1.1.1.B4: (R)-specific secondary alcohol dehydrogenase

This is an abbreviated version, for detailed information about (R)-specific secondary alcohol dehydrogenase, go to the full flat file.

Reaction

(R)-R-CHOH-R'
+
NAD+
=
R-CO-R'
+
NADH
+
H+

Synonyms

ADH, ADH1, ADH2, ADHTt, carbonyl reductase (NADH, specific for (S)-configuration of alcohol), CHY1186, More, SDR, short-chain NAD(H)-dependent alcohol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B4 (R)-specific secondary alcohol dehydrogenase

Molecular Weight

Molecular Weight on EC 1.1.1.B4 - (R)-specific secondary alcohol dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
26000
-
4 * 26961, recombinant enzyme, mass spectrometry, 4 * 26000, recombinant enzyme, SDS-PAGE
26961
-
4 * 26961, recombinant enzyme, mass spectrometry, 4 * 26000, recombinant enzyme, SDS-PAGE
30000
x * 30000, SDS-PAGE and calculated
35000
-
gel filtration
37000
-
4 * 37000, SDS-PAGE
37500
-
x * 37500, SDS-PAGE
37590
4 * 37590, sequence calculation, a tetramer formed by a dimer of dimers
71000
-
about, recombinant enzyme, gel filtration in absence of NaCl
105000
-
about, recombinant enzyme, gel filtration in presence of 0.15 M NaCl
150000
-
gel filtration