1.1.1.B4: (R)-specific secondary alcohol dehydrogenase

This is an abbreviated version, for detailed information about (R)-specific secondary alcohol dehydrogenase, go to the full flat file.

Reaction

(R)-R-CHOH-R'
+
NAD+
=
R-CO-R'
+
NADH
+
H+

Synonyms

ADH, ADH1, ADH2, ADHTt, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CHY1186, More, SDR, short-chain NAD(H)-dependent alcohol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B4 (R)-specific secondary alcohol dehydrogenase

Turnover Number

Turnover Number on EC 1.1.1.B4 - (R)-specific secondary alcohol dehydrogenase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1 - 1.7
(R)-2-butanol
1.1 - 1.9
(R)-2-pentanol
25.5
2,2,2-trifluoroacetophenone
Thermus thermophilus
-
pH 6.0, 65C, recombinant enzyme, reduction reaction
3.97
ethyl 2-oxopropanoate
Carboxydothermus hydrogenoformans
Q3ACV3
pH 6.5, 50C
-
50.1
ethylbenzoylformate
Thermus thermophilus
-
pH 6.0, 65C, recombinant enzyme, reduction reaction
0.84
NAD+
Thermus thermophilus
-
pH 6.0, 65C, recombinant enzyme, reduction reaction
52.4
NADH
Thermus thermophilus
-
pH 6.0, 65C, recombinant enzyme, reduction reaction