1.1.1.209: 3(or 17)alpha-hydroxysteroid dehydrogenase

This is an abbreviated version, for detailed information about 3(or 17)alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

androsterone
+
NAD(P)+
=
5alpha-androstane-3,17-dione
+
NAD(P)H
+
H+

Synonyms

3(17)alpha-hydroxysteroid dehydrogenase, AKR1C21, dehydrogenase, 3(17)alpha-hydroxy steroid, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase

Specific Activity

Specific Activity on EC 1.1.1.209 - 3(or 17)alpha-hydroxysteroid dehydrogenase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0035
-
reduction of 5alpha-dihydrotestosteerone, cofactor NADPH, pH 6.0
0.0063
-
oxidation of 3alpha-androstanediol, cofactor NADP+, pH 9.0
0.0253
-
reduction of 5alpha-androstanedione, cofactor NADPH, pH 6.0
0.27
-
-