3.1.6.2: steryl-sulfatase

This is an abbreviated version!
For detailed information about steryl-sulfatase, go to the full flat file.

Word Map on EC 3.1.6.2

3.1.6.2

women

testosterone

androgen

adrenal

cortisol

estradiol

estrogen

androstenedione

sulphate

globulin

polycystic

ovary

fsh

x-linked

ovarian

postmenopausal

ichthyosis

progesterone

acth

aromatase

hyperandrogenism

neurosteroids

hirsutism

menstrual

hormone-binding

prolactin

luteinizing

17-hydroxyprogesterone

premenopausal

adrenarche

sulfotransferase

hormone-dependent

sulfamate

endocrinology

hyperandrogenemia

17beta-hydroxysteroid

hypothalamic-pituitary-adrenal

pubertal

pharmacology

21-hydroxylase

alpha-hydroxyprogesterone

17beta-hsds

dhea-s

virilization

tanner

11-deoxycortisol

allopregnanolone

sulfatases

kallmann

medicine

analysis

pregs

incidentalomas

Reaction

3beta-hydroxyandrost-5-en-17-one 3-sulfate

Synonyms

3-beta-hydroxysteroid sulfate sulfatase, arylsufatase, arylsulfatase C, ASC, AtsA, cholesterol sulfate sulfohydrolase, CHS-ase, dehydroepiandrosterone sulfatase, dehydroepiandrosterone sulfate sulfatase, DHEAS, E1-STS, ES, estrone sulfatase, More, neurosteroid sulfatase, NSS, oestrone sulfatase, phenolic steroid sulfatase, pregnenolone sulfatase, steroid 3-sulfatase, steroid sulfatase, steroid sulfate sulfohydrolase, steroid sulphatase, sterol sulfatase, sterolsulfate sulfohydrolase, Steryl-sulfate sulfohydrolase, STS, sulfatase, sterol

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.6 Sulfuric-ester hydrolases

3.1.6.2 steryl-sulfatase

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Results	in table
21	Activating Compound
41	AA Sequence
39	Application
1	CAS Registry Number
15	Cloned(Commentary)
6	Crystallization (Commentary)
4500	Disease/ Diagnostics
6	Expression
10	General Information
1	General Stability
98	IC50 Value
328	Inhibitors
25	Ki Value [mM]
76	KM Value [mM]
57	Localization
6	Metals/Ions
45	Molecular Weight [Da]
90	Natural Substrates/ Products (Substrates)
134	Organism
2	Pathway
1	PDB ID
33	pH Optimum
3	pH Range
2	pI Value
15	Posttranslational Modification
35	Protein Variants
21	Purification (Commentary)
1	Reaction
1	Reaction Type
131	Reference
216	Source Tissue
15	Specific Activity [micromol/min/mg]
4	Storage Stability
251	Substrates and Products (Substrate)
14	Subunits
114	Synonyms
1	Systematic Name
15	Temperature Optimum [°C]
1	Temperature Range [°C]
15	Temperature Stability [°C]
1	Turnover Number [1/s]

pH Optimum

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pH Optimum on EC 3.1.6.2 - steryl-sulfatase

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and pH 7.4, 2 optima

4.5

flat optimum

4.6

assay at

5 - 5.5

6.4

6.5 - 8.7

6.6

dehydroepiandrosterone 3-sulfate

6.8

6.9

f-form

7 - 7.2

7 - 7.5

STS from temporal lobe

656590

7.3

Homo sapiens

p-nitrophenyl sulfate

7.3 - 7.5

7.4

7.5

assay at

7.5 - 8

placenta

7.7

fast form

8.4

Pseudomonas aeruginosa

135595

9 - 9.8

Chlamydomonas reinhardtii

135595