1.1.1.B4: (R)-specific secondary alcohol dehydrogenase

This is an abbreviated version, for detailed information about (R)-specific secondary alcohol dehydrogenase, go to the full flat file.

Reaction

(R)-R-CHOH-R'
+
NAD+
=
R-CO-R'
+
NADH
+
H+

Synonyms

ADH, ADH1, ADH2, ADHTt, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CHY1186, More, SDR, short-chain NAD(H)-dependent alcohol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B4 (R)-specific secondary alcohol dehydrogenase

Temperature Stability

Temperature Stability on EC 1.1.1.B4 - (R)-specific secondary alcohol dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
-
wild-type, half-life 160 h, mutant R38P, half-life 220 h
42
-
wild-type, half-life 1.25 h, mutant R38P, half-life 3 h
50
-
24 h, purified recombinant enzyme, 142% inactivation
60
-
24 h, purified recombinant enzyme, 134% inactivation
90
-
30 min, purified recombinant enzyme, 50% inactivation