J.; Waller, C.C.; Ma, P.; Li, K.; Cawley, A.T.; Ollis, D.L.; McLeod, M.D.
Pseudomonas aeruginosa arylsulfatase a purified enzyme for the mild hydrolysis of steroid sulfates
Drug Test. Anal.
7
903-911
2015
Pseudomonas aeruginosa (P51691), Pseudomonas aeruginosa DSM 22644 (P51691)
Dasko, M.; Przybylowska, M.; Rachon, J.; Maslyk, M.; Kubinski, K.; Misiak, M.; Skladanowski, A.; Demkowicz, S.
Synthesis and biological evaluation of fluorinated N-benzoyl and N-phenylacetoyl derivatives of 3-(4-aminophenyl)-coumarin-7-O-sulfamate as steroid sulfatase inhibitors
Eur. J. Med. Chem.
128
79-87
2017
Homo sapiens (P08842), Homo sapiens
Paitz, R.T.; Duffield, K.R.; Bowden, R.M.
Characterizing the distribution of steroid sulfatase during embryonic development when and where might metabolites of maternal steroids be reactivated?
J. Exp. Biol.
220
4567-4570
2017
Trachemys scripta
Salah, M.; Abdelsamie, A.S.; Frotscher, M.
First dual inhibitors of steroid sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) designed multiple ligands as novel potential therapeutics for estrogen-dependent diseases
J. Med. Chem.
60
4086-4092
2017
Homo sapiens (P08842)
Gibson, D.A.; Foster, P.A.; Simitsidellis, I.; Critchley, H.O.D.; Kelepouri, O.; Collins, F.; Saunders, P.T.K.
Sulfation pathways A role for steroid sulphatase in intracrine regulation of endometrial decidualisation
J. Mol. Endocrinol.
61
M57-M65
2018
Homo sapiens (P08842), Homo sapiens
Blaschka, C.; Schuler, G.; Sanchez-Guijo, A.; Zimmer, B.; Feller, S.; Kotarski, F.; Wudy, S.A.; Wrenzycki, C.
Occurrence of sulfonated steroids and ovarian expression of steroid sulfatase and SULT1E1 in cyclic cows
J. Steroid Biochem. Mol. Biol.
179
79-87
2018
Bos taurus (A6P7M0), Bos taurus
Kurogi, K.; Yoshihama, M.; Williams, F.E.; Kenmochi, N.; Sakakibara, Y.; Suiko, M.; Liu, M.C.
Identification of zebrafish steroid sulfatase and comparative analysis of the enzymatic properties with human steroid sulfatase
J. Steroid Biochem. Mol. Biol.
185
110-117
2019
Danio rerio (F1QB82), Danio rerio, Homo sapiens (P08842), Homo sapiens
html completed
