1.1.1.209: 3(or 17)alpha-hydroxysteroid dehydrogenase

This is an abbreviated version, for detailed information about 3(or 17)alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

androsterone
+
NAD(P)+
=
5alpha-androstane-3,17-dione
+
NAD(P)H
+
H+

Synonyms

3(17)alpha-hydroxysteroid dehydrogenase, AKR1C21, dehydrogenase, 3(17)alpha-hydroxy steroid, More

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase

Turnover Number

Turnover Number on EC 1.1.1.209 - 3(or 17)alpha-hydroxysteroid dehydrogenase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00617
(2Z)-2-(5-hydroxy-4,6-dimethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-N,N-di(prop-2-en-1-yl)hydrazinecarbothioamide
Homo sapiens
-
-
0.0217 - 0.617
4-androstene-3,17-dione
0.145 - 0.867
5alpha-Androstan-17alpha-ol-3-one
0.0025 - 0.383
5alpha-androstan-17beta-ol-3-one
0.0217 - 0.233
5alpha-Androstan-3alpha-ol-17-one
0.00167 - 0.167
5alpha-androstan-3beta,17beta-diol
0.003
5alpha-dihydrotestosterone
Homo sapiens
-
-
0.105 - 0.15
5alpha-pregnane-3alpha,20alpha-diol
0.055 - 0.14
5beta-androstan-17alpha-ol-3-one
0.383 - 4.83
5beta-pregnane-20alpha-ol-3-one
0.35 - 4.83
5beta-pregnane-3,20-dione
0.00367 - 0.4
5beta-pregnane-3alpha,20alpha-diol
0.000367
androsterone
Homo sapiens
-
-
0.23 - 0.57
Epitestosterone
0.0073 - 0.105
lithocholic acid
0.0009 - 0.04
testosterone