1.1.1.B4: (R)-specific secondary alcohol dehydrogenase (NADH)

This is an abbreviated version, for detailed information about (R)-specific secondary alcohol dehydrogenase (NADH), go to the full flat file.

Reaction

(R)-R-CHOH-R'
+
NAD+
=
R-CO-R'
+
NADH
+
H+

Synonyms

ADH, ADH1, ADH2, ADHTt, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CHY1186, CpCR, More, SDR, short-chain NAD(H)-dependent alcohol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B4 (R)-specific secondary alcohol dehydrogenase (NADH)

KCat KM Value

KCat KM Value on EC 1.1.1.B4 - (R)-specific secondary alcohol dehydrogenase (NADH)

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
50.1
2,3-Butanedione
-
pH 7.4, 30°C
36.8 - 463
3,5-bis(trifluoromethyl)acetophenone
-
4.1
ethyl 4-chloro-3-oxobutanoate
-
pH 7.4, 30°C
75 - 4207
NADH
5100 - 9300
NADPH