1.1.1.B4: (R)-specific secondary alcohol dehydrogenase (NADH)

This is an abbreviated version, for detailed information about (R)-specific secondary alcohol dehydrogenase (NADH), go to the full flat file.

Reaction

(R)-R-CHOH-R'
+
NAD+
=
R-CO-R'
+
NADH
+
H+

Synonyms

ADH, ADH1, ADH2, ADHTt, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CHY1186, CpCR, More, SDR, short-chain NAD(H)-dependent alcohol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B4 (R)-specific secondary alcohol dehydrogenase (NADH)

Metals Ions

Metals Ions on EC 1.1.1.B4 - (R)-specific secondary alcohol dehydrogenase (NADH)

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Ca2+
-
5 mM, 156% of initial activity
EDTA
-
activates to 127% activity compared to the control activity at 1 mM and to 163% at 10 mM
K+
-
activates to 167% activity compared to the control activity at 1 mM and to 193% at 100 mM
Li+
-
activates to 127% activity compared to the control activity at 1 mM and to 178% at 100 mM
Mg2+
-
5 mM, 109% of initial activity
Na+
-
activates to 179 at 100 mM
NH4+
-
5 mM, 124% of initial activity
Zn2+
-
activates to 114% activity compared to the control activity at 1 mM
ZnSO4
-
1mM, 135% of initial activity